本文關(guān)鍵詞： 前列腺 多回波采集重度T*WI三維梯度回波 加齡性變化 磁敏感加權(quán)成像　出處：《中國(guó)醫(yī)學(xué)計(jì)算機(jī)成像雜志》2016年04期 　論文類型：期刊論文

【摘要】：目的:分析正常男性前列腺外周帶ESWAN成像的相位值、磁矩值、R2*值、T2*值隨年齡的變化規(guī)律,探討ESWAN評(píng)估外周帶加齡性變化的可行性。方法:對(duì)65名正常男性行前列腺多回波采集重度T2*加權(quán)三維梯度回波(ESWAN)成像,測(cè)量外周帶的相位值、磁矩值、R2*和T2*值,研究對(duì)象按照年齡不同分為青年、中年及老年三組,分析各組的ESWAN指標(biāo)及其年齡相關(guān)性。結(jié)果:青、中、老年組外周帶R2*值分別為15.43±2.71 Hz、16.49±3.53 Hz、20.67±5.30 Hz(F=9.402,P=0.000),T2*值依次為73.13±17.22 ms、65.56±20.15 ms、49.73±15.74 ms(F=8.433,P=0.001),磁矩值為1721.0±126.1、1489.3±247.7、1556.1±273.9(F=4.773,P=0.012);各組間相位值的差異無統(tǒng)計(jì)學(xué)意義(F=0.804,P=0.452)。相關(guān)性分析結(jié)果顯示外周帶R2*值與年齡呈正相關(guān)(r=0.477,P=0.000),而T2*值與年齡呈負(fù)相關(guān)(r=-0.510,P=0.000)。同時(shí)相位值、磁矩值與年齡的相關(guān)性分析均顯示無相關(guān)性(r=-0.095,P=0.452;r=-0.126,P=0.316)。結(jié)論:正常男性前列腺外周帶ESWAN成像與年齡具有相關(guān)性,R2*、T2*值能反映外周帶的加齡性變化。
[Abstract]:Objective: to analyze the phase value and magnetic moment value of ESWAN imaging in normal male prostatic peripheral zone. Objective: to evaluate the feasibility of ESWAN in evaluating the age of peripheral zone. Methods: 65 normal men were examined with T2 * weighted 3D gradient echo ESWAN imaging. The phase values, magnetic moment values, R2 * and T2 * values of peripheral band were measured. The subjects were divided into three groups according to their ages: youth, middle age and old age. Results: the R2 * value of peripheral zone was 15.43 鹵2.71 Hz and 16.49 鹵3.53 Hz, respectively. The values of T2 * were 73.13 鹵17.22 Ms and 65.56 鹵20.15 Ms, respectively. The magnetic moment is 1721.0 鹵126.1 鹵126.1 鹵247.7, and the magnetic moment is 1721.0 鹵126.1 鹵1489.3 鹵247.7, and the magnetic moment is 1721.0 鹵126.1 鹵1489.3 鹵247.7. 1556.1 鹵273.9FU 4.773Pu 0.012m; There was no significant difference in phase value among the groups. The correlation analysis showed that the R2 * value of the peripheral zone was positively correlated with the age of 0.477.The results of correlation analysis showed that there was a positive correlation between the R2 * value of the peripheral zone and the age. The value of T _ 2 * was negatively correlated with age, and the phase value was 0.000 ~ (-0.510) ~ 0.000 ~ 0.000 ~ 0.000 ~ 0.000 ~ 0.000 ~ 0.000 ~ 0.000 ~ 0.000 ~ 0.000, respectively. The correlation analysis of magnetic moment value and age showed that there was no correlation between r-0.095 and 0.452; Conclusion: ESWAN imaging of the peripheral zone of the prostate in normal men has a correlation with age. The value of T _ 2 * can reflect the aging change of the peripheral zone.
【作者單位】： 濰坊醫(yī)學(xué)院附屬醫(yī)院影像中心;濱州醫(yī)學(xué)院;
【基金】：國(guó)家自然科學(xué)基金項(xiàng)目(81171303,30470518) 山東省自然科學(xué)基金(ZR2009CL046,ZR2010HQ029) 山東省優(yōu)秀中青年科學(xué)家科研獎(jiǎng)勵(lì)基金(BS2012YY038) 山東省衛(wèi)生廳科技發(fā)展項(xiàng)目(2011WSB29009,2011HW067) 濱州醫(yī)學(xué)院山東省強(qiáng)化建設(shè)重點(diǎn)特色學(xué)科 山東省科技攻關(guān)項(xiàng)目(2007GG30002032,2008GG30002004) 濰坊醫(yī)學(xué)院博士科研啟動(dòng)基金(2009) “泰山學(xué)者”建設(shè)工程專項(xiàng) 山東省高校優(yōu)秀科研創(chuàng)新團(tuán)隊(duì)計(jì)劃的資助 山東省教育廳優(yōu)秀骨干教師國(guó)際合作培養(yǎng)項(xiàng)目~~
【分類號(hào)】：R445.2
【正文快照】： 根據(jù)2008年全球癌癥發(fā)病和死亡報(bào)告提供的數(shù)據(jù),在世界男性癌癥發(fā)病率中,前列腺癌高居第2位[1]。前列腺外周帶是前列腺癌最常發(fā)生的部位,75%的前列腺癌發(fā)生在外周帶。近期研究顯示,前列腺癌45歲之前發(fā)病率處于較低水平,45歲之后隨年齡增長(zhǎng),其發(fā)病率呈快速上升趨勢(shì),85歲達(dá)到最

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