應(yīng)用磁共振組織追蹤技術(shù)評(píng)價(jià)左室心肌力學(xué)參數(shù)的研究
發(fā)布時(shí)間:2018-10-21 15:21
【摘要】:目的:采用心臟磁共振組織追蹤技術(shù)(CMR-TT)測(cè)量健康成年人左室整體和局部心肌力學(xué)參數(shù),并探討其性別和年齡差異。方法:連續(xù)選取2015年10月至2016年8月于烏爾姆大學(xué)醫(yī)院(德國(guó))進(jìn)行1.5T CMR檢查的健康成年人共100名,其中男、女性分別為50名,各性別組分別納入≤50歲和50歲者25名。同時(shí),將100名健康成年人分為低年齡組(≤50歲)和高年齡組(50歲)。進(jìn)行穩(wěn)態(tài)自由進(jìn)動(dòng)序列(SSFP)成像并半自動(dòng)地勾畫左室心內(nèi)、外膜位置后,使用CVI42軟件提供的CMR-TT技術(shù)測(cè)量左室整體和基底段、中間段和心尖段心肌的徑向、周向和縱向應(yīng)變、應(yīng)變率、位移、位移速度、(標(biāo)準(zhǔn)化的)扭轉(zhuǎn)和扭轉(zhuǎn)率峰值,采用t檢驗(yàn)或非參數(shù)檢驗(yàn)比較其性別和年齡差異。結(jié)果:(1)女性整體和局部心肌應(yīng)變、應(yīng)變率大于男性;(2)女性整體和中間段心肌縱向位移速度及中間段心肌縱向位移大于男性;(3)高年齡組整體和局部心肌應(yīng)變大于低年齡組,周向和縱向舒張期應(yīng)變率小于低年齡組;(4)高年齡組整體和局部心肌徑向位移水平大于低年齡組,縱向舒張期位移速度小于低年齡組;(5)扭轉(zhuǎn)、扭轉(zhuǎn)率無(wú)性別和年齡差異。結(jié)論:心臟磁共振組織追蹤技術(shù)可以瞬時(shí)定量檢測(cè)心肌各部分的心肌力學(xué)水平,尤其是在評(píng)估應(yīng)變和應(yīng)變率方面具有優(yōu)勢(shì)性。此外,左室整體和局部的部分力學(xué)參數(shù)存在性別和年齡差異。
[Abstract]:Aim: to measure the global and local myocardial mechanical parameters of left ventricle in healthy adults by cardiac magnetic resonance tissue tracing (CMR-TT), and to explore the gender and age differences. Methods: a total of 100 healthy adults were selected from October 2015 to August 2016 for 1.5T CMR examination at Ulm University Hospital (Germany), including 50 males and 50 females, and 25 healthy adults aged less than 50 years and 50 years old in each sex group, respectively. At the same time, 100 healthy adults were divided into low age group (鈮,
本文編號(hào):2285511
[Abstract]:Aim: to measure the global and local myocardial mechanical parameters of left ventricle in healthy adults by cardiac magnetic resonance tissue tracing (CMR-TT), and to explore the gender and age differences. Methods: a total of 100 healthy adults were selected from October 2015 to August 2016 for 1.5T CMR examination at Ulm University Hospital (Germany), including 50 males and 50 females, and 25 healthy adults aged less than 50 years and 50 years old in each sex group, respectively. At the same time, 100 healthy adults were divided into low age group (鈮,
本文編號(hào):2285511
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