發(fā)布時(shí)間：2018-08-05 16:00

【摘要】：目的分析小柴胡湯合葛根湯對(duì)小兒肺部感染高熱患者血清學(xué)指標(biāo)的影響。方法選取2016年2月-2017年2月于醫(yī)院就診的肺部感染致高熱患兒共80例,隨機(jī)分為治療組和對(duì)照組,每組各40例;兩組患兒均采用常規(guī)療法,治療組在此基礎(chǔ)上給予口服小柴胡湯合葛根湯,對(duì)比兩組患兒的治療效果和血清指標(biāo)。結(jié)果治療后,治療組的總有效率90.0%高于對(duì)照組的57.5%;治療組的中醫(yī)癥狀積分和臨床肺部感染評(píng)分(CPIS)較對(duì)照組更低;治療組患兒的血清白介素-6(IL-6)水平和腫瘤壞死因子-α(TNF-α)水平較對(duì)照組更低;治療組的退熱時(shí)間、咳嗽緩解時(shí)間和住院時(shí)間低于對(duì)照組;兩組比較差異均有統(tǒng)計(jì)學(xué)意義(P0.05)。結(jié)論小柴胡湯合葛根湯在臨床治療小兒肺部感染導(dǎo)致的高熱患兒時(shí),有效降低了其血清IL-6和TNF-α炎性細(xì)胞因子的水平,取得了很好的治療效果。
[Abstract]:Objective to analyze the effect of Xiao Chaihu Tang and Gegen Decoction on the serological indexes of children with high fever in lung infection. Methods 80 children with high fever caused by lung infection in the hospital in February -2017 in February 2016 were selected and randomly divided into treatment group and control group, each group was 40 cases. The two groups were treated with conventional therapy, and the treatment group was given the mouth on the basis of this. After the treatment, the total effective rate of the treatment group was 90% higher than that of the control group, and the TCM symptom score and the clinical pulmonary infection score (CPIS) were lower than those of the control group. The serum interleukins -6 (IL-6) level and tumor necrosis factor - alpha in the treatment group were compared with that of the control group after treatment. The level of (TNF- alpha) was lower than that of the control group; the time of fever, the time of cough remission and the time of hospitalization were lower in the treatment group than in the control group, and the difference between the two groups was statistically significant (P0.05). Conclusion the serum IL-6 and TNF- alpha inflammatory cytokines were effectively reduced by the small Chaihu Decoction and Gegen Decoction in the high fever caused by children's pulmonary infection. The level of the treatment has achieved good therapeutic effect.
【作者單位】： 海南醫(yī)學(xué)院中醫(yī)學(xué)院中醫(yī)婦兒科教研室;深圳市中醫(yī)院兒科;�？谑兄嗅t(yī)醫(yī)院兒科;海南醫(yī)學(xué)院中醫(yī)學(xué)院中西結(jié)合婦兒教研室;
【基金】：國家自然科學(xué)基金委員會(huì)資助項(xiàng)目(81503616) 中國博士后科學(xué)基金資助項(xiàng)目(2016M590840) 廣東省科技計(jì)劃基金資助項(xiàng)目(2014A020221003)
【分類號(hào)】：R725.6

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