超聲實時組織彈性成像技術(shù)評估頸動脈斑塊性質(zhì)的應用研究
發(fā)布時間：2018-09-08 14:43
【摘要】：【目的】 本課題是應用實時組織彈性成像（real-time tissue elastography，RTE）技術(shù)獲得頸動脈斑塊動態(tài)彈性圖，利用計算機輔助程序獲得斑塊灰階中位數(shù)（gray-scale median，GSM）。對不同灰階斑塊的超聲彈性圖、彈性評分、彈性參數(shù)（包括彈性硬度指數(shù)和彈性硬度比值）及GSM作一個初步的了解。 【方法】 1、選取2013年1月至2013年12月在我院進行頸部血管檢查患者的85個斑塊,來源于40例患者，，男性21例，女性19例，平均年齡57.3±7.5歲。 2、采用GE LOGIQE9超聲診斷儀，線陣9L探頭，頻率5.0～9.0MHZ。對頸動脈斑塊進行常規(guī)超聲及彈性成像檢查，獲得斑塊的二維灰階圖及彈性動態(tài)圖。 3、根據(jù)斑塊的動態(tài)彈性圖獲得斑塊的彈性評分、彈性參數(shù)。利用計算機輔助程序獲得斑塊的GSM。 4、根據(jù)Gray-weale等[1]提出的分類方案將斑塊分成四組。分析四組斑塊的彈性評分、彈性參數(shù)及GSM的差異。 5、分析斑塊的彈性參數(shù)與斑塊的GSM之間的相關(guān)性。 【結(jié)果】 1、斑塊的RTE圖表現(xiàn)：均質(zhì)低回聲斑塊表現(xiàn)為以均勻的綠色為主；不均質(zhì)低回聲斑塊表現(xiàn)為以不均勻綠色為主或不規(guī)則綠藍相間；不均質(zhì)高回聲斑塊表現(xiàn)為藍色為主或不規(guī)則藍綠相間；均質(zhì)高回聲斑塊表現(xiàn)為藍色為主。 2、斑塊彈性評分、彈性參數(shù)及GSM組間兩兩比較：均質(zhì)低回聲斑塊組與不均質(zhì)高回聲斑塊組及均質(zhì)高回聲斑塊組間有統(tǒng)計學差異（P0.05）；不均質(zhì)低回聲斑塊與不均質(zhì)高回聲斑塊組及均質(zhì)高回聲斑塊組間有統(tǒng)計學差異（P0.05）。 3、斑塊的彈性硬度指數(shù)與斑塊的GSM成線性關(guān)系（r=0.886，P=0.000）；斑塊彈性硬度比值與斑塊的GSM成線性關(guān)系（r=0.810，P=0.000）。 【結(jié)論】 1、不同灰階斑塊具有不同特征的RTE圖。 2、斑塊的彈性評分及彈性參數(shù)能夠反映不同灰階斑塊的軟硬度。 3、斑塊的彈性參數(shù)與斑塊的GSM成線性關(guān)系。
[Abstract]:[objective] in this study, real-time tissue elastography (real-time tissue elastography,RTE) was used to obtain dynamic elastic map of carotid plaques, and the median of plaque gray scale (gray-scale median,GSM) was obtained by computer aided program. The ultrasonic elasticity of plaques with different grayscale was evaluated. Elastic parameters (including elastic hardness index and elastic hardness ratio) and GSM were studied. [methods] 1.Eighty-five plaques were selected from January 2013 to December 2013 in our hospital. There were 40 patients (male 21, female 19, mean age 57.3 鹵7.52). GE LOGIQE9 ultrasound was used with a linear 9L probe with a frequency of 5.0 ~ 9.0MHZ. Carotid plaques were examined by conventional ultrasound and elastic imaging, and two-dimensional gray-scale and elastic dynamic images of plaques were obtained. 3. According to the dynamic elastic maps of plaques, the elastic scores and elastic parameters of plaques were obtained. The patch GSM. 4 was obtained by computer aided program, and the patch was divided into four groups according to the classification scheme proposed by Gray-weale et al. The elastic scores of plaques in four groups were analyzed. The difference between elastic parameters and GSM. 5. The correlation between the elastic parameters of plaque and GSM of plaque was analyzed. [results] 1. The RTE pattern of plaque showed that homogeneous green was dominant in homogeneous hypoechoic plaque; Heterogeneous hypoechoic plaques were characterized by uneven green or irregular greenish-blue phases, and heterogeneous hyperechoic plaques were mainly blue or irregular blue-green patches. Homogeneous hyperechoic plaque showed blue. 2. Plaque elasticity score, elastic parameter and GSM group were compared: there was significant difference between homogeneous hypoechoic plaque group and heterogeneous hyperechoic plaque group and homogeneous hyperechoic plaque group (P0.05). There was significant difference between heterogeneous hypoechoic plaque and heterogeneous hyperechoic plaque group and homogeneous hyperechoic plaque group (P0.05). 3. The elastic hardness index of plaque was linearly correlated with GSM of plaque (r = 0.886P = 0.000). There was a linear relationship between the ratio of elastic hardness of plaque and the GSM of plaque (r = 0.810 / P = 0.000). [conclusion] 1. The RTE diagram with different gray scale plaques has different characteristics. 2. The elastic score and elastic parameters of plaque can reflect. The soft and hard degree of different gray-scale plaques. 3. The elastic parameters of plaques are linearly related to the GSM of plaques.
【學位授予單位】：福建醫(yī)科大學
【學位級別】：碩士
【學位授予年份】：2014
【分類號】：R445.1
本文編號：2230829
[Abstract]:[objective] in this study, real-time tissue elastography (real-time tissue elastography,RTE) was used to obtain dynamic elastic map of carotid plaques, and the median of plaque gray scale (gray-scale median,GSM) was obtained by computer aided program. The ultrasonic elasticity of plaques with different grayscale was evaluated. Elastic parameters (including elastic hardness index and elastic hardness ratio) and GSM were studied. [methods] 1.Eighty-five plaques were selected from January 2013 to December 2013 in our hospital. There were 40 patients (male 21, female 19, mean age 57.3 鹵7.52). GE LOGIQE9 ultrasound was used with a linear 9L probe with a frequency of 5.0 ~ 9.0MHZ. Carotid plaques were examined by conventional ultrasound and elastic imaging, and two-dimensional gray-scale and elastic dynamic images of plaques were obtained. 3. According to the dynamic elastic maps of plaques, the elastic scores and elastic parameters of plaques were obtained. The patch GSM. 4 was obtained by computer aided program, and the patch was divided into four groups according to the classification scheme proposed by Gray-weale et al. The elastic scores of plaques in four groups were analyzed. The difference between elastic parameters and GSM. 5. The correlation between the elastic parameters of plaque and GSM of plaque was analyzed. [results] 1. The RTE pattern of plaque showed that homogeneous green was dominant in homogeneous hypoechoic plaque; Heterogeneous hypoechoic plaques were characterized by uneven green or irregular greenish-blue phases, and heterogeneous hyperechoic plaques were mainly blue or irregular blue-green patches. Homogeneous hyperechoic plaque showed blue. 2. Plaque elasticity score, elastic parameter and GSM group were compared: there was significant difference between homogeneous hypoechoic plaque group and heterogeneous hyperechoic plaque group and homogeneous hyperechoic plaque group (P0.05). There was significant difference between heterogeneous hypoechoic plaque and heterogeneous hyperechoic plaque group and homogeneous hyperechoic plaque group (P0.05). 3. The elastic hardness index of plaque was linearly correlated with GSM of plaque (r = 0.886P = 0.000). There was a linear relationship between the ratio of elastic hardness of plaque and the GSM of plaque (r = 0.810 / P = 0.000). [conclusion] 1. The RTE diagram with different gray scale plaques has different characteristics. 2. The elastic score and elastic parameters of plaque can reflect. The soft and hard degree of different gray-scale plaques. 3. The elastic parameters of plaques are linearly related to the GSM of plaques.
【學位授予單位】：福建醫(yī)科大學
【學位級別】：碩士
【學位授予年份】：2014
【分類號】：R445.1
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