本文選題：磁共振 + 彌散加權(quán)成像��； 參考：《中國(guó)矯形外科雜志》2015年07期

【摘要】：[目的]探討磁共振DWI、DCE序列對(duì)評(píng)價(jià)中西醫(yī)結(jié)合治療早期強(qiáng)直性脊柱炎療效的應(yīng)用價(jià)值。[方法]隨訪前期研究中的48例(男38例、女10例)確診為早期AS并經(jīng)中西醫(yī)治療的患者,通過(guò)磁共振DWI及DCE掃描,獲取治療后關(guān)節(jié)面下骨髓ADC平均值,繪制TIC曲線,計(jì)算Fenh、Senh值及達(dá)峰時(shí)間Tmax值,與前期研究所獲取治療前相應(yīng)數(shù)據(jù)進(jìn)行統(tǒng)計(jì)學(xué)分析比對(duì)。[結(jié)果]經(jīng)臨床治療的患者骶髂關(guān)節(jié)面下骨髓區(qū)ADC平均值:髂骨側(cè)為(4.34±0.55)×10-4mm2/s,骶骨側(cè)為(3.96±0.23)×10-4mm2/s,均較治療前減低,組間差距具有顯著統(tǒng)計(jì)學(xué)意義。半定量指標(biāo)Fenh、Senh均較對(duì)照組明顯減低,Tmax高于對(duì)照組,差異具有統(tǒng)計(jì)學(xué)意義。骶髂關(guān)節(jié)骶、髂側(cè)ADC值與Fenh值間呈高度正相關(guān)關(guān)系(P0.05),髂側(cè)ADC值與Senh呈高度正相關(guān)關(guān)系(P0.05)。[結(jié)論]磁共振DWI及DCE序列可用于評(píng)價(jià)AS炎癥活動(dòng)程度變化,反映早期AS患者的治療療效,并可為臨床療效提供可靠的影像學(xué)依據(jù)。
[Abstract]:[objective] to evaluate the clinical value of DWI DCE sequence in the treatment of early ankylosing spondylitis (ankylosing spondylitis). [methods] 48 patients (38 males and 10 females) who were diagnosed as early and were treated with traditional Chinese and western medicine were studied in the early follow-up study. The mean value of ADC in bone marrow of articular surface after treatment was obtained by DWI and DCE scanning, and TIC curve was drawn. The Senh value and peak time (Tmax) were calculated and compared with the corresponding data before treatment. [results] the average value of ADC in the subarticular surface of sacroiliac bone marrow was 4.34 鹵0.55 脳 10 ~ (-4) mm ~ (-2) / s in the iliac side and 3.96 鹵0.23 脳 10 ~ (-4) mm ~ (2 / s) in the sacral side. The difference between the two groups was statistically significant. Compared with the control group, the semi-quantitative index Fenhn Senh was significantly lower than that of the control group, and the difference was statistically significant. In sacroiliac joint, there was a high positive correlation between ADC and Fenh in sacroiliac joint (P 0.05), and a high positive correlation between ADC (P 0.05) and Senh (P 0.05). [conclusion] MRI DWI and DCE sequences can be used to evaluate the changes of inflammatory activity of as, to reflect the therapeutic effect of early as patients, and to provide reliable imaging evidence for clinical efficacy.
【作者單位】： 泰山醫(yī)學(xué)院附屬醫(yī)院影像科;
【基金】：山東省衛(wèi)生廳醫(yī)藥衛(wèi)生科技發(fā)展計(jì)劃項(xiàng)目(編號(hào):2013WS0325)
【分類號(hào)】：R593.23;R445.2

【參考文獻(xiàn)】

相關(guān)期刊論文 前1條

1 趙周社;辛軍;郭啟勇;王爽;陸U，

本文編號(hào)：1928226