本文選題：經(jīng)直腸超聲造影 + 經(jīng)直腸彩色多普勒超聲��； 參考：《新疆醫(yī)科大學》2014年碩士論文

【摘要】：目的：探討經(jīng)直腸超聲造影和彩色多普勒超聲在經(jīng)直腸灰階超聲引導前列腺穿刺活檢應用價值對較。方法：選取2012年10月至2013年11月我院泌尿中心85例灰階超聲未檢測出前列腺癌可疑病灶,實驗室檢查懷疑前列腺癌患者的臨床資料,38例病例術(shù)前行經(jīng)直腸超聲造影,47例病例術(shù)前行經(jīng)直腸彩色多普勒,對超聲聲像顯像可疑病灶靶向行經(jīng)直腸前列腺12點穿刺活檢,分別比較兩組組前列腺穿刺效能。結(jié)果：CEUS組靶向引導檢測出前列腺癌陽性穿刺針數(shù)敏感性、陰性預測值較CDFI組高(P0.05)；特異性、陽性預測值兩組差異無統(tǒng)計學意義(P0.05)。在PSA30ng/ml組中,兩組間比較CEUS組敏感性CDFI組高(P0.05)；兩組間特異性、陽性預測值和陰性預測值統(tǒng)計學無明顯差異(P0.05)。在PSA30ng/ml組中兩組間比較CEUS組敏感性、陰性預測值較CDFI組高(P0.05),特異性、陽性預測值差異無統(tǒng)計學意義(p0.05)o CEUS組穿刺陽性針Gleason評分9.03±0.751分較CDFI組8.72±0.690分高(P0.05),兩組間術(shù)后并發(fā)癥差異無統(tǒng)計學意義(P0.05)。結(jié)論：經(jīng)直腸CEUS靶向引導前列腺穿刺活檢較CDFI提高了穿刺點陽性針敏感性、陰性預測值,能避免不必要區(qū)域的穿刺；PSA30ng/ml病例中,經(jīng)直腸TRUS靶向引導前列腺穿刺活檢較經(jīng)直腸CDFI提高陰性預測值,能避免不必要區(qū)域的穿刺；經(jīng)直腸TRUS靶向引導前列腺穿刺活檢陽性針較CDFI在Gleason4+3評分組中Gleason評分較高,能發(fā)現(xiàn)Gleason評分較高的前列腺癌。
[Abstract]:Objective: to evaluate the value of transrectal ultrasonography and color Doppler ultrasound in transrectal gray scale ultrasound guided prostate biopsy. Methods: from October 2012 to November 2013, 85 cases of suspected prostate cancer lesions were detected by gray scale ultrasonography in our urinary center. Clinical data of 38 patients suspected of Prostate Cancer before operation 47 patients with transrectal contrast-enhanced ultrasonography underwent transrectal color Doppler sonography and targeted transrectal biopsy of the prostate at 12:00. The efficacy of prostate puncture was compared between the two groups. Results the sensitivity of positive puncture needle number of prostate cancer was detected by targeting guidance in the group of: CEUS, and the negative predictive value was higher than that in the group of CDFI (P 0.05), but there was no significant difference between the two groups in specificity and positive predictive value (P 0.05). In PSA30ng/ml group, there was no significant difference in specificity, positive predictive value and negative predictive value between the two groups compared with CEUS group (P 0.05), the sensitivity of CEUS group was higher than that of CDFI group (P 0.05), and there was no significant difference between the two groups in terms of specificity, positive predictive value and negative predictive value. In PSA30ng/ml group, the sensitivity of CEUS group was higher than that of CDFI group, and the negative predictive value was higher than that of CDFI group. There was no significant difference in the positive predictive value between the two groups. The Gleason score of the puncture positive needle was 9.03 鹵0.751in the CEUS group, which was higher than that in the CDFI group (8.72 鹵0.690). There was no significant difference in postoperative complications between the two groups (P 0.05). Conclusion: compared with CDFI, transrectal CEUS targeted guided prostate biopsy can improve the sensitivity and negative predictive value of positive needle, and can avoid the unnecessary area of PSA30ng / ml cases. The negative predictive value of transrectal TRUS targeted guided prostate biopsy was higher than that of transrectal CDFI, and the puncture in unnecessary area could be avoided. The positive needle of transrectal TRUS targeted guided prostate biopsy was higher than that of CDFI in Gleason4 3 score group. Prostate cancer with high Gleason score can be found.
【學位授予單位】：新疆醫(yī)科大學
【學位級別】：碩士
【學位授予年份】：2014
【分類號】：R445.1

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