本文選題：鼻咽癌　切入點：原發(fā)腫瘤體積　出處：《南京醫(yī)科大學學報(自然科學版)》2017年04期

【摘要】：目的:探討基于MR圖像的原發(fā)腫瘤體積測量與我國鼻咽癌2008分期中T、N和臨床分期的相關性。方法:回顧性分析2011年9月—2015年12月經病理證實的113例鼻咽癌患者的影像學及臨床資料。依據(jù)我國鼻咽癌2008分期標準判斷鼻咽癌患者的T、N和臨床分期�；跈M斷位T2加權壓脂像,逐層手動勾畫腫瘤邊界,采用面積求和法計算腫瘤體積。結果:原發(fā)腫瘤體積隨T分期進展逐漸增大(P0.01)。相鄰T分期間兩兩比較,T1/T2、T3/T4期間原發(fā)腫瘤體積差異有統(tǒng)計學意義(P0.05),T2/T3期間差異無統(tǒng)計學意義(P0.05)。全組頸部淋巴結轉移率為83.19%。N0~N3期原發(fā)腫瘤體積差異無統(tǒng)計學意義(P0.05)。臨床Ⅰ~Ⅳ期原發(fā)腫瘤體積差異有統(tǒng)計學意義(P0.01)。相鄰臨床分期間兩兩比較,Ⅰ與Ⅱ、Ⅱ與Ⅲ期間差異無統(tǒng)計學意義(P0.05),Ⅲ與Ⅳ期間差異有統(tǒng)計學意義(P0.01)。結論:鼻咽癌原發(fā)腫瘤體積與我國2008分期中T和臨床分期密切相關,可考慮將鼻咽癌原發(fā)腫瘤體積納入后續(xù)分期,以幫助判斷疾病預后。
[Abstract]:Objective: to investigate the correlation between the primary tumor volume measurement based on Mr imaging and the clinical staging of nasopharyngeal carcinoma (NPC) in 2008.Methods: the imaging and clinical data of 113 patients with nasopharyngeal carcinoma from September 2011 to December 2015 were retrospectively analyzed.According to the 2008 staging standard of nasopharyngeal carcinoma (NPC) in China, the clinical staging and Ten of nasopharyngeal carcinoma (NPC) patients were evaluated.Based on T 2 weighted fat image in transverse position, the tumor boundary was drawn manually, and the tumor volume was calculated by area summation method.Results: the volume of primary tumor increased with the development of T stage.There was significant difference in primary tumor volume between T 1 / T 2 T 2 T 3 + T 4 and T 2% T 2 / T 3. There was no significant difference in primary tumor volume during T 2 / T 3 and T 2 / T 3. There was no significant difference between T 1 / T 2 and T 2 / T 3.There was no significant difference in cervical lymph node metastasis rate between 83.19%.N0~N3 stage and primary tumor volume (P 0.05).The difference of primary tumor volume in clinical stage 鈪，

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