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速度向量成像評價高血壓患者頸動脈粥樣硬化斑塊穩(wěn)定性的研究

發(fā)布時間:2018-07-02 23:41

  本文選題:超聲 + 速度向量成像技術(shù); 參考:《青島大學(xué)》2014年碩士論文


【摘要】:目的應(yīng)用速度向量成像技術(shù)比較高血壓患者與非高血壓患者頸總動脈粥樣硬化斑塊運(yùn)動特性及斑塊力學(xué)特點(diǎn),探討高血壓患者與非高血壓患者的頸動脈斑塊穩(wěn)定性是否存在差異。 方法回顧性分析93例頸動脈粥樣硬化斑塊患者的速度向量成像資料,其中51例患者伴有原發(fā)性高血壓,其余42例患者血壓正常,應(yīng)用速度向量成像(VVI)技術(shù)檢測頸總動脈粥樣硬化斑塊基底部、肩部、纖維帽頂部的運(yùn)動速度、應(yīng)變率,利用卡方檢驗分組進(jìn)行比較分析。 結(jié)果51例高血壓組患者共檢出75處粥樣硬化斑塊,其中52處硬斑塊,23處軟斑塊,42例非高高血壓組患者共檢出56處粥樣硬化斑塊,其中39處硬斑塊,17處軟斑塊,高血壓組頸動脈軟斑塊肩部近心端、頂部收縮期最大運(yùn)動速度、最大應(yīng)變率高于非高血壓組,差異有統(tǒng)計學(xué)意義(P0.05或P0.01),而軟斑塊肩部遠(yuǎn)心端、基底部收縮期最大運(yùn)動速度、最大應(yīng)變率與非高血壓組比較差別無明顯統(tǒng)計學(xué)意義(P0.05);高血壓組頸動脈硬斑塊肩部近心端、遠(yuǎn)心端、頂部、基底部收縮期最大運(yùn)動速度、最大應(yīng)變率略高于非高血壓組,差異無明顯統(tǒng)計學(xué)意義(P0.05)。 結(jié)論速度向量成像技術(shù)可用于高血壓患者頸動脈粥樣硬化斑塊及斑塊不同部位運(yùn)動速度、應(yīng)變及應(yīng)變率的分析,為評價斑塊穩(wěn)定性提供新的方法;高血壓患者頸動脈軟斑塊穩(wěn)定性低于非血壓患壓患者,而硬斑塊穩(wěn)定性兩組患者差別不明顯。
[Abstract]:Objective to compare the motion and mechanical characteristics of carotid atherosclerotic plaques between hypertensive patients and non-hypertensive patients by velocity vector imaging. To investigate whether carotid plaque stability is different between hypertensive patients and non-hypertensive patients. Methods the velocity-vector imaging data of 93 patients with carotid atherosclerotic plaque were analyzed retrospectively. Among them, 51 cases were accompanied with essential hypertension, and 42 cases had normal blood pressure. Velocity vector imaging (VVI) technique was used to detect the velocity and strain rate of carotid atherosclerotic plaques at the base, shoulder and top of the fibrous cap. The chi-square test was used to compare and analyze the velocity and strain rate of carotid atherosclerotic plaques. Results Seventy-five atherosclerotic plaques were detected in 51 patients with hypertension, including 52 hard plaques, 23 soft plaques, 42 non-hypertensives, 56 atherosclerotic plaques, 39 hard plaques and 17 soft plaques. In the hypertension group, the maximum systolic velocity and strain rate at the top of the shoulder were significantly higher than those in the non-hypertensive group (P0.05 or P0.01), while the maximal systolic velocity in the distal shoulder and the base of the soft plaque was higher than that in the non-hypertensive group (P0.05 or P0.01). There was no significant difference between the maximum strain rate and the non-hypertension group (P0.05). The maximum systolic velocity of the shoulder, distal end, top and base of the carotid artery hard plaque in the hypertension group was slightly higher than that in the non-hypertension group, and the maximum strain rate was higher than that in the non-hypertension group. The difference was not statistically significant (P0.05). Conclusion Velocity vector imaging can be used to analyze the velocity, strain and strain rate of carotid atherosclerotic plaques and different parts of plaque in hypertensive patients, which provides a new method for evaluating plaque stability. The stability of carotid soft plaque in hypertensive patients was lower than that in patients without blood pressure, but there was no significant difference in the stability of hard plaques between the two groups.
【學(xué)位授予單位】:青島大學(xué)
【學(xué)位級別】:碩士
【學(xué)位授予年份】:2014
【分類號】:R544.1;R543.4;R445.1

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