【摘要】：目的探討血管回聲追蹤技術(shù)(Echo-Tracking, ET)檢測高尿酸血癥患者及高尿酸合并高脂血癥患者早期頸總動脈彈性功能改變的臨床應(yīng)用價值。 方法應(yīng)用ET技術(shù)對60例正常對照組、60例單純高尿酸血癥患者(A組)、60例高尿酸合并高脂血癥患者(B組)頸總動脈的僵硬度指數(shù)(β)、血管壓力-應(yīng)變彈性系數(shù)(Ep、順應(yīng)性(AC)、擴(kuò)張指數(shù)(AI)及脈搏波傳導(dǎo)速度(PWV β)進(jìn)行檢測,對各組間所得數(shù)據(jù)進(jìn)行統(tǒng)計(jì)分析。 結(jié)果①各組間常規(guī)超聲測量結(jié)果比較：各組間IMT、SPV及RI差異均無統(tǒng)計(jì)學(xué)意義；②各組間頸總動脈彈性參數(shù)比較：與對照組比較,A組及B組患者β、Ep、PWV β、AI均明顯增高(P0.05),而AC則明顯減低(P0.05)；與A組比較,B組患者β、Ep、PWV β、AI均明顯增高、AC則明顯降低(P0.05)。 結(jié)論ET技術(shù)能較早發(fā)現(xiàn)高尿酸血癥及高尿酸合并高血脂患者頸總動脈彈性改變,為臨床早期診斷與治療動脈粥樣硬化性病變提供重要依據(jù)。
[Abstract]:Objective to evaluate the clinical value of Echo-Trackingtechnique (et) in detecting the early changes of common carotid artery elasticity in patients with hyperuricemia and hyperuricemia combined with hyperlipidemia. Methods the common carotid artery stiffness index (尾), vascular pressure-strain elasticity coefficient (Epp, compliance) of 60 patients with hyperuricemia (group A) and 60 patients with hyperuricemia (group B) were studied by et technique. (AC), expansion index (AI) and pulse wave velocity (PWV 尾) were measured. The data obtained from each group were statistically analyzed. Results 1 comparison of the results of routine ultrasound measurement among groups: there was no significant difference in SPV and RI between each group; 2Comparison of the elastic parameters of common carotid artery: compared with the control group, the 尾 -Epp PWV 尾 -AI in group A and group B were significantly increased (P0.05), but AC was significantly decreased (P0.05), while in group B, 尾 -EpPWV 尾 -AI was significantly increased (P0.05), while that in group B was significantly lower than that in group A (P0.05). Conclusion et technique can detect early changes of carotid elasticity in patients with hyperuricemia and hyperuricemia combined with hyperlipidemia, which provides important basis for early diagnosis and treatment of atherosclerotic lesions.
【學(xué)位授予單位】：青島大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2014
【分類號】：R589.7;R445.1

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