本文選題：肺上葉后段占位　切入點(diǎn)：CT影像表現(xiàn)　出處：《首都醫(yī)科大學(xué)學(xué)報》2017年04期

【摘要】：目的探究惡性肺上葉后段占位性病變電子計(jì)算機(jī)斷層掃描(computed tomography,CT)良性表現(xiàn)的危險因素,為臨床診斷提供理論依據(jù)。方法回顧性研究首都醫(yī)科大學(xué)宣武醫(yī)院及首都醫(yī)科大學(xué)附屬北京友誼醫(yī)院平谷醫(yī)院胸外科2011年1月1日至2016年12月31日肺上葉后段占位性病變CT良性表現(xiàn)病人139例。計(jì)算各年份惡性肺上葉后段占位性病變CT良性影像表現(xiàn)的發(fā)生率;對比病人的各項(xiàng)臨床資料,并采用Logistic回歸分析危險因素。結(jié)果各年惡性肺上葉后段占位性病變CT良性影像表現(xiàn)的發(fā)生率分別為8.33%、11.11%、19.05%、26.92%、34.38%、40.00%;Logistic回歸顯示:年齡、吸煙、右位病變、單光子彌散計(jì)算機(jī)斷層成像術(shù)(single-photon emission computed tomography,SPECT)放射凝聚征陽性、癌胚抗原(carcino-embryonic antigen,CEA)、細(xì)胞角蛋白19片段21-1(cytokeratin protein fragment 21-1,CYFRA21-1)及神經(jīng)元特異性烯醇化酶(neuron specific enolase,NSE)異常,為惡性肺上葉后段占位性病變CT良性表現(xiàn)的危險因素,OR(95%CI)分別是1.123(1.038~1.215)、5.951(1.778~9.919)、3.547(1.104~10.397)、3.565(1.096~11.598)、18.638(4.974~29.843)、7.357(2.265~13.010)、7.639(3.107~14.697)。結(jié)論惡性肺上葉后段占位性病變CT良性影像表現(xiàn)的發(fā)生率較高,值得重視;危險因素為老齡、吸煙、右位病變、SPECT放射凝聚征陽性及肺癌相關(guān)腫瘤標(biāo)志物異常,臨床醫(yī)師需謹(jǐn)慎對待,早發(fā)現(xiàn)、早治療,以提高病人生存率。
[Abstract]:Objective to investigate the risk factors of benign manifestations of malignant upper lobe space occupying lesions in computed tomography CT (CT). Methods retrospective study on chest surgery in Pinggu Hospital, Xuanwu Hospital, Capital Medical University and Pinggu Hospital, Beijing Friendship Hospital affiliated to Capital Medical University from January 1, 2011 to December 31, 2016. The incidence of benign CT findings of malignant posterior segment of the upper lobe was calculated in 139 patients with benign CT findings. The clinical data of the patients were compared, and the risk factors were analyzed by Logistic regression analysis. Results the incidence of benign CT imaging manifestations of the malignant posterior segment of the upper lobe of the lung was 8.33 and 11.11 and 19.05 respectively. Logistic regression showed that age, smoking, right position lesions, and so on. Single-photon emission computed tomography-SPECT was positive, carcinoembryonic antigen carcinoembryonic antigen CEA, cytokeratin 19 fragment 21-1(cytokeratin protein fragment 21-1 CYFRA21-1 and neuron specific enolase specific enolase NSEs were abnormal. The risk factors for benign CT findings of malignant upper posterior lobe space occupying lesions were 1.123 / 1.0381.215A 5.9511.7789.919 / 3.5471.1047 / 1.1047 / 10.3971.5651.1.0969.59818.6384.9744 / 29.843 7.3572.26513.0107.6397.6397.6395.Conclusion the incidence of benign CT findings in the malignant posterior segment of the lung is higher than that of the controls, and the risk factors are elderly, smoking, smoking, and the risk factors are as follows: (1) the incidence of benign CT findings in the malignant posterior segment of the upper lobe of the lung is higher than that in the control group, and the risk factors are elderly, smoking, smoking, and the risk factors are as follows: (1) the incidence of benign CT findings in the posterior segment of the upper lobe of the malignant lung is higher than that in the control group, and the risk factors are elderly, smoking, and smoking. In order to improve the survival rate of patients with right lesions, the positive SPECT radiation coagulation sign and the abnormal tumor markers associated with lung cancer should be treated carefully, detected early and treated early.
【作者單位】： 首都醫(yī)科大學(xué)附屬北京友誼醫(yī)院平谷醫(yī)院胸外科;首都醫(yī)科大學(xué)宣武醫(yī)院胸外科;
【分類號】：R730.44;R734.2

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