【摘要】：目的了解引起小兒急性腸系膜淋巴結(jié)炎的病原學(xué)情況。方法 (1)收集44例小兒急性腸系膜淋巴結(jié)炎患兒的血清標(biāo)本,采用蛋白芯片技術(shù)同時(shí)檢測(cè)肺炎衣原體(CPn)、肺炎支原體(MP)、呼吸道合胞病毒(RSV)、腺病毒(ADV)、流感病毒(IFA)、副流感病毒(PIV)的抗體。(2)采用膠體金法對(duì)部分患兒行柯薩奇病毒CA16型、腸道病毒71型Ig M抗體的檢測(cè)。結(jié)果 (1)44例患兒檢出病原25例,總陽(yáng)性率56.8%,其中IFA檢出率為80%(20/25),MP為48%(12/25),ADV為44%(11/25)。72%(18/25)為混合感染,其中IFA+ADV感染檢出率最高,占混合感染的44%(8/18)。(2)21例患兒膠體金法檢測(cè)柯薩奇病毒CA16型與腸道病毒71型均為陰性。結(jié)論 (1)引起小兒急性腸系膜淋巴結(jié)炎病原以呼吸道感染常見(jiàn)病原體如IFA、ADV、MP為主,且大多數(shù)是混合感染,以IFA+ADV最常見(jiàn)。(2)蛋白芯片技術(shù)操作簡(jiǎn)單,且能同時(shí)檢測(cè)多種病原體,提高了效率,降低了成本。
[Abstract]:Objective to investigate the etiology of acute mesenteric lymphadenitis in children. Methods (1) the serum samples of 44 children with acute mesenteric lymphadenitis were collected. Chlamydia pneumoniae (CPn), Mycoplasma pneumoniae (MP), respiratory syncytial virus (RSV), adenoviral (ADV), was detected by protein chip technique. Antibody to influenza virus (IFA), parainfluenza virus (PIV). (2) Colloidal gold method was used to detect Coxsackie virus CA16 and enterovirus 71 Ig M antibody in some children. Results (1) 25 cases of pathogen were detected in 44 children, the total positive rate was 56.8%, of which the detection rate of IFA was 80% (20 鈮，

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