本文選題：乳腺腫瘤　切入點：超聲自動全容積成像　出處：《遵義醫(yī)學(xué)院》2014年碩士論文　論文類型：學(xué)位論文

【摘要】：目的：探討超聲自動乳腺全容積成像（ABVS）對乳腺腫瘤的臨床診治價值，并與手持超聲（HHUS）檢查結(jié)果進行比較。 方法：將128例患者共130個乳腺腫瘤在術(shù)前接受ABVS和HHUS檢查，以穿刺活檢或手術(shù)病檢結(jié)果為金標準，計算兩者對乳腺腫瘤診斷的準確性、敏感性、特異性、陽性預(yù)測值、陰性預(yù)測值、陽性似然比、陰性似然比；以敏感性為縱坐標，以1-特異性為橫坐標，做受試者工作特征曲線（ROC曲線），，計算曲線下面積（AUC）以評估兩者的診斷價值；測量乳腺惡性腫瘤病灶最大徑并與手術(shù)病理測量結(jié)果進行對比，比較ABVS與HHUS對乳腺癌病灶的檢測情況。并用Kappa系數(shù)評估兩種檢查方法在各項相關(guān)因素（形狀、方位、邊緣、邊境、內(nèi)回聲等）中的一致性。 結(jié)果：ABVS對乳腺腫瘤診斷的準確性、敏感性、特異性、陽性預(yù)測值、陰性預(yù)測值、陽性似然比、陰性似然比分別為95.4%、94.6%、96.4%、97.2%、93.1%、26.28、0.06，HHUS為89.2%、90.5%、87.5%、90.5%、87.5%、7.24、0.11，兩者間差異存在統(tǒng)計學(xué)意義（χ2=68.532,P=0.00）；乳腺惡性腫瘤患者ABVS及HHUS測量結(jié)果與病理學(xué)結(jié)果呈顯著正相關(guān)（r=0.757,0.679,均P0.01）,ABVS測量結(jié)果與病理學(xué)測量結(jié)果之間的相關(guān)系數(shù)要高于HHUS（0.757VS0.679）；兩種檢查方法在腫瘤的形狀（K=0.601）、方向（K=0.602）、邊緣（K=0.735）、邊境（K=0.658）、內(nèi)部回聲特點（K=0.731）、后方回聲特點（K=0.676）、鈣化（K=0.620）及BI-RADS分級（K=0.700）中具有較好的一致性。結(jié)論：ABVS能為乳腺腫瘤提供更多的診斷信息，從而提高乳腺腫瘤診斷的準 確性；可以較清晰地顯示出乳腺腫瘤病灶范圍，對臨床評估乳腺惡性腫瘤病灶大小有較大的參考價值。
[Abstract]:Objective: to evaluate the clinical value of automatic breast volume imaging (ABVS) in the diagnosis and treatment of breast neoplasms, and to compare the results with HHUS. Methods: a total of 130 breast tumors were examined by ABVS and HHUS before operation. The accuracy, sensitivity, specificity and positive predictive value were calculated according to the results of biopsy or surgical examination. Negative predictive value, positive likelihood ratio, negative likelihood ratio, sensitivity as ordinate, 1- specificity as horizontal coordinate, ROC curve of subjects operating characteristic curve and area under curve were calculated to evaluate their diagnostic value. The maximum diameter of breast cancer lesions was measured and compared with the results of surgical and pathological measurements. The detection of breast cancer lesions by ABVS and HHUS was compared. The Kappa coefficient was used to evaluate the relative factors (shape, orientation, edge). Consistency in borders, internal echoes, etc. Results: the accuracy, sensitivity, specificity, positive predictive value, negative predictive value, positive likelihood ratio of the diagnosis of breast tumor were measured by the weight ABVS, the diagnostic accuracy, sensitivity, specificity, positive predictive value, positive likelihood ratio, The negative likelihood ratio was 95.44 / 94.96. 4 / 97.2and 93.1 / 26.28 / 0.06 HHUS was 89.20.92 / 90.575 / 87.5 / 87.240.11, respectively. There was a significant difference between them (蠂 2 68.532P 0.009; the results of ABVS and HHUS in breast cancer were positively correlated with pathological results rr 0.7570.79), both P0.01s and pathology were significantly correlated with the results of ABVS and pathology (P < 0.05). The number of relationship was higher than that of HHUS0.57VS0.6790.The two methods had good consistency in the shape of the tumor, the direction of the tumor was 0.602, the edge was 0.735, the border was 0.658, the internal echo was 0.731C, the posterior echo was K0.676676, the calcification was 0.620) and the BI-RADS grade was 0.700). Provide more diagnostic information, So as to improve the diagnostic accuracy of breast tumors. It can clearly show the extent of breast tumor and has great reference value for clinical evaluation of the size of breast malignant tumor.
【學(xué)位授予單位】：遵義醫(yī)學(xué)院
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2014
【分類號】：R737.9;R445.1

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