本文選題：放射性核素 + 納米系統(tǒng)��； 參考：《東南大學學報(醫(yī)學版)》2017年06期

【摘要】：隨著納米技術(shù)和分子影像學的發(fā)展,多功能納米載體系統(tǒng)響應(yīng)了目前臨床醫(yī)學以及基礎(chǔ)醫(yī)學的需求。白蛋白納米載體、脂質(zhì)體納米載體、磁性材料納米載體以及碳納米載體等是目前研究的較多的納米載體。將放射性核素與多功能納米載體相結(jié)合,利用納米載體的粒徑小、緩釋性以及表面可修飾性等特點可將放射性核素本身的治療效果發(fā)揮至最佳。不僅可以減少放射性核素的毒副作用,而且可以提高放射性核素的治療效率和靶向濃度。以納米技術(shù)為核心,將生物醫(yī)學治療和分子影像學相結(jié)合的診斷治療一體化新模式將成為未來臨床醫(yī)學發(fā)展的新思路。
[Abstract]:With the development of nanotechnology and molecular imaging, multifunctional nano-carrier system has responded to the needs of clinical medicine and basic medicine. Albumin nano-carriers, liposome nano-carriers, magnetic nano-carriers and carbon nano-carriers are more and more researched nanomaterials. By combining radionuclides with multi-functional nano-carriers, the therapeutic effects of radionuclides themselves can be optimized by using the characteristics of small particle size, slow release and surface modification of nano-carriers. It can not only reduce the toxic side effects of radionuclides, but also improve the therapeutic efficiency and target concentration of radionuclides. The integration of biomedical therapy and molecular imaging will be a new approach to the development of clinical medicine in the future with nanotechnology as the core.
【作者單位】： 南京中醫(yī)藥大學附屬醫(yī)院核醫(yī)學科;
【基金】：江蘇省自然科學基金資助項目(BK20131455)
【分類號】：R730.44
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本文編號：1990119