本文選題：GTV-T體積 + 臨床分期　； 參考：《腫瘤防治研究》2015年07期

【摘要】：目的探討應(yīng)用腫瘤體積大小評價食管癌臨床分期標準的準確性、符合程度及其與預(yù)后的關(guān)系。方法分析接受根治性三維適形放療(three-dimensional conformal radiotherapy,3DCRT)的375例食管癌患者臨床資料,選擇合適的GTV-T體積分級標準,結(jié)合區(qū)域淋巴結(jié)轉(zhuǎn)移情況進行臨床分期,并結(jié)合患者預(yù)后進行分析。結(jié)果與病理T分期對應(yīng),將GTV-T體積按≤30 cm3、30~≤60 cm3、60~90cm3、90 cm3分為T1、T2、T3、T4四級,5年生存率之間比較,T3與T4級之間差異無統(tǒng)計學(xué)意義(P=0.556),而按T1、T2、T3+4三分級,各T分級之間的生存差異有統(tǒng)計學(xué)意義(P0.001)。無區(qū)域淋巴結(jié)轉(zhuǎn)移N0者較有區(qū)域或非區(qū)域淋巴結(jié)轉(zhuǎn)移N1~2者預(yù)后好(P=0.000)。對應(yīng)GTV-T體積T1、T2、T3+4三分級,將食管癌臨床分期對應(yīng)分為Ⅰ、Ⅱ、Ⅲ期,將出現(xiàn)N2期或遠處轉(zhuǎn)移的患者,全部歸入Ⅳ期,各期生存差異具有統(tǒng)計學(xué)意義(P0.001)。結(jié)論 GTV-T按T1、T2、T3+4三分級法能較好地反映預(yù)后生存;對應(yīng)GTV-T三分級的臨床四分期法,亦能較好的反應(yīng)預(yù)后。
[Abstract]:Objective to evaluate the accuracy, degree of coincidence and prognosis of clinical staging criteria for esophageal carcinoma by using tumor volume. Methods the clinical data of 375 patients with esophageal carcinoma receiving three-dimensional conformal radiotherapymetric 3DCRT were analyzed. The appropriate GTV-T volumetric grading criteria were selected and the clinical staging was performed in combination with regional lymph node metastasis and the prognosis of the patients was analyzed. Results according to pathological T stage, GTV-T volume was divided into T _ 1 T _ 2 and T _ 3 ~ T _ 4 grade according to 鈮，

本文編號：2065542