本文關(guān)鍵詞： 甲狀腺腫 促甲狀腺素 彈性成像技術(shù) 剪切波速度 超聲檢查　出處：《中國全科醫(yī)學》2015年18期 　論文類型：期刊論文

【摘要】：目的應用聲輻射力脈沖成像(ARFI)技術(shù)探討彌漫性毒性甲狀腺腫(GD)患者甲狀腺組織剪切波速度(SWV)的變化。方法選取2012年12月—2013年12月在河北醫(yī)科大學第二醫(yī)院確診為GD的初發(fā)患者42例作為GD組,同時選取健康志愿者40例作為對照組。兩組均取晨起空腹血檢測甲狀腺功能及相關(guān)抗體,ARFI均由同一醫(yī)生測量甲狀腺各部位的SWV,比較GD組與對照組的SWV以及與促甲狀腺激素(TSH)間的相關(guān)性,并繪制受試者工作特征曲線(ROC曲線)。結(jié)果 GD組甲狀腺體積大于對照組(t=12.857,P0.05)。GD組患者中23例(54.8%)血流分級為Ⅲ級,16例(38.1%)為Ⅱ級,3例(7.1%)為Ⅰ級。GD組甲狀腺組織不同部位的SWV值均高于對照組(P0.05)。GD組不同部位甲狀腺組織的SWV值比較,差異無統(tǒng)計學意義(F=1.800,P=0.312)。GD組TSH與甲狀腺組織的SWV無直線相關(guān)性(r=0.254,P=0.120)。以SWV=2.1 m/s為截點時,ROC曲線下面積(AUC)最大為0.855,診斷GD的靈敏度為73.8%、特異度為90.0%、正確率為81.7%、陽性預測值為88.6%、陰性預測值為76.6%。結(jié)論 ARFI能夠客觀定量評估甲狀腺組織的硬度,對GD的診斷與鑒別診斷有一定的臨床意義。
[Abstract]:Objective to investigate the changes of shear wave velocity (SWV) in thyroid tissue of patients with diffuse toxic goiter (GDG) by means of acoustic power pulse imaging (ARFI). The first 42 cases of GD were treated as GD group. 40 healthy volunteers were selected as control group. From morning on, fasting blood samples were taken from both groups to detect thyroid function and related antibodies. SWVs in different parts of thyroid gland were measured by the same doctor. The SWV of GD group and control group were compared with that of hyperthyroidism group. The correlation between TSHs, Results the thyroid volume in GD group was larger than that in control group (12.857) P0.05. GD group (23 cases) had a blood flow grade of grade 鈪，

本文編號：1498615