本文選題：乳腺癌　切入點：乳房保留術　出處：《安徽醫(yī)科大學學報》2017年07期

【摘要】：目的比較左側(cè)乳腺癌保乳術后不同調(diào)強放療技術的劑量學差異。方法選取14例左側(cè)乳腺癌保乳術后患者,分別設計4野靜態(tài)調(diào)強(4F-IMRT)、混合調(diào)強(Hy-IMRT)和2個部分弧長容積旋轉(zhuǎn)調(diào)強放療(VMAT)計劃,并比較3組計劃的計劃靶區(qū)(PTV)、危及器官和正常組織劑量參數(shù)以及治療效率的差異。結果 3組計劃PTV的最小劑量、平均劑量(Dmean)、適形度指數(shù)和V_(105)相差不大,但最大劑量、均勻性指數(shù)和V_(110)差異有統(tǒng)計學意義(P0.05),其中4FIMRT的靶區(qū)劑量分布最優(yōu)。不同計劃患側(cè)肺V_5、V_(10)、V_(15)、Dmean以及心臟的V_(10)、V20差異有統(tǒng)計學意義(P0.05),HyIMRT患側(cè)肺和心臟的劑量參數(shù)優(yōu)于4F-IMRT和VMAT計劃。Hy-IMRT靶區(qū)外正常組織的V_5、V_(10)明顯優(yōu)于其它兩種計劃(P0.05)。4F-IMRT所需機器跳數(shù)(MU)最多,而VMAT的治療時間最短。結論 4F-IMRT在降低計劃靶區(qū)高劑量區(qū)體積和提高劑量均勻性等方面有明顯的優(yōu)勢;HyIMRT對左肺、右肺、心臟等危及器官保護較好,治療所需的MU也最少;VMAT可以縮短治療時間,提高患者舒適性和放療工作效率。
[Abstract]:Objective to compare the dosimetric differences of different intensity modulated radiotherapy (IMRT) techniques in patients with left breast cancer after breast conserving operation. Methods 14 patients with left breast cancer after breast conserving surgery were selected. Four field static intensity modulation (4F-IMRT), mixed intensity modulation (Hy-IMRTT) and two partial arc length volume rotational intensity modulated radiotherapy (VMATT) schemes were designed respectively. The difference of dose parameters and therapeutic efficiency between the three groups was compared. Results the minimum dose, mean dose, conformability index and maximum dose of PTV in the three groups were similar, but the maximum dose was the highest dose. There were significant differences between the homogeneity index and the VARL 110), in which the target area of 4FIMRT was the best dose distribution. There were significant differences in the dose parameters of the lung and heart of the affected side of the affected lung, V5 and VMAT. The dose parameters of the lung and the heart of the affected side were better than those of the 4F-IMRT and VMAT plans. The number of machine hops required by normal tissues outside the target area of Hy-IMRT was significantly higher than that of the other two schemes (P0.05U. 4F-IMRT). Conclusion 4F-IMRT has obvious advantages in reducing the volume of high dose area and improving the uniformity of dose in the planned target area. HyIMRT has good protection for the dangerous organs such as left lung, right lung, heart and so on. MU and VMAT can shorten the time of treatment and improve the comfort and efficiency of radiotherapy.
【作者單位】： 安徽醫(yī)科大學附屬省立醫(yī)院放療科;安徽醫(yī)科大學生命科學學院生物醫(yī)學工程系;
【基金】：安徽省高校省級自然科學研究項目(編號:KJ2010B380)
【分類號】：R730.55;R737.9

【相似文獻】

相關期刊論文 前10條

1 馬蓮花;郭麗;高滋羚;;乳腺癌保乳術的護理[J];臨床合理用藥雜志;2013年30期

2 俞宙;吳俊梅;;1例早期乳腺癌保乳術后病人并發(fā)癔癥的護理[J];家庭護士;2008年22期

3 張霞;;乳腺癌保乳術的護理[J];鄖陽醫(yī)學院學報;2008年05期

4 趙靜;;乳腺托架在乳腺癌保乳術后患者放療中的應用與護理[J];天津護理;2012年06期

5 周華;韓華;呂春靜;;乳腺癌保乳術126例護理體會[J];中國醫(yī)藥導報;2007年27期

6 周英;;乳腺癌保乳術患者的術后護理[J];中國中醫(yī)藥現(xiàn)代遠程教育;2010年05期

7 楊潤平;;乳腺癌保乳術后放療的皮膚護理干預[J];大家健康(學術版);2014年05期

8 田磊;李輝成;池琦;路雪;劉曉嵐;王鐵君;;乳腺癌保乳術后動態(tài)調(diào)強放療與常規(guī)放療的劑量學比較[J];中國輻射衛(wèi)生;2014年01期

9 楊禎;;早期乳腺癌保乳術后放療的護理體會[J];吉林醫(yī)學;2011年10期

10 謝幼華;;乳腺癌保乳術后患者護理體會[J];實用醫(yī)技雜志;2012年08期

相關會議論文 前1條

1 閆淑娟;李亞麗;孫淑杰;;乳腺癌保乳術后三維適行放射治療病人的護理[A];中華護理學會2009全國護理管理學術交流暨專題講座會議;中華護理學會2009全國護理新理論、新方法、新技術研討會論文匯編[C];2009年

相關碩士學位論文 前1條

1 胡曉娜;CBCT圖像引導下乳腺癌保乳術后放療擺位誤差分析[D];河南中醫(yī)藥大學;2016年

，

本文編號：1667242