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實(shí)時心臟磁共振成像左心室功能分析研究

發(fā)布時間:2018-08-06 17:10
【摘要】:實(shí)時自由呼吸心臟成像是一種重復(fù)性好、采集時間短且不需要屏氣的磁共振成像方法。然而實(shí)時心臟成像進(jìn)行左心室功能分析時,通常需要依靠人眼找出舒張末期和收縮末期圖像,這個過程非常費(fèi)時費(fèi)力。為了節(jié)省處理時間,本文提出一種半自動定位舒張末期和收縮末期圖像的方法。該方法主要通過對呼吸運(yùn)動信號進(jìn)行擬合,在擬合信號呼吸末期利用互相關(guān)系數(shù)確定舒張末期和收縮末期圖像。整個過程采集了10名健康志愿者實(shí)時心臟磁共振圖像,并同標(biāo)準(zhǔn)屏氣穩(wěn)態(tài)自由進(jìn)動序列采集數(shù)據(jù)進(jìn)行左心室功能分析比較。實(shí)驗(yàn)結(jié)果表明,所提方法能夠正確檢測出舒張末期和收縮末期圖像。未來,這個方法可望在臨床上進(jìn)行快速地左心室功能分析。
[Abstract]:Real-time free-breathing cardiac imaging is a kind of magnetic resonance imaging method with good repeatability, short acquisition time and no need to hold breath. However, the analysis of left ventricular function by real-time cardiac imaging usually depends on the human eye to identify the end-diastolic and end-systolic images, which is a time-consuming and laborious process. In order to save processing time, a semi-automatic method for locating end-diastolic and end-systolic images is proposed. In this method, the end diastolic and end systolic images are obtained by fitting the respiratory motion signals and determining the end diastolic and end systolic images by using the number of interrelation between the fitting signals and the end of respiration. Real time cardiac magnetic resonance imaging (Mr) images of 10 healthy volunteers were collected and compared with the data collected by standard breath-holding steady-state free precession sequence for left ventricular function analysis. The experimental results show that the proposed method can correctly detect end-diastolic and end-systolic images. In the future, this method is expected to rapidly analyze left ventricular function clinically.
【作者單位】: 貴州醫(yī)科大學(xué)生物與工程學(xué)院;中國科學(xué)院深圳先進(jìn)技術(shù)研究院;
【基金】:國家自然科學(xué)基金地區(qū)科學(xué)基金資助項(xiàng)目(81460206)
【分類號】:R445.2

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相關(guān)期刊論文 前10條

1 龐玉生,楊岳松,黃國英,陳張根,劉豫陽;小兒先天性心臟病的磁共振成像[J];臨床心血管病雜志;2001年07期

2 翟昭華;顳部病變的磁共振成像[J];放射學(xué)實(shí)踐;2001年02期

3 陳f,

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