本文選題：磁共振擴(kuò)散成像 + 體素內(nèi)不相關(guān)運(yùn)動(dòng)　； 參考：《臨床放射學(xué)雜志》2016年11期

【摘要】：目的探討基于體素內(nèi)不相干運(yùn)動(dòng)(IVIM)的擴(kuò)散加權(quán)成像(DWI)對(duì)乳腺腫塊病灶的診斷價(jià)值。方法前瞻性納入術(shù)前行MRI檢查且動(dòng)態(tài)對(duì)比增強(qiáng)(DCE)表現(xiàn)為乳腺腫塊的患者78例(87個(gè)病灶),分為良性組(n=29)與惡性組(n=58)。通過單、雙指數(shù)模型分別獲得表觀擴(kuò)散系數(shù)(ADC)、單純水分子擴(kuò)散系數(shù)(D)、灌注相關(guān)的擴(kuò)散系數(shù)(D*)和灌注分?jǐn)?shù)(f)參數(shù)值。采用獨(dú)立樣本t檢驗(yàn)分析組間各參數(shù)差異。繪制受試者工作特征曲線(ROC),分析各參數(shù)對(duì)乳腺腫塊病灶的診斷效能。結(jié)果惡性組ADC、D低于良性組(P0.001),惡性組D*高于良性組(P=0.04)。惡性組與良性組間f無明顯差異(P0.05)。以病理為金標(biāo)準(zhǔn),ADC、D、D*值診斷乳腺惡性腫塊病灶的曲線下面積(AUC)分別為0.88、0.92、0.62,D與ADC間差異有統(tǒng)計(jì)學(xué)意義(P=0.03)。ADC、D、D*分別以1.19×10~(-3)mm~2/s、1.05×10~(-3)mm~2/s、7.55×10~(-3)mm~2/s為診斷閾值,敏感度分別為86.2%、89.7%、89.7%,特異度分別為89.7%、93.1%、37.9%,準(zhǔn)確率分別為87.4%、89.7%、55.2%。結(jié)論 IVIM參數(shù)D對(duì)乳腺腫塊病灶的診斷效能優(yōu)于ADC,具有較高的敏感度和特異度,D*診斷效能一般,f診斷價(jià)值有限。
[Abstract]:Objective to evaluate the diagnostic value of diffusion-weighted imaging (DWI) based on voxel incoherent motion imaging (IVIMI) in breast masses. Methods 78 patients (87 lesions, divided into benign group (n = 29)) and malignant group (n = 58) who were performed MRI examination and dynamic contrast enhanced contrast enhanced MRI were divided into benign group (n = 87) and malignant group (n = 58). The parameters of apparent diffusion coefficient (ADCC), water molecular diffusion coefficient (DX), perfusion dependent diffusion coefficient (DU) and perfusion fraction (f) were obtained by single and double exponential models, respectively. T-test was used to analyze the difference of parameters between groups. The operating characteristic curve of the subjects was drawn to analyze the diagnostic effectiveness of each parameter for breast masses. Results ADCD in malignant group was lower than that in benign group (P 0.001), and D * in malignant group was higher than that in benign group (P 0.04). There was no significant difference between malignant group and benign group (P 0.05). 浠ョ梾鐞嗕負(fù)閲戞爣鍑，

本文編號(hào)：1789222