發(fā)布時(shí)間：2018-03-07 21:30

  本文選題：磁共振成像　切入點(diǎn)：磁敏感加權(quán)成像　出處：《中南大學(xué)》2014年碩士論文　論文類型：學(xué)位論文

【摘要】：研究目的本研究通過3.OT磁共振磁敏感加權(quán)成像(susceptibility Weighted imaging, SWI)及SWIM(SWI Mapping)對顱內(nèi)深靜脈系統(tǒng)的顯示能力評價(jià),探討其在創(chuàng)傷性顱腦靜脈損傷中的應(yīng)用價(jià)值。 方法收集中南大學(xué)湘雅二醫(yī)院2012-11～2014-01健康體檢、自愿者和臨床除外顱內(nèi)靜脈系統(tǒng)疾病行MRI檢查者120例。男56例,女64例,年齡13～55歲,平均35.04歲。所有受檢者經(jīng)臨床和常規(guī)MRI平掃除外顱內(nèi)占位性病變、血管畸形和靜脈竇血栓等相關(guān)疾病。由2名高年資影像科醫(yī)師對深靜脈系統(tǒng)的顯示情況進(jìn)行統(tǒng)計(jì),分析。收集中南大學(xué)湘雅二醫(yī)院2012-11～2013-12腦外傷患者60例。男37例,女23例,年齡13～72歲,平均39.05歲。所有受檢者均分別在受傷后72H內(nèi)及一月后行磁共振檢查,分別命名為急性組1、復(fù)查組2,經(jīng)臨床和常規(guī)MRI平掃除外顱內(nèi)占位性病變、血管畸形和靜脈竇血栓及以前有過外傷史的患者。由2名高年資影像科醫(yī)師判斷出血灶,達(dá)成一致意見后對各序列顯示的出血灶進(jìn)行計(jì)數(shù),對有疑問的出血灶不予進(jìn)行統(tǒng)計(jì)。結(jié)合CT、SWI的phase圖及SWIM連續(xù)層面排除小血管斷面、腦內(nèi)異物、空氣和顱底偽影后,SWI phase圖及SWIM圖上的高信號為顱內(nèi)出血灶。分別記錄MRI常規(guī)序列及SWI、SWIM圖上檢測到的出血灶數(shù)目、分布特點(diǎn)、與損傷血管的對應(yīng)關(guān)系,運(yùn)用統(tǒng)計(jì)學(xué)分析軟件SPSS13.0行統(tǒng)計(jì)分析,P0.05認(rèn)為差異有統(tǒng)計(jì)學(xué)意義。 結(jié)果本研究發(fā)現(xiàn)SWI及SWIM能夠非常清晰的顯示顱內(nèi)深靜脈的形態(tài)及解剖結(jié)構(gòu)。對顱內(nèi)一、二級深靜脈的2分以上顯示率為100%,三級深靜脈2分以上顯示率均在83.3%以上,其中,透明隔靜脈及丘腦紋狀體上靜脈等三級深靜脈的2分以上顯示率均達(dá)100%。對急性組1的共60例樣本統(tǒng)計(jì)分析,SWI及SWIM圖像共檢測出血灶數(shù)目為1105個(gè),T1WI序列檢查出血灶數(shù)目為741個(gè),T2WI序列檢測出血灶數(shù)目為772個(gè),FLAIR序列檢測出血灶數(shù)目為779個(gè)；SWI及SWIM圖像較常規(guī)MR[序列能檢測出更多的出血灶(P0.05),常規(guī)MRI序列T1WI、T2WI、FLAIR序列在顯示出血灶數(shù)目能力上沒有差別(P0.05)。對復(fù)查組2的60例樣本統(tǒng)計(jì)分析,發(fā)現(xiàn)SWI及SWIM圖像共檢測出血灶數(shù)目為1001個(gè),T1WI序列檢查出血灶數(shù)目為636個(gè),T2WI序列檢測出血灶數(shù)目為652個(gè),FLAIR序列檢測出血灶數(shù)目為723個(gè)；SWI及SWIM圖像較常規(guī)MRI序列能檢測出更多的出血灶(P0.05),常規(guī)MRI序列T1WI、T2WI、FLAIR序列在顯示出血灶數(shù)目能力上沒有差別(P0.05)。對于急性組1患者,同時(shí)還發(fā)現(xiàn)對于急性組1,SWI及SWIM還發(fā)現(xiàn)57條大腦靜脈血管有損傷征象,表現(xiàn)為血管增粗,邊緣毛糙,信號明顯不均勻等。SWI及SWIM所發(fā)現(xiàn)的1105個(gè)出血灶中,其中有277個(gè)出血灶可以找到其與損傷靜脈血管的對應(yīng)關(guān)系。 結(jié)論磁共振SWI及SWIM對顱內(nèi)深靜脈系統(tǒng)具有良好的顯示能力,能清晰顯示顱內(nèi)深靜脈的數(shù)目、形態(tài)及解剖結(jié)構(gòu)。對于創(chuàng)傷性顱腦損傷患者,SWI及SWIM圖像可以顯示腦靜脈血管形態(tài)學(xué)的改變及損傷程度,能清晰顯示顱內(nèi)出血灶的大小,形態(tài)及數(shù)目,且較常規(guī)T1WI、T2WI、FLAIR序列發(fā)現(xiàn)更多的微小腦出血灶,并能判斷出血灶與損傷靜脈的對應(yīng)關(guān)系,從而在對創(chuàng)傷性顱腦損傷病情的早期全面評估及判斷預(yù)后中起到非常重要的作用。
[Abstract]:The purpose of this study is to evaluate the display ability of intracranial deep venous system by 3.OT magnetic susceptibility weighted imaging (susceptibility Weighted imaging) and SWIM (SWI Mapping), and to explore its application value in traumatic brain injury.
Methods collected in Xiangya No.2 Hospital of Central South University from 2012-11 to 2014-01 health examination, except 120 cases of intracranial venous system diseases underwent MRI examination. The clinical volunteers and 56 cases of male, female 64 cases, age 13~55 years, average 35.04 years old. All subjects by clinical and routine MRI plain sweep out intracranial lesions, vascular malformations and venous sinus thrombosis and other related diseases. By 2 senior radiologists on the deep venous system display statistics, analysis of Xiangya No.2 Hospital of Central South University from 2012-11 to 2013-12. In patients with traumatic brain injury in 60 cases. 37 cases were male, 23 were female, age 13~72 years, average 39.05 years old. All subjects were injured after 72H and January by MRI, named acute group 1, group 2 review, by clinical and routine MRI plain sweep out intracranial lesions, vascular malformations and venous sinus thrombosis and had a history of trauma patients by 2 high. Senior radiologists judged hemorrhage after the agreement was counted on each sequence showed hemorrhage, hemorrhage not to doubt the statistics. Combining with CT, phase map and SWIM SWI continuous level of small blood vessels in the brain to exclude section, foreign body, air and skull base artifact, high signal on phase map and SWI the SWIM diagram for intracranial hemorrhage were recorded. Conventional MRI sequences and SWI, SWIM detected hemorrhage number, distribution characteristics, and the relationship between vascular injury, using statistical analysis software SPSS13.0 for statistical analysis, P0.05 believes that the difference was statistically significant.
The results of this study showed that SWI and SWIM can and anatomical structure of intracranial deep venous morphology showed very clear. A two level of intracranial deep vein, 2 points above the display rate is 100%, three deep venous rate in more than 2 grade were above 83.3%, among them, the septum pellucidum vein and thalamostriate vein body three level deep vein showed 2 points above the rate of 100%. analysis on a total of 60 cases of acute sample statistics group 1, SWI and SWIM images were detected in 1105 foci of hemorrhage, hemorrhage T1WI sequence check number was 741, the T2WI sequence in the detection of hemorrhage quantity is 772, the FLAIR sequence to detect bleeding the number of foci is 779; SWI and SWIM images than conventional MR[sequences can detect more focal hemorrhage (P0.05), conventional MRI sequence T1WI, T2WI, FLAIR showed no difference in the sequence number on the ability of hemorrhage (P0.05). Analysis of the review group 60 cases 2 sample statistics, found that SWI and SWIM map A total number of 1001 detection of hemorrhage, hemorrhage T1WI sequence check number was 636, the T2WI sequence in the detection of hemorrhage quantity is 652, the FLAIR sequence in the detection of hemorrhage number was 723; SWI and SWIM images than conventional MRI sequences can detect more focal hemorrhage (P0.05), conventional MRI sequence T1WI. T2WI, FLAIR showed no difference in sequence number on the ability of hemorrhage (P0.05). The acute group of 1 patients, also found in the acute group 1, SWI and SWIM also found 57 cerebral venous vascular injury signs showed vascular thickening, rough edge, 1105 hemorrhage signal was uneven.SWI and SWIM found, of which 277 hemorrhage can be found in the corresponding relation with injury of vein.
Conclusion magnetic resonance SWI and SWIM have good display ability of intracranial deep venous system, can clearly display the number of intracranial deep venous, morphological and anatomical structure. For patients with traumatic brain injury, SWI and SWIM images can show the morphological changes of cerebral venous and damage, intracranial hemorrhage foci can clearly show the size, shape and the number, and compared with the conventional T1WI, T2WI, FLAIR sequence showed more small cerebral hemorrhage, and can judge the relationship between hemorrhage and injury of vein, so as to judge and play a very important role in the evaluation of prognosis in the early stage of the disease of traumatic brain injury.

【學(xué)位授予單位】：中南大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2014
【分類號】：R445.2;R743

【參考文獻(xiàn)】

相關(guān)期刊論文 前1條

1 吳欣洪;黃廣龍;漆松濤;張喜安;趙丁丁;石瑾;;人腦橋靜脈及蛛網(wǎng)膜的顯微解剖研究[J];解剖學(xué)研究;2013年01期

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本文編號：1581031