本文選題：高原 + 顱腦容積��； 參考：《青海大學(xué)》2014年碩士論文

【摘要】：第一部分世居高原藏漢回族健康青年人顱腔容積的測(cè)量及對(duì)比分析 目的：測(cè)量世居高原藏漢回族健康大學(xué)生的顱腔體積的大小，對(duì)比分析高原不同民族間、性別間的顱腔容積差異，同時(shí)為建立國(guó)人標(biāo)準(zhǔn)腦而提供高原健康青年人參考數(shù)據(jù)。方法：采用Siemens3.0T skyra，選取世居高原藏漢回族大學(xué)生各30人，其中男性15人，女性15人，共90名，年齡范圍18-22歲（各組間年齡差異無(wú)統(tǒng)計(jì)學(xué)意義）。所有受試者均進(jìn)行三維磁化強(qiáng)度預(yù)備梯度回波序列T1WI進(jìn)行圖像采集，并對(duì)測(cè)量結(jié)果進(jìn)行族別間的方差分析和性別間的t檢驗(yàn)。結(jié)果：藏族男、女性顱腔容積大小分別為（3117.2268±211.8688）cm3、（2712.5343±250.0785）cm3；漢族男、女性顱腔容積大小分別為（2995.7108±139.4491）cm3、（2681.9714±187.8033）cm3；回族男、女性顱腔容積大小分別為（3207.4151±267.5749）cm3、（2761.2630±168.7913）cm3。顱腔容積大小在性別上的差異具有統(tǒng)計(jì)學(xué)意義（P值均為0.000），在民族間對(duì)比分析中，漢、回男性顱腔容積大小的差異具有統(tǒng)計(jì)學(xué)意義，余各民族間顱腔容積大小的差異無(wú)統(tǒng)計(jì)學(xué)意義。結(jié)論：男性顱腔容積普遍大于女性顱腔容積，考慮與男女性別的生理因素有關(guān)；回族男性顱腔容積大于漢族男性顱腔容積，是否與民族因素有關(guān)，還有待進(jìn)一步研究；對(duì)世居高原藏漢回族青年人顱腔容積進(jìn)行準(zhǔn)確測(cè)量，不僅可以建立世居高原藏漢回族青年人標(biāo)準(zhǔn)腦容積數(shù)據(jù)，而且可為對(duì)比分析高海拔地區(qū)民族間低氧耐受引發(fā)顱內(nèi)結(jié)構(gòu)發(fā)育差異提供標(biāo)準(zhǔn)化處理的基礎(chǔ)數(shù)據(jù)。 第二部分世居高原藏漢回族健康青年人基于Argus腦形態(tài)學(xué)測(cè)量及對(duì)比分析 目的：測(cè)量世居高原藏漢回族健康大學(xué)生的橋腦、雙側(cè)豆?fàn)詈�、雙側(cè)背側(cè)丘腦容積，建立世居高原藏漢回族健康青年人標(biāo)準(zhǔn)腦參考數(shù)據(jù)，并對(duì)測(cè)量數(shù)據(jù)進(jìn)行對(duì)比分析，發(fā)現(xiàn)其差異性。方法：采用Siemens3.0T skyra，選取世居高原藏漢回族大學(xué)生各30人，共90名，其中男性45人，女性45人，年齡范圍18-22歲（各組間年齡差異無(wú)統(tǒng)計(jì)學(xué)意義）。所以志愿者均進(jìn)行三維磁化強(qiáng)度預(yù)備梯度回波序列T1WI采集圖像，原始圖像在Siemens3.0T skyra后處理站Argus容積專業(yè)測(cè)量軟件中進(jìn)行容積測(cè)量，測(cè)量結(jié)構(gòu)包括：橋腦、雙側(cè)豆?fàn)詈�、雙側(cè)背側(cè)丘腦，所以數(shù)據(jù)均以X±S表示，測(cè)量結(jié)果進(jìn)行民族間單因素方差分析、性別間兩獨(dú)立樣本t檢驗(yàn)及側(cè)別間的配對(duì)樣本t檢驗(yàn)。結(jié)果：1、在族別間比較中：藏族和回族的左側(cè)豆?fàn)詈巳莘e大于漢族，藏族的右側(cè)背側(cè)丘腦容積大于漢族；2、側(cè)別間比較中：各民族左側(cè)豆?fàn)詈思氨硞?cè)丘腦容積均大于右側(cè)；3、性別間比較中：藏漢回的橋腦容積、漢族的左、右側(cè)豆?fàn)詈思氨硞?cè)丘腦容積以及回族左、右側(cè)豆?fàn)詈巳莘e男性大于女性；差異具有統(tǒng)計(jì)學(xué)意義（p均＜0.05）。結(jié)論：1、健康藏漢回族青年人的豆?fàn)詈恕⒈硞?cè)丘腦容積左側(cè)大于右側(cè)，可能與受試者均為右利手有關(guān)。2、藏漢回族的橋腦容積、漢族的左、右側(cè)豆?fàn)詈思氨硞?cè)丘容積及回族的左、右側(cè)豆?fàn)詈巳莘e男性大于女性，可能與性別的生理原因有關(guān)，但是藏族男女的左、右側(cè)豆?fàn)詈思氨硞?cè)丘容積及回族男女的左、右側(cè)背側(cè)丘腦容積無(wú)統(tǒng)計(jì)學(xué)差異，似乎與生理原因并無(wú)關(guān)聯(lián)，其原因有待進(jìn)一步研究。3、藏族和回族的左側(cè)豆?fàn)詈巳莘e大于漢族，，藏族的右側(cè)背側(cè)丘腦容積大于漢族，其差異是否與民族因素有關(guān)，其機(jī)制尚不十分清楚，有待進(jìn)一步研究。
[Abstract]:The first part is the measurement and comparative analysis of the cranial cavity volume of Tibetan healthy youth in Tibetan Plateau.
Objective: to measure the size of the cranial cavity volume of the healthy college students of the Tibetan and Han Hui nationality in the plateau, compare and analyze the difference of the volume of the cranial cavity between the different ethnic groups in the plateau, and provide the reference data for the healthy young people of the plateau in order to establish the standard brain of the Chinese people. Method: using Siemens3.0T skyra, 30 people from the Tibetan and Han Hui students in the Tibetan Plateau were selected. There were 15 men and 15 women, with a total of 90, and the age range was 18-22 years old (there was no statistical significance for age difference between each group). All the subjects carried out the three-dimensional magnetization gradient echo sequence T1WI for image acquisition, and the results were analyzed in different ethnic groups and t test between the sexes. Results: Tibetan male and female cranial volume The size was (3117.2268 + 211.8688) cm3 and (2712.5343 + 250.0785) cm3, and the size of the cranium of the Han men was (2995.7108 + 139.4491) cm3 and (2681.9714 + 187.8033) cm3, respectively, and the size of the cranial cavity of the Hui men was (3207.4151 + 267.5749) cm3 and (2761.2630 + 168.7913) cm3. of the skull size in sex. Statistical significance (P value is 0), in the comparative analysis between ethnic groups, the difference of the size of the male cranial cavity volume is statistically significant. There is no statistical significance in the difference of the size of the cranial cavity. Conclusion: the volume of the male cranial cavity is larger than the female cranial volume, which is related to the physiological factors of male and female sex; The volume of the cranial cavity is greater than that of the Han male, and whether it is related to the national factors is still to be further studied. The accurate measurement of the volume of the cranial cavity of the young people in the Tibetan and Han Hui people in the plateau can not only establish the standard brain volume data of the young people of the Tibetan and Han Hui people in the Tibetan Plateau, but also can compare and analyze the low oxygen tolerance among the people in the high altitude areas. Basic data for standardization of brain structure development differences.
The second part is the measurement and comparative analysis of the healthy young people in Tibetan Plateau and Han Hui Plateau Based on Argus brain morphology.
Objective: to measure the bridge brain, bilateral lenticular nucleus and bilateral dorsum thalamus volume of the Tibetan and Han Hui nationality college students in the plateau, establish the standard brain reference data of the healthy young people of the Tibetan and Han Hui people in the plateau, and compare the measured data and find the difference. Methods: Siemens3.0T skyra is adopted to select the Tibetan Hui University in Tibetan and Han people in the plateau. There were 30 people with a total of 90, of which 45 men, 45 women and 18-22 years of age (there was no statistical significance for age difference between each group). So the volunteers all carried out the three-dimensional magnetization gradient echo sequence T1WI collection image, the original image was measured in the volume measurement software of the Argus volume professional measurement software after the post processing station, and measured the volume of the original image. The structure includes the bridge brain, bilateral lenticular nucleus and bilateral dorsal thalamus, so the data are X + S, and the results are analyzed by single factor analysis of variance, two independent samples t test and paired sample t test between sides. Results: 1, the left bean nucleus of the Tibetans and Hui Nationalities is larger than the Han and Tibetan. The volume of the right dorsal thalamus was greater than that of the Han nationality; 2, in the lateral comparison, the volume of the left side of the lenticular nucleus and the dorsal thalamus in all nationalities was greater than that in the right; 3, in the sex comparison, the volume of the bridge and the brain in the Han Hui, the left of the Han, the right lenticular nucleus and the volume of the dorsal thalamus, and the right lenticular nucleus of the Hui nationality were greater than that of the female; the difference was statistically significant. Study significance (P < 0.05). Conclusion: 1, the bean nucleus of the young Hui young people in healthy Tibetan and Han people, the left side of the dorsal thalamus is greater than the right. It may be related to the right hand of the right hand, and the volume of the bridge and brain in the Tibetan and Han Hui, the left of the Han, the right lenticular nucleus and the volume of the dorsum and the left of the Hui nationality, and the right lenticular volume of the right lenticular nucleus of the male is greater than that of the female. It may be related to the sex of the male. It may be related to sex. There is no statistical difference in the volume of left, right lenticular nucleus and dorsal thalamus in the left, left and right dorsal and lateral thalamus of the men and women of the Tibetan men and women, and there seems to be no correlation with the physiological reasons. The reason for it is to be further studied in.3. The left side of the Tibetan and Hui nationality is larger than the Han, and the volume of the right dorsum thalamus of the Tibetans. Whether the difference is related to ethnic factors is not clear enough to be further studied.

【學(xué)位授予單位】：青海大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2014
【分類號(hào)】：R445.2

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