孕中晚期胎兒小腦形態(tài)發(fā)育的MRI研究
發(fā)布時間:2018-06-06 17:09
本文選題:胎兒 + 小腦。 參考:《中國臨床解剖學(xué)雜志》2015年04期
【摘要】:目的應(yīng)用胎兒標(biāo)本MR圖像觀察14~40周胎兒小腦結(jié)構(gòu)發(fā)育情況。方法 87例無中樞神經(jīng)系統(tǒng)疾病的胎兒,孕齡為14~40周,行3.0T磁共振掃描,根據(jù)所得橫矢冠圖像分析小腦各結(jié)構(gòu)發(fā)育情況。結(jié)果 T2WI圖像觀察可見各結(jié)構(gòu)出現(xiàn)時間不同:16周時可見齒狀核,17周時被蓋-小腦蚓角閉合,20周時原裂出現(xiàn),22周時錐體前裂,第四腦室顯示清晰,24周時次裂,后外側(cè)裂出現(xiàn)。孕晚期,小腦體積增長迅速,前后葉比例由大變小。結(jié)論 3.0T磁共振圖像可以較清晰地顯示孕中后期胎兒小腦各結(jié)構(gòu)的發(fā)育情況,以此為依據(jù)可為臨床宮內(nèi)胎兒小腦發(fā)育狀況的診斷與評估提供解剖和影像學(xué)依據(jù)。
[Abstract]:Objective to observe the development of cerebellar structure of the fetus at 14 ~ 40 weeks by using Mr images of fetal specimen. Methods Eighty-seven fetuses without central nervous system disease were examined with 3.0T magnetic resonance imaging at the gestational age of 14 ~ 40 weeks. The development of cerebellar structures was analyzed according to the obtained transverse sagittal coronal images. Results on T _ 2WI images, it was found that the dentate nucleus could be seen at 17 weeks after the closure of the tegmental-cerebellar vermis angle at different times of time on T _ 2WI images. The anterior pyramidal fissure appeared at 20 weeks after closure of the vermis angle of the cerebellum, the second fissure at 24 weeks and the posterolateral fissure on the fourth ventricle. In the third trimester of pregnancy, the cerebellar volume increased rapidly and the ratio of anterior and posterior lobes changed from large to small. Conclusion 3.0T magnetic resonance imaging can clearly display the development of fetal cerebellar structures in the middle and late pregnancy, which can provide anatomic and imaging basis for the diagnosis and evaluation of fetal cerebellar development in the clinic.
【作者單位】: 濱州醫(yī)學(xué)院人體解剖學(xué)教研室;山東大學(xué)醫(yī)學(xué)院斷層影像解剖學(xué)研究中心;
【基金】:濱州醫(yī)學(xué)院科技計劃(BY2011KJ083)
【分類號】:R714.5;R445.2
【共引文獻】
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