本文關(guān)鍵詞： 動態(tài)對比增強磁共振成像 膠質(zhì)瘤 容積轉(zhuǎn)運常數(shù) 血管外細胞外間隙　出處：《第三軍醫(yī)大學學報》2015年23期 　論文類型：期刊論文

【摘要】：目的探討動態(tài)對比增強磁共振成像對腦膠質(zhì)瘤微血管通透性的定量評價價值。方法總共38例病理證實膠質(zhì)瘤患者使用3.0T磁共振儀器進行包括動態(tài)對比增強的磁共振檢查,獲得膠質(zhì)瘤容積轉(zhuǎn)運常數(shù)(Ktrans)和血管外細胞外間隙容積比(Ve)的最大值。不同級別膠質(zhì)瘤的Ktrans值和Ve值的差異;Ktrans值、Ve值和膠質(zhì)瘤分級之間的相關(guān)性進行統(tǒng)計學分析。結(jié)果Ⅱ級膠質(zhì)瘤Ktrans值(0.028±0.011 min-1)與Ve值(0.081±0.044)均低于Ⅲ級(0.105±0.025 min-1,0.456±0.079)和Ⅳ級(0.138±0.053 min-1,0.512±0.112),差異具有統(tǒng)計學意義(P0.01),而Ⅲ級和Ⅳ級之間差異無統(tǒng)計學意義(P0.05)。Ktrans值、Ve值和膠質(zhì)瘤分級,Ktrans值和Ve值均呈顯著正相關(guān)(P0.001)。結(jié)論動態(tài)對比增強磁共振成像可以定量評價腦膠質(zhì)瘤微血管通透性并可用于膠質(zhì)瘤術(shù)前分級。
[Abstract]:Objective to evaluate the value of dynamic contrast enhanced magnetic resonance imaging in quantitative evaluation of microvascular permeability in gliomas. Methods A total of 38 patients with pathologically proved gliomas were performed with 3.0T MRI instrument including dynamic contrast enhancement. Strong MRI. The maximum values of volume transport constant (Ktransa) and extracellular intercellular volume ratio (ECV) of gliomas were obtained. The differences of Ktrans and ve values in gliomas of different grades were obtained. Ktrans value. Results the Ktrans value of grade 鈪，

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