潮氣呼吸肺功能測(cè)定在嬰幼兒伴喘息的支氣管肺炎中的應(yīng)用
發(fā)布時(shí)間：2018-08-20 09:50
【摘要】：目的潮氣呼吸肺功能檢查不像傳統(tǒng)檢查需按指令配合,只需平靜自主呼吸下進(jìn)行,無(wú)創(chuàng)傷,特別適用于測(cè)定嬰幼兒肺功能,在嬰幼兒呼吸系統(tǒng)疾病應(yīng)用中有著廣泛前景,潮氣呼吸肺功能參數(shù)指標(biāo)及潮氣呼吸流速一容量環(huán)(tidal breath flow volume curve,TBFV環(huán))的變化可反映患兒肺功能損害性質(zhì)及程度,可間接評(píng)估患兒病情嚴(yán)重程度及評(píng)定藥物或治療方法的療效,本研究喘息性支氣管肺炎治療過程中潮氣呼吸肺功能的特點(diǎn),探討潮氣呼吸肺功能測(cè)定在嬰幼兒喘息性支氣管肺炎中的應(yīng)用價(jià)值,為嬰幼兒喘息性支氣管肺炎準(zhǔn)確的診斷與合理的治療提供參數(shù)指標(biāo)依據(jù)。第一部分方法選擇2013年11月-2015年12月安徽醫(yī)科大學(xué)xx醫(yī)院兒科因喘息性支氣管肺炎住院嬰幼兒共100例,健康對(duì)照組80例。分別對(duì)喘息性支氣管肺炎組入院時(shí)急性期及出院前緩解期進(jìn)行潮氣肺功能檢測(cè),觀察喘息性支氣管肺炎急性期與緩解期潮氣呼吸肺功能參數(shù)指標(biāo)、潮氣呼吸流速一容量環(huán)(TBFV環(huán))的變化,患兒在潮氣呼吸肺功能檢測(cè)前半小時(shí)進(jìn)行臨床癥狀嚴(yán)重程度評(píng)分,將喘息性支氣管肺炎分為輕度、中度、重度,比較輕、中、重度患兒之間主要潮氣呼吸肺功能參數(shù)指標(biāo)差別及臨床癥狀嚴(yán)重程度評(píng)分與入院時(shí)潮氣呼吸肺功能參數(shù)指標(biāo)的相關(guān)性。結(jié)果1、喘息性支氣管肺炎急性期觀察組患兒RR(respiratory rate,呼吸頻率)高于對(duì)照組(P0.05),TI/TE(inspiratory time/expiratory time,吸呼氣比值),TV/kg(tidal volume/kg,每千克體重潮氣量),TPTEF/TE(time to tidal peak expiratory flow/expiratory time,達(dá)峰時(shí)間比),VPEF/VE(expirator y volume at tidal peak expiratory flow/expiratory time,達(dá)峰容積比),TEF25%(the 25%tidal volume during expiratory flow,25%潮氣量時(shí)呼氣流速),TEF50%(the 50%tidal volume during expiratory flow,50%潮氣量時(shí)呼氣流速)均低于對(duì)照組(P0.05);PTEF(tidal peak expiratory flow,潮氣呼吸呼氣峰流速),TEF75%(the 75%tidal volume during expiratory flow,75%潮氣量時(shí)呼氣流速)高于對(duì)照組,但差異無(wú)顯著性(P0.05)。觀察組患兒急性期RR高于緩解期(P0.05),TI/TE,TV/kg,TPTEF/TE,VPEF/VE,TEF25%、TEF50%均低于緩解期(P0.05);PTEF,TEF75%高于緩解期,但差異無(wú)顯著性(P0.05)。觀察組患兒緩解期TI/TE,TPTEF/TE,VPEF/VE,TEF25%,TEF50%均低于對(duì)照組(P0.05),其余指標(biāo)比較差異無(wú)顯著性(P0.05)。2、喘息性支氣管肺炎潮氣呼吸流速一容量環(huán)(TBFV環(huán))急性期時(shí)表現(xiàn)為最大呼氣氣流速度降低,呼氣高峰明顯前移,呼氣時(shí)間延長(zhǎng),下降支斜率增大,甚至向容量軸凹陷,圖形呈矮胖型,經(jīng)過入院積極治療后呼氣降支的斜率較入院時(shí)降低,曲線呼氣高峰明顯后移,TFV環(huán)變寬,呼氣環(huán)降支遠(yuǎn)離容積軸。3、以TPTEF/TE和VPEF/VE作為潮氣呼吸肺功能的主要觀察指標(biāo),比較急性期喘息性支氣管肺炎患兒臨床癥狀嚴(yán)重程度評(píng)分為輕、中、重度的潮氣呼吸肺功能差別,結(jié)果發(fā)現(xiàn):急性期評(píng)分為輕度、中度及重度患者與對(duì)照組比較,中度與輕度之間比較的變化有統(tǒng)計(jì)學(xué)意義,但中、重度之間則無(wú)統(tǒng)計(jì)學(xué)的差異。喘息性支氣管肺炎臨床癥狀嚴(yán)重程度評(píng)分與入院時(shí)潮氣呼吸肺功能主要參數(shù)指標(biāo)經(jīng)Spearman等級(jí)相關(guān)分析發(fā)現(xiàn):臨床評(píng)分與TPTEF/TE,VPEF/VE呈負(fù)相關(guān),而臨床評(píng)分與VT/kg,RR,TI/TE,PTEF,TEF75%,TEF50%,TEF25%無(wú)相關(guān)性。第二部分方法選擇2013年11月-2015年12月安徽醫(yī)科大學(xué)xx醫(yī)院兒科因喘息性支氣管肺炎住院嬰幼兒共80例,健康對(duì)照組80例,根據(jù)哮喘預(yù)測(cè)指數(shù),分為喘息性支氣管肺炎組(哮喘預(yù)測(cè)指數(shù)陽(yáng)性組)、喘息性支氣管肺炎組(哮喘預(yù)測(cè)指數(shù)陰性組),分別在入院時(shí)急性期及急性期第一次潮氣呼吸肺功能檢測(cè)后立即霧化后15分鐘,出院前緩解期,出院后第14天,出院后第30天進(jìn)行潮氣呼吸肺功能檢測(cè),比較不同潮氣呼吸肺功能參數(shù)指標(biāo)的差別及兩組支氣管舒張?jiān)囼?yàn)特點(diǎn)。結(jié)果1、急性期喘息性支氣管肺炎(哮喘預(yù)測(cè)指數(shù)陽(yáng)性組)和喘息性支氣管肺炎(哮喘預(yù)測(cè)指數(shù)陰性組)肺功能指標(biāo)TPTEF/TE,VPEF/VE較對(duì)照組降低,但急性期兩組TPTEF/TE,VPEF/VE降低幅度未見明顯差異,緩解期喘息性支氣管肺炎(哮喘預(yù)測(cè)指數(shù)陽(yáng)性組)肺功能指標(biāo)TPTEF/TE,VPEF/VE和急性期相比較無(wú)統(tǒng)計(jì)學(xué)差異(P0.05),緩解期哮喘預(yù)測(cè)指數(shù)陰性組患兒的肺功能指標(biāo)TPTEF/TE,VPEF/VE較急性期上升,差異有統(tǒng)計(jì)學(xué)意義(P0.05),但仍低于正常對(duì)照組,出院后第14天哮喘預(yù)測(cè)指數(shù)陰性組的TPTEF/TE及VPEF/VE與對(duì)照組無(wú)差異,但哮喘預(yù)測(cè)指數(shù)陽(yáng)性組的TPTEF/TE及VPEF/VE仍低于對(duì)照組,出院后第30天后哮喘預(yù)測(cè)指數(shù)陽(yáng)性組的TPTEF/TE及VPEF/VE仍未恢復(fù)正常。2、喘息性支氣管肺炎(哮喘預(yù)測(cè)指數(shù)陽(yáng)性組)霧化吸藥后肺功能指標(biāo)TPTEF/TE,VPEF/VE較吸藥前明顯改善,差異有統(tǒng)計(jì)學(xué)意義(P0.05),喘息性支氣管肺炎(哮喘預(yù)測(cè)指數(shù)陰性組)霧化吸藥后肺功能指標(biāo)TPTEF/TE,VPEF/VE較吸藥前無(wú)明顯改善,差異無(wú)統(tǒng)計(jì)學(xué)意義(P0.05),喘息性支氣管肺炎(哮喘預(yù)測(cè)指數(shù)陽(yáng)性組)支氣管舒張實(shí)驗(yàn)的陽(yáng)性率為73%,喘息性支氣管肺炎(哮喘預(yù)測(cè)指數(shù)陰性組)支氣管舒張實(shí)驗(yàn)的陽(yáng)性率為21%。結(jié)論1、喘息性支氣管肺炎潮氣呼吸肺功能參數(shù)指標(biāo)治療在急性期與緩解期呈不同變化,治療后臨床癥狀雖緩解,但TPTEF/TE,VPEF/VE仍未恢復(fù)正常,小氣道仍存在阻塞。2、喘息性支氣管肺炎潮氣呼吸流速一容量環(huán)(TBFV環(huán))治療前后急性期與緩解期呈不同改變,可判斷患兒氣道阻塞部位及程度,評(píng)估治療效果。3、喘息性支氣管肺炎嚴(yán)重程度臨床評(píng)分與潮氣呼吸肺功能主要參數(shù)指標(biāo)TPTEF/TE,VPEF/VE為負(fù)相關(guān),TPTEF/TE,VPEF/VE可反映小氣道阻塞程度,評(píng)估病情的嚴(yán)重程度及變化,對(duì)疾病的臨床診療提供客觀依據(jù)。4、喘息性支氣管肺炎(哮喘預(yù)測(cè)指數(shù)陽(yáng)性組)和喘息性支氣管肺炎(哮喘預(yù)測(cè)指數(shù)陰性組)相比較,喘息性支氣管肺炎(哮喘預(yù)測(cè)指數(shù)陽(yáng)性組)肺功能恢復(fù)較喘息性支氣管肺炎(哮喘預(yù)測(cè)指數(shù)陰性組)慢,肺功能損害持續(xù)存在,需早期積極干預(yù)治療,預(yù)防發(fā)展為支氣管哮喘。5、喘息性支氣管肺炎組(哮喘預(yù)測(cè)指數(shù)陽(yáng)性組)支氣管舒張實(shí)驗(yàn)的陽(yáng)性率明顯高于喘息性支氣管肺炎組(哮喘預(yù)測(cè)指數(shù)陰性組),說明喘息性支氣管肺炎組(哮喘預(yù)測(cè)指數(shù)陽(yáng)性組)氣道可逆性程度較高,可反映兩組氣道病理生理特點(diǎn),為后續(xù)合理選擇治療方案的提供重要依據(jù)。
[Abstract]:Objective Tidal breathing pulmonary function test is not required to follow the instructions of the traditional examination, just calm and spontaneous breathing, non-invasive, especially suitable for the determination of infant pulmonary function, in infant respiratory diseases have a wide range of prospects, tidal breathing lung function parameters and tidal breath flow VO loop (tidal breath flow vo) The changes of lume curve and TBFV loop can reflect the nature and degree of pulmonary function impairment in infants. It can indirectly assess the severity of the disease and evaluate the efficacy of drugs or treatments. The purpose of this study was to investigate the characteristics of tidal breathing and pulmonary function during the treatment of asthmatic bronchopneumonia and to explore the application of tidal breathing and pulmonary function test in infants with asthmatic bronchopneumonia. The application value of asthmatic bronchopneumonia in infants and young children is to provide parameters for accurate diagnosis and reasonable treatment of asthmatic bronchopneumonia.The first part is to select 100 infants hospitalized with asthmatic bronchopneumonia in the Department of pediatrics, XX Hospital of Anhui Medical University from November 2013 to December 2015, and 80 healthy controls. In the pneumonia group, tidal pulmonary function was tested at the acute stage and remission stage before discharge, tidal respiratory function parameters, tidal breathing velocity-volume loop (TBFV loop) were observed at the acute and remission stages of asthmatic bronchopneumonia, and the severity of clinical symptoms was scored half an hour before tidal respiratory function test. Asthmatic bronchopneumonia was divided into mild, moderate, severe, mild, moderate, and severe children with major tidal breathing lung function parameters and clinical symptom severity score and admission tidal breathing lung function parameters of the correlation. results 1, asthmatic bronchopneumonia acute observation group of children RR (respiratory rate, expiratory) Inspiration frequency was higher than control group (P 0.05), TI / TE (inspiratory time / expirator y time, inspiratory / expirator y time), TV / kg (tidal volume / kg, tidal volume per kg body weight), TPTEF / TE (time to tidal peak expirator y flow / expirator y time, peak time ratio), VPEF / VE (expirator y volume at tidal peak expirator y flow / expirator y time, peak volume at peak expirator y time, peak volume at peak expirator y flow / expirator y time). Compared with the control group, TEF 25% (the 25% tidal volume during expiratory flow, 25% tidal volume during expiratory flow), TEF 50% (the 50% tidal volume during expiratory flow, 50% tidal volume during expiratory flow) were lower than the control group (P 0.05); PTEF (tidal peak expiratory flow), TEF 75% (the 75% tidal volume during expiratory flow, Respiratory flow rate at 75% tidal volume was higher than that in control group, but there was no significant difference (P 0.05). RR in acute phase was higher than that in remission phase (P 0.05), TI/TE, TV/kg, TPTEF/TE, VPEF/VE, TEF 25%, TEF 50% were lower than that in remission phase (P 0.05); PTEF and TEF 75% were higher than that in remission phase, but there was no significant difference (P 0.05). TEF 50% was lower than that of the control group (P 0.05). There was no significant difference in the other indexes (P 0.05). In the acute phase of asthmatic bronchopneumonia, the maximum expiratory velocity decreased, the peak of expiratory flow moved forward, the expiratory time prolonged, the slope of descending branch increased, even to the axis of volume depression, and the figure was short. In obese patients, after active treatment, the slope of the descending branch of the expiratory system was lower than that at admission, the peak of the curve was obviously backward, the TFV ring became wider, and the descending branch of the expiratory system was far away from the volume axis.3 Mild, moderate, and severe tidal breathing pulmonary function differences were found: acute stage score for mild, moderate and severe patients compared with the control group, moderate and mild changes in comparison with statistical significance, but no significant difference between moderate and severe. Asthmatic bronchopneumonia clinical symptom severity score and hospitalization tidal breathing Spearman rank correlation analysis showed that clinical score was negatively correlated with TPTEF / TE and VPEF / VE, while clinical score was not correlated with VT / kg, RR, TI / TE, PTEF, TEF 75%, TEF 50%, TEF 25%. Methods The second part was selected from the children hospitalized with asthmatic bronchopneumonia in XX Hospital of Anhui Medical University from November 2013 to December 2015. Eighty children and 80 healthy controls were divided into asthmatic bronchopneumonia group (positive Asthma Predictive Index group) and asthmatic bronchopneumonia group (negative Asthma Predictive Index group) according to the Asthma Predictive index. The children were admitted to the hospital immediately after the first tidal breathing pulmonary function test in the acute phase and the acute phase, and were relieved 15 minutes before discharge. Result 1. Pulmonary function of asthmatic bronchopneumonia (positive Asthma Predictive Index group) and asthmatic bronchopneumonia (negative Asthma Predictive Index group) in acute stage were compared. TPTEF/TE, VPEF/VE were lower than those in the control group, but there was no significant difference in the decrease of TPTEF/TE and VPEF/VE between the two groups in the acute phase. There was no significant difference in the lung function between the remission asthmatic bronchopneumonia (positive Asthma Predictive Index group) and the acute phase (P 0.05). TPTEF/TE and VPEF/VE were significantly higher than those in the acute phase (P 0.05), but still lower than those in the normal control group. TPTEF/TE and VPEF/VE in the negative asthma predictive index group were not different from those in the control group on the 14th day after discharge, but TPTEF/TE and VPEF/VE in the positive asthma predictive index group were still lower than those in the control group. TPTEF/TE and VPEF/VE in the positive group were not restored to normal. 2. Pulmonary function indexes TPTEF/TE and VPEF/VE in the asthmatic bronchopneumonia (positive Asthma Predictive Index group) were significantly improved after aerosol inhalation compared with those before inhalation. The difference was statistically significant (P 0.05). Pulmonary function indexes TPTEF/TE in the asthmatic bronchopneumonia (negative Asthma Predictive Index group) after aerosol inhalation. VPEF / VE showed no significant improvement compared with the control group (P 0.05). The positive rate of bronchial relaxation test in asthmatic bronchopneumonia (positive Asthma Predictive Index group) was 73%, and that in asthmatic bronchopneumonia (negative Asthma Predictive Index group) was 21%. The clinical symptoms were relieved, but TPTEF / TE, VPEF / VE did not return to normal. Small airway obstruction still existed. 2. Tidal breathing velocity - volume loop (TBFV loop) of asthmatic bronchopneumonia showed different changes before and after treatment in acute and remission stages. The severity of asthmatic bronchopneumonia was negatively correlated with TPTEF / TE, VPEF / VE. TPTEF / TE, VPEF / VE could reflect the degree of small airway obstruction, evaluate the severity and changes of the disease, and provide objective evidence for clinical diagnosis and treatment of the disease. 4, asthma. Compared with asthmatic pneumonia (positive Asthma Predictive Index group) and asthmatic bronchopneumonia (negative Asthma Predictive Index group), asthmatic bronchopneumonia (positive Asthma Predictive Index group) has slower lung function recovery than asthmatic bronchopneumonia (negative Asthma Predictive Index group). Pulmonary function damage persists and needs early active intervention. The positive rate of bronchial diastolic test in the asthmatic bronchopneumonia group (positive Asthma Predictive Index group) was significantly higher than that in the asthmatic bronchopneumonia group (negative Asthma Predictive Index group), indicating that the degree of airway reversibility in the asthmatic bronchopneumonia group (positive Asthma Predictive Index group) was higher and could reflect the airway of the two groups. Pathophysiological characteristics provide an important basis for rational selection of treatment options.
【學(xué)位授予單位】：安徽醫(yī)科大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2016
【分類號(hào)】：R725.6
本文編號(hào)：2193193
[Abstract]:Objective Tidal breathing pulmonary function test is not required to follow the instructions of the traditional examination, just calm and spontaneous breathing, non-invasive, especially suitable for the determination of infant pulmonary function, in infant respiratory diseases have a wide range of prospects, tidal breathing lung function parameters and tidal breath flow VO loop (tidal breath flow vo) The changes of lume curve and TBFV loop can reflect the nature and degree of pulmonary function impairment in infants. It can indirectly assess the severity of the disease and evaluate the efficacy of drugs or treatments. The purpose of this study was to investigate the characteristics of tidal breathing and pulmonary function during the treatment of asthmatic bronchopneumonia and to explore the application of tidal breathing and pulmonary function test in infants with asthmatic bronchopneumonia. The application value of asthmatic bronchopneumonia in infants and young children is to provide parameters for accurate diagnosis and reasonable treatment of asthmatic bronchopneumonia.The first part is to select 100 infants hospitalized with asthmatic bronchopneumonia in the Department of pediatrics, XX Hospital of Anhui Medical University from November 2013 to December 2015, and 80 healthy controls. In the pneumonia group, tidal pulmonary function was tested at the acute stage and remission stage before discharge, tidal respiratory function parameters, tidal breathing velocity-volume loop (TBFV loop) were observed at the acute and remission stages of asthmatic bronchopneumonia, and the severity of clinical symptoms was scored half an hour before tidal respiratory function test. Asthmatic bronchopneumonia was divided into mild, moderate, severe, mild, moderate, and severe children with major tidal breathing lung function parameters and clinical symptom severity score and admission tidal breathing lung function parameters of the correlation. results 1, asthmatic bronchopneumonia acute observation group of children RR (respiratory rate, expiratory) Inspiration frequency was higher than control group (P 0.05), TI / TE (inspiratory time / expirator y time, inspiratory / expirator y time), TV / kg (tidal volume / kg, tidal volume per kg body weight), TPTEF / TE (time to tidal peak expirator y flow / expirator y time, peak time ratio), VPEF / VE (expirator y volume at tidal peak expirator y flow / expirator y time, peak volume at peak expirator y time, peak volume at peak expirator y flow / expirator y time). Compared with the control group, TEF 25% (the 25% tidal volume during expiratory flow, 25% tidal volume during expiratory flow), TEF 50% (the 50% tidal volume during expiratory flow, 50% tidal volume during expiratory flow) were lower than the control group (P 0.05); PTEF (tidal peak expiratory flow), TEF 75% (the 75% tidal volume during expiratory flow, Respiratory flow rate at 75% tidal volume was higher than that in control group, but there was no significant difference (P 0.05). RR in acute phase was higher than that in remission phase (P 0.05), TI/TE, TV/kg, TPTEF/TE, VPEF/VE, TEF 25%, TEF 50% were lower than that in remission phase (P 0.05); PTEF and TEF 75% were higher than that in remission phase, but there was no significant difference (P 0.05). TEF 50% was lower than that of the control group (P 0.05). There was no significant difference in the other indexes (P 0.05). In the acute phase of asthmatic bronchopneumonia, the maximum expiratory velocity decreased, the peak of expiratory flow moved forward, the expiratory time prolonged, the slope of descending branch increased, even to the axis of volume depression, and the figure was short. In obese patients, after active treatment, the slope of the descending branch of the expiratory system was lower than that at admission, the peak of the curve was obviously backward, the TFV ring became wider, and the descending branch of the expiratory system was far away from the volume axis.3 Mild, moderate, and severe tidal breathing pulmonary function differences were found: acute stage score for mild, moderate and severe patients compared with the control group, moderate and mild changes in comparison with statistical significance, but no significant difference between moderate and severe. Asthmatic bronchopneumonia clinical symptom severity score and hospitalization tidal breathing Spearman rank correlation analysis showed that clinical score was negatively correlated with TPTEF / TE and VPEF / VE, while clinical score was not correlated with VT / kg, RR, TI / TE, PTEF, TEF 75%, TEF 50%, TEF 25%. Methods The second part was selected from the children hospitalized with asthmatic bronchopneumonia in XX Hospital of Anhui Medical University from November 2013 to December 2015. Eighty children and 80 healthy controls were divided into asthmatic bronchopneumonia group (positive Asthma Predictive Index group) and asthmatic bronchopneumonia group (negative Asthma Predictive Index group) according to the Asthma Predictive index. The children were admitted to the hospital immediately after the first tidal breathing pulmonary function test in the acute phase and the acute phase, and were relieved 15 minutes before discharge. Result 1. Pulmonary function of asthmatic bronchopneumonia (positive Asthma Predictive Index group) and asthmatic bronchopneumonia (negative Asthma Predictive Index group) in acute stage were compared. TPTEF/TE, VPEF/VE were lower than those in the control group, but there was no significant difference in the decrease of TPTEF/TE and VPEF/VE between the two groups in the acute phase. There was no significant difference in the lung function between the remission asthmatic bronchopneumonia (positive Asthma Predictive Index group) and the acute phase (P 0.05). TPTEF/TE and VPEF/VE were significantly higher than those in the acute phase (P 0.05), but still lower than those in the normal control group. TPTEF/TE and VPEF/VE in the negative asthma predictive index group were not different from those in the control group on the 14th day after discharge, but TPTEF/TE and VPEF/VE in the positive asthma predictive index group were still lower than those in the control group. TPTEF/TE and VPEF/VE in the positive group were not restored to normal. 2. Pulmonary function indexes TPTEF/TE and VPEF/VE in the asthmatic bronchopneumonia (positive Asthma Predictive Index group) were significantly improved after aerosol inhalation compared with those before inhalation. The difference was statistically significant (P 0.05). Pulmonary function indexes TPTEF/TE in the asthmatic bronchopneumonia (negative Asthma Predictive Index group) after aerosol inhalation. VPEF / VE showed no significant improvement compared with the control group (P 0.05). The positive rate of bronchial relaxation test in asthmatic bronchopneumonia (positive Asthma Predictive Index group) was 73%, and that in asthmatic bronchopneumonia (negative Asthma Predictive Index group) was 21%. The clinical symptoms were relieved, but TPTEF / TE, VPEF / VE did not return to normal. Small airway obstruction still existed. 2. Tidal breathing velocity - volume loop (TBFV loop) of asthmatic bronchopneumonia showed different changes before and after treatment in acute and remission stages. The severity of asthmatic bronchopneumonia was negatively correlated with TPTEF / TE, VPEF / VE. TPTEF / TE, VPEF / VE could reflect the degree of small airway obstruction, evaluate the severity and changes of the disease, and provide objective evidence for clinical diagnosis and treatment of the disease. 4, asthma. Compared with asthmatic pneumonia (positive Asthma Predictive Index group) and asthmatic bronchopneumonia (negative Asthma Predictive Index group), asthmatic bronchopneumonia (positive Asthma Predictive Index group) has slower lung function recovery than asthmatic bronchopneumonia (negative Asthma Predictive Index group). Pulmonary function damage persists and needs early active intervention. The positive rate of bronchial diastolic test in the asthmatic bronchopneumonia group (positive Asthma Predictive Index group) was significantly higher than that in the asthmatic bronchopneumonia group (negative Asthma Predictive Index group), indicating that the degree of airway reversibility in the asthmatic bronchopneumonia group (positive Asthma Predictive Index group) was higher and could reflect the airway of the two groups. Pathophysiological characteristics provide an important basis for rational selection of treatment options.
【學(xué)位授予單位】：安徽醫(yī)科大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2016
【分類號(hào)】：R725.6
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