本文選題：偏頭痛 + 風火候��； 參考：《山東中醫(yī)藥大學》2015年碩士論文

【摘要】：目的:探索靜息狀態(tài)下偏頭痛風火候患者腦功能情況,分析靜息狀態(tài)下偏頭痛風火候患者功能磁共振局部一致性與生存質(zhì)量的相關性。方法:選擇2014年1月至2014年12月山東中醫(yī)藥大學在校研究生60例,其中偏頭痛風火候患者30例,健康對照組30例,年齡、性別匹配,兩組受試者均在靜息態(tài)下接受功能磁共振成像掃描,將掃描圖像預處理后進行局部一致性分析,記錄患者世界衛(wèi)生組織生存質(zhì)量測定量表簡表(WHOQOL-BREF)的生理、心理、社會、環(huán)境四個領域的得分情況,收集相關信息和數(shù)據(jù),將局部一致性改變的腦區(qū)與生存質(zhì)量進行相關性分析。結(jié)果:1.偏頭痛風火候患者生存質(zhì)量得分低于對照組。2.左側(cè)邊緣葉Re Ho值與WHOQOL-BREF生理領域得分呈顯著正相關(P0.01)。3.各活躍腦區(qū)Re Ho值與WHOQOL-BREF量表總分及心理、社會關系、環(huán)境領域得分無顯著相關性(P0.05)。左側(cè)小腦、左側(cè)額葉直回、右側(cè)上外額葉、右側(cè)背外側(cè)額上回Re Ho值與WHOQOL-BREF生理領域得分無顯著相關性(P0.05)。結(jié)論:偏頭痛風火候患者普遍生存質(zhì)量偏低,偏頭痛引起的患者生理領域生存質(zhì)量的下降可能與邊緣系統(tǒng)相關。
[Abstract]:Objective: to explore the brain function of patients with migraine wind and fire in resting state, and to analyze the correlation between local consistency of functional magnetic resonance and quality of life in patients with migraine wind and fire under resting state. Methods: from January 2014 to December 2014, 60 graduate students from Shandong University of traditional Chinese Medicine were selected, including 30 patients with migraine, 30 patients with migraine and fire, 30 healthy controls, age and sex matching. The subjects of both groups were scanned by functional magnetic resonance imaging (fMRI) under resting state. The local consistency analysis was performed after preprocessing the scanning images, and the physiological, psychological and social status of WHOQOL-BREFFS were recorded in the World Health Organization (WHO) quality of life measurement scale (WHOQOL-BREFF). The scores of the four fields of environment were collected, and the correlation analysis was made between the brain regions changed by local consistency and the quality of life (QOL). The result is 1: 1. The score of quality of life in patients with migraine wind and fire was lower than that in control group. There was a significant positive correlation between the value of re Ho in the left marginal leaf and the score of physiological field of WHOQOL-BREF. There was no significant correlation between the value of re Ho and the total score of WHOQOL-BREF scale, the scores of psychological and social relations, and the score of environmental field (P 0.05). There was no significant correlation between the value of re Ho in left cerebellum, left frontal gyrus, right superior frontal lobe and right dorsolateral superior frontal gyrus (P 0.05). Conclusion: the quality of life is low in patients with migraine wind and fire, and the decline of quality of life in physiological field may be related to the marginal system.
【學位授予單位】：山東中醫(yī)藥大學
【學位級別】：碩士
【學位授予年份】：2015
【分類號】：R445.2;R277.7

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本文編號：1838457