肺浸潤性黏液腺癌的影像表現(xiàn)與病理對照
本文選題:肺浸潤性黏液腺癌 + 體層攝影術(shù)。 參考:《臨床放射學(xué)雜志》2017年09期
【摘要】:目的探討肺浸潤性黏液腺癌(PIMA)的CT和PET-CT表現(xiàn)及其病理特點。方法回顧性分析經(jīng)手術(shù)病理或穿刺活檢證實的26例PIMA患者的臨床、影像及病理資料。26例患者均行CT平掃,其中23例行CT多期增強(qiáng)掃描;10例行PET-CT檢查。觀察其影像學(xué)表現(xiàn)并與病理進(jìn)行對照。結(jié)果 26例PIMA中,單發(fā)結(jié)節(jié)或腫塊19例,單發(fā)實變2例,多發(fā)結(jié)節(jié)或混合型5例。病灶最大徑范圍0.8~27.7 cm,平均(4.83±5.18)cm。病灶密度較低[平均(24.9±14.89)HU],增強(qiáng)后多呈輕中度強(qiáng)化。邊緣光滑16例,分葉征16例,毛刺征8例,不完整暈征13例,空泡或假性空洞征8例,血管造影征3例,"衛(wèi)星瘤"征1例,鈣化2例。10例病灶氟代脫氧葡萄糖(FDG)攝取均明顯增高,標(biāo)準(zhǔn)攝取量(SUV)最大值為2.5~16.5,平均8.31±4.88。26例均診斷為PIMA,鏡下腫瘤細(xì)胞沿肺泡壁生長,呈黏液柱狀,胞漿豐富,間質(zhì)可見黏液形成,部分腺腔內(nèi)可見黏液聚集。結(jié)論 PIMA的影像表現(xiàn)有一定的特征,CT平掃密度較低,病灶出現(xiàn)不完整暈征及暈環(huán)內(nèi)間隔增厚、多發(fā)空泡征或假性空洞征、"衛(wèi)星瘤"灶,增強(qiáng)后呈輕中度強(qiáng)化,有助于PIMA的診斷。
[Abstract]:Objective to investigate the CT and PET-CT features of pulmonary invasive mucinous adenocarcinoma (PIMA). Methods 26 cases of PIMA confirmed by operation and pathology were retrospectively analyzed. All the 26 cases underwent plain CT scan, and 23 cases were examined by multiphase enhanced CT scan and 10 cases by PET-CT. The imaging findings were observed and compared with pathology. Results in 26 cases of PIMA, 19 cases were single nodules or masses, 2 cases were single consolidation, 5 cases were multiple nodules or mixed type. The maximum diameter of the lesion was 0.827. 7 cm (mean 4.83 鹵5.18 cm). The density of lesions was low [mean 24.9 鹵14.89)HU], and most of them showed mild and moderate enhancement after enhancement. The margin was smooth in 16 cases, lobular sign in 16 cases, burr sign in 8 cases, incomplete halo sign in 13 cases, vacuole or pseudocavity sign in 8 cases, angiography sign in 3 cases, and "satellite tumor" sign in 1 case. The uptake of fluorodeoxyglucose (FDG) was significantly increased in 2 cases and 10 cases of calcification. The maximum value of standard uptake of suv was 2.5 鹵16.5, with an average of 8.31 鹵4.88.26 cases diagnosed as PIMA. The tumor cells grew along the alveolar wall under microscope, showing mucus columnar, rich cytoplasm and mucus formation. Mucus aggregation could be seen in part of the glandular cavity. Conclusion the imaging features of PIMA are low density of plain CT scan, incomplete halo sign and thickening of the interval in halo ring, multiple cavitation sign or pseudo-cavitation sign, and "satellite tumor", which is helpful for the diagnosis of PIMA.
【作者單位】: 廣州醫(yī)科大學(xué)附屬第一醫(yī)院放射科;廣州醫(yī)科大學(xué)附屬第一醫(yī)院病理科;廣州醫(yī)科大學(xué)附屬第一醫(yī)院廣州呼吸疾病研究所胸外科;
【分類號】:R730.44;R734.2
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