本文選題：可逆性胼胝體壓部病變綜合征 + 磁共振成像　； 參考：《臨床兒科雜志》2015年11期

【摘要】：目的探討兒童可逆性胼胝體壓部病變綜合征(RESLES)的臨床及影像學(xué)特征。方法回顧性分析2011年12月至2015年5月收治的11例RESLES兒童,對其病因、臨床表現(xiàn)、影像學(xué)資料、治療及隨訪進(jìn)行總結(jié)分析。結(jié)果11例患兒中男7例、女4例,年齡(6.24±1.41)歲(8個(gè)月~11歲),1型RESLES 8例、2型RESLES 3例。最常見的病因?yàn)轶@厥發(fā)作和感染。除原發(fā)病表現(xiàn),意識障礙是突出的臨床表現(xiàn),其余神經(jīng)系統(tǒng)表現(xiàn)均輕微或無。8例1型RESLES患兒頭顱磁共振(MRI)顯示胼胝體壓部橢圓形病灶,3例2型RESLES患兒顯示整個(gè)胼胝體、側(cè)腦室周圍及半卵圓中心白質(zhì)廣泛受累,病灶特征為T1WI等或低信號,T2WI、FLAIR像、DWI高信號,ADC低信號。所有患兒復(fù)查時(shí)(間隔4~30 d)原有病灶均完全消失。隨訪2個(gè)月~3年6個(gè)月,頭顱MRI均正常。結(jié)論兒童RESLES病因復(fù)雜,臨床表現(xiàn)無特異性,診斷主要依賴頭顱MRI,尤其是DWI序列,突出特征為胼胝體壓部伴或不伴雙側(cè)腦白質(zhì)的對稱性高信號。RESLES預(yù)后良好,應(yīng)避免過度治療。
[Abstract]:Objective to investigate the clinical and imaging features of reversible corpus callosum syndrome (RESLES) in children. Methods a retrospective analysis of 11 children with RESLES from December 2011 to May 2015 was reviewed. The causes, clinical manifestations, imaging data, treatment and follow-up were analyzed. Results of the 11 children, 7 cases, 4 women, and age (6.24 + 1.41). Age (8 months ~11 years), type 1 RESLES 8, type 2 RESLES 3. The most common disease was convulsive seizures and infection. Except for the original manifestation, the consciousness disorder was a prominent clinical manifestation, the rest of the nervous system showed slight or no.8 cases of RESLES children's head magnetic resonance (MRI) display of the corpus callosum pressure oval focus, 3 cases of 2 type RESLES children showed the whole The corpus callosum, the lateral ventricle and the central white matter in the center of the oval center were widely involved. The lesion was characterized by T1WI or low signal, T2WI, FLAIR image, DWI high signal and ADC low signal. All the children were completely disappeared during the reexamination (interval 4~30 d). The follow-up of 2 months ~3 years and 6 months was normal. Conclusion the etiology of RESLES in children is complex and the clinical manifestations are not specific. The diagnosis mainly depends on the head MRI, especially the DWI sequence, and the prognosis is good for the symmetrical high signal.RESLES characterized by the corpus callosum pressure with or without bilateral white matter, and should avoid overtreatment.
【作者單位】： 山東大學(xué)附屬省立醫(yī)院小兒神經(jīng)科;
【分類號】：R741;R445.2

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