本文選題：四維自動(dòng)左室定量分析技術(shù) + 青年肥胖��； 參考：《廣西中醫(yī)藥大學(xué)》2017年碩士論文

【摘要】：目的:應(yīng)用四維自動(dòng)左室定量分析技術(shù)(4-Dimensional auto left ventricular quantification,4D-LVQ)對青年肥胖型高血壓患者定量分析左心室收縮功能,探討4D-LVQ對評估青年肥胖型高血壓患者左心室收縮功能改變的應(yīng)用價(jià)值。方法:選取青年肥胖型高血壓患者組30例,青年高血壓患者組30例,正常青年組30例,共90例,三組實(shí)驗(yàn)組。采集經(jīng)胸標(biāo)準(zhǔn)清晰的心尖四腔心切面得四維全容積圖像數(shù)據(jù)并存儲,并應(yīng)用4D-LVQ軟件在線分析左心室不同水平及整體軸向收縮峰值應(yīng)變(longtiudinal peak strain,LS)、環(huán)向收縮峰值應(yīng)變(circumferential peak strain,CS)、徑向收縮峰值應(yīng)變(radial peak strain,RS)及面積收縮峰值應(yīng)變(area peak strain,AS)的牛眼圖,并對比這三組人群的應(yīng)變情況。結(jié)果:1.與正常青年組比較,青年高血壓患者組RS值中乳頭肌水平、心尖水平、心尖部及整體水平升高(p0.05)。其余節(jié)段水平不同應(yīng)變值兩組比較差異無統(tǒng)計(jì)學(xué)意義。2.與正常青年組比較,青年肥胖型高血壓患者組LS值中二尖瓣水平、乳頭肌水平及整體水平降低(p0.05);CS值中二尖瓣水平、心尖部及整體水平降低(p0.05);RS值中二尖瓣水平、乳頭肌水平、心尖水平、心尖部及整體水平降低(p0.05);AS值中二尖瓣水平、乳頭肌水平、心尖部及整體水平降低(p0.05)。其余節(jié)段水平不同應(yīng)變值兩組比較差異無統(tǒng)計(jì)學(xué)意義。3.與青年高血壓患者組比較,青年肥胖型高血壓患者組LS值中二尖瓣水平、乳頭肌水平、心尖水平及整體水平降低(p0.05);CS值中二尖瓣水平、心尖水平、心尖部及整體水平降低(p0.05);RS值中二尖瓣水平、乳頭肌水平、心尖部及整體水平降低(p0.05);AS值中二尖瓣水平、心尖部及整體水平降低(p0.05)。其余節(jié)段水平不同應(yīng)變值兩組比較差異無統(tǒng)計(jì)學(xué)意義。結(jié)論:青年肥胖型高血壓組患者早期LVEF處于正常范圍時(shí)已出現(xiàn)左心室收縮功能降低。4D-LVQ技術(shù)能客觀、定量、全面地評估左心室整體及局部心肌功能,可作為臨床評價(jià)早期心功能異常的參考指標(biāo)。
[Abstract]:Objective: to evaluate the value of 4-dimensional auto left ventricular quantification4D-LVQ in evaluating the left ventricular systolic function in young obese hypertensive patients by using four-dimensional automatic left ventricular quantitative analysis (4-dimensional auto left ventricular quantification4D-LVQs), and to evaluate the value of 4D-LVQ in evaluating the changes of left ventricular systolic function in young obese hypertensive patients. Methods: thirty young obese hypertension patients, 30 young hypertension patients and 30 normal young people were selected. The four-dimensional full-volume image data were collected and stored from the standard quadrilateral section of the heart through the chest. 4D-LVQ software was used to analyze the longitudinal peak strain of left ventricle at different levels and the whole axial contraction peak strain, circumferential peak strain, radial peak strain and area peak contraction strain area peak strainas. The response of the three groups was compared. The result is 1: 1. Compared with the normal young group, the levels of papillary muscle, apical, apical and whole heart were increased in the young hypertensive group (P 0.05). There was no significant difference between the two groups in the level of other segments, different strain values. 2. 2. Compared with the normal young group, the mitral valve level, the papillary muscle level and the whole level of mitral valve, mitral valve and papillary muscle were decreased in the young obese hypertension group, and the mitral valve level and the papillary muscle level were decreased in the apical region and the whole heart, and the middle mitral valve level and the papillary muscle level in the middle mitral valve value and the papillary muscle value were decreased in the apical part and the whole heart. The level of mitral valve, the level of papillary muscle, the apical part and the whole level of mitral valve, papillary muscle, apical part and whole were decreased by p0.05. There was no significant difference between the two groups in the level of other segments, different strain values. 3. 3. Compared with the young patients with hypertension, the mitral valve level, papillary muscle level, apical level and the whole level of mitral valve, mitral valve and apical value in the young obese hypertension group were significantly lower than those in the young hypertension group, and the mitral valve level and the apical value in the CS value were significantly lower than those in the control group. The level of mitral valve, the level of papillary muscle, the level of apical part and the whole level of mitral valve were decreased in the apical part and the whole level, the level of mitral valve in the apical part and the whole level was decreased (p 0.05), and the level of the apical part and the whole body was decreased (P 0.05). There was no significant difference between the two groups at other levels. Conclusion: in the young obese hypertension group, the left ventricular systolic function has been decreased in the early stage of LVEF. 4D-LVQ can be used to evaluate the global and local myocardial function of the left ventricle objectively, quantitatively and comprehensively. It can be used as a reference index for clinical evaluation of early cardiac dysfunction.
【學(xué)位授予單位】：廣西中醫(yī)藥大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2017
【分類號】：R544.1;R540.45

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