本文選題：肺癌 + 近期療效　； 參考：《中國(guó)老年學(xué)雜志》2017年19期

【摘要】：目的探討CT灌注聯(lián)合能譜成像對(duì)老年射頻消融肺癌術(shù)后患者近期療效的。方法 60例經(jīng)病理證實(shí)的老年肺癌患者,均行射頻消融術(shù)治療,并于術(shù)前及術(shù)后行CT灌注聯(lián)合能譜成像檢查,比較手術(shù)前后CT灌注參數(shù)值及能譜CT參數(shù)值變化,并對(duì)比治療后緩解、復(fù)發(fā)者CT灌注參數(shù)值及能譜CT參數(shù)值。結(jié)果治療后CT灌注參數(shù)血流量(BF)、血容量(BV)、表面通透性(PS)均低于治療前(P0.05);能譜CT參數(shù)碘含量均低于治療前(P0.05);緩解組CT灌注參數(shù)BF、BV、PS均低于復(fù)發(fā)組(P0.05);緩解組能譜CT參數(shù)碘含量、水含量、CT值均低于復(fù)發(fā)組(P0.05)。結(jié)論 CT灌注聯(lián)合能譜成像能夠客觀反映老年肺癌射頻消融術(shù)治療前后病灶的灌注程度及血功特點(diǎn),進(jìn)而為平均射頻消融術(shù)的早期療效提供有利依據(jù)。
[Abstract]:Objective to investigate the short-term effect of CT perfusion combined with energy spectrum imaging on elderly patients with lung cancer after radiofrequency ablation. Methods 60 elderly patients with lung cancer confirmed by pathology were treated with radiofrequency ablation. Ct perfusion combined with energy spectrum imaging was performed before and after operation. The changes of CT perfusion parameters and energy dispersive CT parameters were compared before and after operation. The values of CT perfusion parameters and energy spectrum CT parameters in patients with remission and recurrence were compared. Results after treatment, the blood flow volume, blood volume and surface permeability of CT perfusion parameters were lower than that of pre-treatment (P 0.05), the iodine content of energy dispersive CT parameters were lower than that of P0.05, the CT perfusion parameters of remission group were lower than that of relapse group (P 0.05), the iodine content of energy spectrum CT parameters in remission group was lower than that in relapse group. The CT value of water content was lower than that of recurrence group (P 0.05). Conclusion CT perfusion combined with energy spectrum imaging can objectively reflect the degree of focus perfusion and blood work characteristics before and after radiofrequency ablation of lung cancer in the elderly and provide a favorable basis for the early curative effect of the average radiofrequency ablation.
【作者單位】： 海南醫(yī)學(xué)院第二附屬醫(yī)院放射科;
【基金】：海南省自然科學(xué)基金(No.811206)
【分類號(hào)】：R730.44;R734.2

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