2D-STI與RT-3DE評(píng)估不同支數(shù)冠脈病變的冠心病患者左心室功能
發(fā)布時(shí)間：2018-09-18 15:23
【摘要】：目的： 應(yīng)用二維斑點(diǎn)追蹤（two-dimensional speckle tracking imaging,2D-STI）技術(shù)及實(shí)時(shí)三維超聲心動(dòng)圖（real-time three-dimensional echocardiography,RT-3DE）技術(shù)對(duì)不同支數(shù)冠脈病變的冠心病患者左心室功能及所測(cè)參數(shù)相關(guān)性進(jìn)行研究。 方法： 采用Philips IE33彩色多普勒超聲診斷儀配套QLAB8.0定量分析軟件中的2D-STI技術(shù)及RT-3DE技術(shù)對(duì)冠心病對(duì)照組(0組)27例、單支病變組（1組）34例、雙支病變組（2組）28例、三支病變組（3組）25例、射血分?jǐn)?shù)正常組（N組）48例、射血分?jǐn)?shù)減低組（L組）39例進(jìn)行檢測(cè)分析。 測(cè)量各組RT-3DE參數(shù)：三維超聲舒張末期容積(three dimensional enddiastolic volume,3DEDV)、三維超聲收縮末期容積(three dimensional end systolicvolume,3DESV)、三維超聲射血分?jǐn)?shù)(three dimensional ejection fraction,3DEF)、經(jīng)心率校正的16節(jié)段達(dá)最小收縮容積的時(shí)間標(biāo)準(zhǔn)差[Tmsv16-SD adjusted by theR-R interval, Tmsv16-SD(R-R%)]、經(jīng)心率校正的16節(jié)段達(dá)最小收縮容積的時(shí)間最大差值[Tmsv16-Dif adjusted by the R-R interval, Tmsv16-dif(R-R%)]； 測(cè)量各組2D-STI參數(shù)：左室整體扭轉(zhuǎn)角度峰值(peak twist, Ptw)、心底部旋轉(zhuǎn)角度峰值(rotation on basal plane,PBR)、心尖部旋轉(zhuǎn)角度峰值(rotation on apicalplane, PAR)。 0、1、2、3組之間兩兩比較RT-3DE各參數(shù)、2D-STI各參數(shù)；N組與L組之間比較RT-3DE各參數(shù)、2D-STI各參數(shù)，，并對(duì)各組2D-STI參數(shù)Ptw與RT-3DE參數(shù)3DEF、Tmsv16-SD(R-R%)的相關(guān)性進(jìn)行分析。 結(jié)果： 1、0組、1組、2組、3組兩兩之間RT-3DE收縮功能參數(shù)3DEDV、3DESV、3DEF均有顯著差異(P0.01)； 2、1組、2組、3組RT-3DE同步性參數(shù)Tmsv16-SD(R-R%)、Tmsv16-Dif(R-R%)顯著大于0組(P0.01)；3組RT-3DE同步性參數(shù)Tmsv16-SD(R-R%)、Tmsv16-Dif(R-R%)顯著大于1組(P0.01)；1組、2組之間與2組、3組之間RT-3DE同步性參數(shù)Tmsv16-SD(R-R%)、Tmsv16-Dif(R-R%)差異均無(wú)統(tǒng)計(jì)學(xué)意義（P0.05）； 3、0組、1組、2組、3組之間2D-STI扭轉(zhuǎn)參數(shù)PBR，差異均無(wú)統(tǒng)計(jì)學(xué)意義（P0.05）；2組、3組2D-STI扭轉(zhuǎn)參數(shù)PAR、Ptw均低于0組(P0.05)；0組、1組之間2D-STI扭轉(zhuǎn)參數(shù)PAR、Ptw差異均無(wú)統(tǒng)計(jì)學(xué)意義（P0.05）；1組、2組、3組之間2D-STI扭轉(zhuǎn)參數(shù)PAR、Ptw差異均無(wú)統(tǒng)計(jì)學(xué)意義（P0.05）； 4、L組RT-3DE各參數(shù)3DEDV、3DESV、3DEF、Tmsv16-SD(R-R%)、Tmsv16-Dif(R-R%)及2D-STI參數(shù)PAR、Ptw與N組比較，均有顯著差異(P0.01)；L組2D-STI參數(shù)PBR與N組相比較，差異無(wú)統(tǒng)計(jì)學(xué)意義（P0.05）； 5、0組、1組、2組、3組、N組、L組的2D-STI扭轉(zhuǎn)角度Ptw與相應(yīng)的RT-3DE參數(shù)3DEF、Tmsv16-SD(R-R%)相關(guān)性無(wú)統(tǒng)計(jì)學(xué)意義（P0.05）。 結(jié)論： 1、應(yīng)用RT-3DE技術(shù)及2D-STI技術(shù)可以從射血分?jǐn)?shù)、同步性、扭轉(zhuǎn)角度等方面對(duì)不同支數(shù)冠脈病變的冠心病患者左心室功能進(jìn)行評(píng)估。 2、本課題提示RT-3DE技術(shù)及2D-STI技術(shù)所測(cè)量部分參數(shù)[3DEF與Ptw、Tmsv16-SD(R-R%)與Ptw]之間相關(guān)性不顯著。
[Abstract]:Objective: to study the correlation of left ventricular function and measured parameters in coronary heart disease patients with coronary artery disease by using two-dimensional speckle tracing (two-dimensional speckle tracking imaging,2D-STI) and real-time three-dimensional echocardiography (real-time three-dimensional echocardiography,RT-3DE). Methods: 27 cases of coronary heart disease (CHD) control group (group 0), 34 cases of single vessel disease group (group 1) and 28 cases of double vessel disease group (group 2) were treated by 2D-STI technique and RT-3DE technique in QLAB8.0 quantitative analysis software of Philips IE33 color Doppler ultrasound diagnostic instrument. There were 25 cases in three vessel lesion group (3 groups), 48 cases in normal ejection fraction group (N group) and 39 cases in low ejection fraction group (L group). The RT-3DE parameters of each group were measured as follows: Three-dimensional ultrasound end-diastolic volume (three dimensional enddiastolic volume,3DEDV), three-dimensional ultrasound end-systolic volume (three dimensional end systolicvolume,3DESV), three-dimensional ultrasound ejection fraction (three dimensional ejection fraction,3DEF). [Tmsv16-SD adjusted by theR-R interval, Tmsv16-SD (R-R%)], Tmsv16-Dif adjusted by the R-R interval, Tmsv16-dif (R-R%); 2D-STI parameters of each group were measured: left ventricular global torsion angle peak value (peak twist, Ptw), bottom rotation angle peak (rotation on basal plane,PBR), apex rotation angle peak (rotation on apicalplane, PAR). 01T 2T group compared RT-3DE parameters 2D-STI between two groups. The parameters of RT-3DE 2D-STI were compared between group N and group L, and the correlation between 2D-STI parameter Ptw and RT-3DE parameter 3DEFMS v16-SD (R-R%) was analyzed. Results: 1There were significant differences in the systolic function parameters of RT-3DE between two groups (P0.01), Tmsv16-SD (R-R%) and Tmsv16-Dif (R-R%) were significantly higher than those in 0 group (P0.01). The Tmsv16-SD (R-R%) Tmsv16-Dif (R-R%) of RT-3DE synchronization parameters in the three groups was significantly higher than that in the first group (P0.01) and the RT-3DE synchronization parameters Tmsv16-SD (R-R%) and Tmsv16-Dif (R-R%) were not significantly different between the two groups (P0.05). There was no significant difference in PBR, of 2D-STI torsion parameter between group 1 and group 2 (P0.05). The PAR,Ptw of 2D-STI torsion parameter in group 2 was lower than that in group 0 (P0.05). There was no significant difference in 2D-STI torsion parameter PAR,Ptw between group 1 and group 1 (P0.05). There was no significant difference in 2D-STI torsion parameter PAR,Ptw between group 1 and group 2 (P0.05), and there were significant differences in RT-3DE parameters between group N and group N (P0.01), between group C and group N (P0.01), and there were significant differences between group N and group N in RT-3DE parameters (3DEDVV / 3DESVV16-SD (R-R%), PAR,Ptw (R-R%) and PAR,Ptw in group N (P0.01). There was no significant difference between the 2D-STI torsion angle Ptw and the corresponding RT-3DE parameters (3DEFV / Tmsv16-SD (R-R%) (P0.05), and there was no significant correlation between the 2D-STI torsion angle Ptw and the corresponding RT-3DE parameters (3DEFV / Tmsv16-SD (R-R%). Conclusion: 1. RT-3DE and 2D-STI techniques can be used to measure the ejection fraction and synchronism. The left ventricular function of patients with coronary heart disease with different branches of coronary artery disease was evaluated from the angle of torsion. 2. This study suggests that there is no significant correlation between 3DEF and Ptw,Tmsv16-SD (R-R%) and Ptw in some parameters measured by RT-3DE and 2D-STI techniques.
【學(xué)位授予單位】：南昌大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2014
【分類號(hào)】：R541.4;R540.45
本文編號(hào)：2248324
[Abstract]:Objective: to study the correlation of left ventricular function and measured parameters in coronary heart disease patients with coronary artery disease by using two-dimensional speckle tracing (two-dimensional speckle tracking imaging,2D-STI) and real-time three-dimensional echocardiography (real-time three-dimensional echocardiography,RT-3DE). Methods: 27 cases of coronary heart disease (CHD) control group (group 0), 34 cases of single vessel disease group (group 1) and 28 cases of double vessel disease group (group 2) were treated by 2D-STI technique and RT-3DE technique in QLAB8.0 quantitative analysis software of Philips IE33 color Doppler ultrasound diagnostic instrument. There were 25 cases in three vessel lesion group (3 groups), 48 cases in normal ejection fraction group (N group) and 39 cases in low ejection fraction group (L group). The RT-3DE parameters of each group were measured as follows: Three-dimensional ultrasound end-diastolic volume (three dimensional enddiastolic volume,3DEDV), three-dimensional ultrasound end-systolic volume (three dimensional end systolicvolume,3DESV), three-dimensional ultrasound ejection fraction (three dimensional ejection fraction,3DEF). [Tmsv16-SD adjusted by theR-R interval, Tmsv16-SD (R-R%)], Tmsv16-Dif adjusted by the R-R interval, Tmsv16-dif (R-R%); 2D-STI parameters of each group were measured: left ventricular global torsion angle peak value (peak twist, Ptw), bottom rotation angle peak (rotation on basal plane,PBR), apex rotation angle peak (rotation on apicalplane, PAR). 01T 2T group compared RT-3DE parameters 2D-STI between two groups. The parameters of RT-3DE 2D-STI were compared between group N and group L, and the correlation between 2D-STI parameter Ptw and RT-3DE parameter 3DEFMS v16-SD (R-R%) was analyzed. Results: 1There were significant differences in the systolic function parameters of RT-3DE between two groups (P0.01), Tmsv16-SD (R-R%) and Tmsv16-Dif (R-R%) were significantly higher than those in 0 group (P0.01). The Tmsv16-SD (R-R%) Tmsv16-Dif (R-R%) of RT-3DE synchronization parameters in the three groups was significantly higher than that in the first group (P0.01) and the RT-3DE synchronization parameters Tmsv16-SD (R-R%) and Tmsv16-Dif (R-R%) were not significantly different between the two groups (P0.05). There was no significant difference in PBR, of 2D-STI torsion parameter between group 1 and group 2 (P0.05). The PAR,Ptw of 2D-STI torsion parameter in group 2 was lower than that in group 0 (P0.05). There was no significant difference in 2D-STI torsion parameter PAR,Ptw between group 1 and group 1 (P0.05). There was no significant difference in 2D-STI torsion parameter PAR,Ptw between group 1 and group 2 (P0.05), and there were significant differences in RT-3DE parameters between group N and group N (P0.01), between group C and group N (P0.01), and there were significant differences between group N and group N in RT-3DE parameters (3DEDVV / 3DESVV16-SD (R-R%), PAR,Ptw (R-R%) and PAR,Ptw in group N (P0.01). There was no significant difference between the 2D-STI torsion angle Ptw and the corresponding RT-3DE parameters (3DEFV / Tmsv16-SD (R-R%) (P0.05), and there was no significant correlation between the 2D-STI torsion angle Ptw and the corresponding RT-3DE parameters (3DEFV / Tmsv16-SD (R-R%). Conclusion: 1. RT-3DE and 2D-STI techniques can be used to measure the ejection fraction and synchronism. The left ventricular function of patients with coronary heart disease with different branches of coronary artery disease was evaluated from the angle of torsion. 2. This study suggests that there is no significant correlation between 3DEF and Ptw,Tmsv16-SD (R-R%) and Ptw in some parameters measured by RT-3DE and 2D-STI techniques.
【學(xué)位授予單位】：南昌大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2014
【分類號(hào)】：R541.4;R540.45
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