【摘要】：第一部分應用左房追蹤技術探討正常人左房參數(shù)及影響因素 目的:應用左房追蹤技術探討正常人左房參數(shù)及其影響因素。 方法:選取202例正常人，其中男99例、女103例。男、女平均年齡分別為(41.5±12.5)歲、(44.9±13.1)歲，運用左房追蹤技術(left atrial tracking, LAT)獲得左房：最大上下徑(LALmax)、最小上下徑(LALmin)、最大周長(LACmax)、最小周長(LACmin)、最大面積(LAAmax)、最小面積(LAAmin)、最大容積(LAVmax)、最小容積(LAVmin)、收縮前容積(LApre)、收縮期充盈速率(dv/dtS)、左房舒張早期排空速率(dv/dtE)、左房舒張晚期排空速率(dv/dtA)參數(shù)的正常參考值范圍，并用體表面積(BSA)標化，研究其是否受性別、年齡因素影響。 結果:男性組與女性組比較，左房各參數(shù)均值差異無統(tǒng)計學意義(P㧐0.05)。左房各參數(shù)在不同年齡組之間差異具有統(tǒng)計學意義(P0.05)，各參數(shù)隨年齡的增長而增加。 結論:左房追蹤技術測得正常人左房各參數(shù)隨著年齡的增長而增大，但與性別無關，作為新技術在探討正常人左房構型及功能方面具有一定的可行性。 第二部分應用實時三維超聲心動圖對正常人左房功能相關參數(shù)的研究 目的：應用實時三維超聲心動圖（real-time three-dimensionalechocardiography,RT-3DE）探討正常人左房容積及功能相關參數(shù)的正常值及其應用價值。 方法：選取202例健康志愿者，按性別分為男性組和女性組，按年齡分為A組≤40歲(63例)，B組41～60歲（87例），C組㧐60歲（52例）。應用RT-3DE技術獲得左房最大容積（LAEDV）、左房最小容積（LAESV）、左房射血量（LASV）、左房收縮前容積（LApre）、左房被動排空容積（LAVp）、左房主動排空容積（LAVa）和左心房射血分數(shù)（LAEF），并對參數(shù)用體表面積校正,得出LAEDVI、LAESVI、LASVI、LApreI、LAVpI、LAVaI、LAEF’,統(tǒng)計分析得到上述參數(shù)正常值區(qū)間范圍，并比較各年齡組及性別組之間的差異。 結果：202例健康志愿者LAEDVI為（32.58～35.05）ml/m2，LAESVI為（14.80～16.21）ml/m2，LASVI為（17.87～19.40）ml/m2，LApreI為(17.99～19.86)ml/m2、LAVpI為(10.46～11.92)ml/m2、LAVaI為(6.88～7.92)ml/m2、LAEF’為（53.54～55.95）%。男性組與女性組比較LAEDVI、LAESVI、LASVI、LApreI、LAVpI、LAVaI、LAEF’值差異無統(tǒng)計學意義(P0.05)。不同年齡組間比較LAEDVI、LAESVI、LASVI、LApreI、LAVpI、LAVaI值差異有統(tǒng)計學意義(P0.05)，LAEF’值在各年齡組間呈遞減趨勢，但差異無統(tǒng)計學意義(P0.05)。結論：左房各參數(shù)值與性別無關，，LAEDVI、LAESVI、LASVI、LApreI、LAVpI、LAVaI隨年齡增加而增大，LAEF’不隨年齡變化。RT-3DE技術具有實時、動態(tài)、立體、準確、無創(chuàng)等優(yōu)點，在評價左房容積及功能方面是可行的，為臨床能夠正確評估左房功能提供了新方法。
[Abstract]:The first part was to study the parameters of left atrium and its influencing factors in normal subjects by using left atrial tracing technique. Objective: to explore the parameters of left atrium and its influencing factors by using the technique of left atrial tracing. Methods: 202 normal persons were selected, including 99 males and 103 females. The mean age of male and female were (41.5 鹵12.5) years and (44.9 鹵13.1) years, respectively. Using left atrial tracing technique (left atrial tracking, LAT) to obtain left atrium: maximum inferior and inferior diameter (LALmax), minimum upper and lower diameter (LALmin), maximum circumference (LACmax), minimum circumference (LACmin), maximum area minimum area (LAAmin), maximum volume (LAVmax), minimum volume (LAVmin), systolic volume (LApre), systolic filling The normal reference range of the parameters of left atrial early diastolic emptying rate (dv/dtE), left atrial late diastolic emptying rate (dv/dtA), left atrial velocity (dv/dtS), left atrial early diastolic velocity (dv/dtE), left atrial late diastolic velocity (dv/dtA), The body surface area (BSA) was standardized to study whether it was affected by sex and age. Results: there was no significant difference in the mean values of left atrial parameters between male group and female group (P 0.05). The parameters of left atrium were significantly different among different age groups (P0.05), and the parameters increased with the increase of age. Conclusion: the parameters of left atrium in normal subjects increased with age, but not related to sex. As a new technique, it is feasible to study the configuration and function of left atrium in normal subjects. Part two: study on parameters related to left atrial function in normal subjects by real-time three-dimensional echocardiography objective: to explore the normal parameters of left atrial volume and function in normal subjects by using real-time three-dimensional echocardiography RT-3DE Value and its application value. Methods: 202 healthy volunteers were divided into male group and female group according to sex, and divided into group A 鈮

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