本文選題：微波消融　切入點(diǎn)：超聲　出處：《南方醫(yī)科大學(xué)學(xué)報》2015年03期

【摘要】：目的分析超聲引導(dǎo)經(jīng)皮微波消融脾腫瘤的可行性、安全性和有效性。方法 7例患者共8個病灶行微波消融治療,病理診斷分別為卵巢轉(zhuǎn)移癌2個,肺、胃、肝、直腸轉(zhuǎn)移癌各1個,血管瘤1個,炎性假瘤1個,腫瘤最大直徑1.3~6.2(3.1±1.9)cm。水冷微波天線在超聲引導(dǎo)下經(jīng)皮植入腫瘤內(nèi),消融中一根20 G熱敏電偶測溫針植入瘤周5 mm處實(shí)時監(jiān)測熱場溫度。微波輻射功率設(shè)置50~60 W。治療后1、3、6月以及之后每隔6個月行增強(qiáng)影像(超聲造影、CT/MRI)檢查評判療效。結(jié)果所有腫瘤均經(jīng)1次微波消融治療達(dá)到完全壞死。在中位隨訪13(4~92)月內(nèi)無腫瘤局部進(jìn)展發(fā)生。影像檢查消融區(qū)邊界清晰且隨時間延長逐漸縮小。1例卵巢癌脾轉(zhuǎn)移患者消融后11月脾臟新生另一病灶,再次行微波消融后完全壞死。轉(zhuǎn)移癌患者消融后中位生存期13.0(4.0~92.0)月。除發(fā)熱和腹痛外無治療相關(guān)嚴(yán)重并發(fā)癥發(fā)生。結(jié)論微波消融治療適合的脾臟腫瘤患者是一種安全有效的微創(chuàng)介入技術(shù)。
[Abstract]:Objective to analyze the feasibility, safety and efficacy of ultrasound guided percutaneous microwave ablation of splenic tumors.Methods 7 patients with 8 lesions were treated with microwave ablation. The pathological diagnosis was ovarian metastatic carcinoma (n = 2), lung, stomach, liver and rectum metastasis (n = 1), hemangioma (n = 1) and inflammatory pseudotumor (n = 1).The water-cooled microwave antenna was implanted into the tumor under the guidance of ultrasound. During ablation, a 20G thermocouple thermometer was implanted into the tumor to monitor the temperature of the thermal field in real time at 5 mm around the tumor.The microwave radiation power is set at 50 ~ 60 W.At 1: 3, 6 months and 6 months after treatment, CT / MRI was performed to evaluate the efficacy.Results all tumors were completely necrotic after one microwave ablation.No local tumor progression occurred during a median follow-up of 13 ~ 4 ~ 92 months.The boundary of ablation area was clear and gradually decreased with time. 1 cases of ovarian cancer patients with splenic metastasis had a new splenic neoplasm one month after ablation and complete necrosis after microwave ablation again.The median survival time of patients with metastatic carcinoma was 13.0 ~ 4.0 ~ 92.0) months after ablation.There were no serious complications associated with treatment except fever and abdominal pain.Conclusion Microwave ablation is a safe and effective minimally invasive interventional technique for splenic tumor patients.
【作者單位】： 解放軍總醫(yī)院介入超聲科;
【基金】：國家自然科學(xué)基金(81071210,81127006) 北京市自然科學(xué)基金青年基金(7144246)~~
【分類號】：R445.1;R733.2

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