能譜CT對肺部良惡性腫塊診斷價值的初步研究.pdf.pdf 全文免費在線閱讀
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網(wǎng)友cssja335近日為您收集整理了關(guān)于能譜CT對肺部良惡性腫塊診斷價值的初步研究.pdf的文檔,希望對您的工作和學習有所幫助。以下是文檔介紹:碩士專業(yè)學位論文論文題目能譜 CT 對肺部良惡性腫塊診斷價值的初步研究研究生姓名管乃超指導教師姓名胡春洪專業(yè)名稱影像醫(yī)學與核醫(yī)學研究方向胸部影像論文提交日期 2014 年 4 月23能譜 CT 對肺部良惡性腫塊診斷價值的初步研究中文摘要I能譜 CT 對肺部良惡性腫塊診斷價值的初步研究中文摘要目的初步探討能譜CT成像技術(shù)對肺部良惡性腫塊的診斷和鑒別診斷價值。材料和方法回顧性選取經(jīng)病理確診的肺部腫塊性病變53例(腫塊長徑大于3cm),分為良性腫塊組:共16例(包括球形肺炎6例,結(jié)核瘤4例,炎性假瘤3例,機化性肺炎2例,錯構(gòu)瘤1例);惡性腫塊組:共37例(包括腺癌20例,鱗癌11例,小細胞肺癌5例,腺鱗癌1例)。應用GE寶石能譜CT(Discovery CT 750 HD)在能譜掃描模式(GSI)下行數(shù)據(jù)采集,掃描范圍從胸廓入口到膈肌水平,高壓注射器勻速注射非離子型對比劑60ml,注射流率為3.5ml/s,然后進行動脈期和靜脈期雙期掃描,通過后處理軟件GSI-viewer分別得到動脈期和靜脈期能譜曲線、40~140keV能量水平范圍內(nèi)的單能量CT值和曲線的斜率值,以及碘基圖像、水基圖像,觀察(來源:[])不同肺部腫塊病變在單能量圖像下產(chǎn)生的能譜衰減曲線形態(tài)差異,并且比較不同肺部腫塊病灶間的碘基值、水基值及病灶在各個級別單能量下的CT值及能譜曲線斜率的差別,并進行獨立樣本t檢驗。結(jié)果(1)動脈期和靜脈期40~140 keV能量水平CT值中,良性腫塊組40~80 keV區(qū)間的CT值低于惡性腫塊組,單能量越低時CT值差別越大;(2)良性腫塊組與惡性腫塊組動脈期40~70keV區(qū)間能譜曲線斜率分別為(2.38±0.31)、(2.96±0.39),差異有統(tǒng)計學意義(P<0.05);(3)動脈期和靜脈期碘基圖上,良性腫塊組的碘濃度低于惡性腫塊組,其差異有統(tǒng)計學意義(P<0.05);良性腫塊組和惡性腫塊組在動脈期和靜脈期水基值差異無明顯統(tǒng)計學意義(P>0.05);(4)肺腺癌、肺鱗癌和小細胞肺癌的動脈期能譜曲線斜率(40~70keV區(qū)間)進行比較,發(fā)現(xiàn)肺腺癌組能譜曲線的斜率平均高于肺鱗癌組和小細胞肺癌組(P<0.05);肺鱗癌組能譜曲線的斜率平均高于小細胞肺癌組,但其組間差異無明顯的統(tǒng)計學意義(P>0.0(來源:[])5)。結(jié)論肺良惡性腫塊在能譜成像上碘物質(zhì)含量具有不同的特征,能譜CT有助于中文摘要能譜 CT 對肺部良惡性腫塊診斷價值的初步研究II鑒別診斷;能譜曲線斜率對推測肺癌的某些特定病理類型具有潛在價值。關(guān)鍵詞:肺部腫塊;CT 能譜成像;單能量圖像;碘基圖像作者:管乃超指導教師:胡春洪能譜 CT 對肺部良惡性腫塊診斷價值的初步研究英文摘要IIIPreliminary Study on Diagnosis Value of Energy SpectrumCT for Benign and Malignant Pulmonary MassAbstractObjective To discuss the clinical diagnosis value of imaging in distinguishingbetween benign pulmonary masses and malignant pulmonary masses preliminarily by theenergy spectral C(來源:[])T imaging technology.Material and methods A retrospective selection of 53 cases with pulmonary masslesions (mass diameter larger than 3cm) confirmed by pathology were collected,they weredivided into benign pulmonary masses group: A total of 16 cases (including 6 cases ofspherical pneumonia, 4 cases of tuberculoma, 3 cases of inflammatory pseudotumor, 2cases anized pneumonia,1 case of hamartoma);malignant pulmonary masses group: Atotal of 37 cases ((來源:[]) including 20 cases of adenocarcinoma, 11 cases of squamous cellcarcinoma, 5 cases of small cell lung cancer, 1 case of adenosquamous carcinoma ). All thecases underwent GSI imaging of Gem energy spectrum CT(Discovery CT 750 HD),andwere by the Application of spectrum scan mode (GSI) for data mining scanning. The scanrange was from thoracic entrance to the diaphragm level.High pressure syringe infusion ofnonionic contrast agent 60ml was used,and by (來源:[])the injection rate of 3.5ml / s. Then thearterial phase and venous phase scan were taken, the CT values, slope values, iodine basedimages and water based images on 40~140 keV in arterial phase and venous phase weregot by the post processing software GSI-viewer. Then the data was analyzed pared.To observe the effects of different lung mass lesions in the single energy image obtained
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