【摘要】：目的探討酚妥拉明聯(lián)合黨參補(bǔ)肺湯(黃芪、黨參、白術(shù)等)治療嬰幼兒喘息性疾病的臨床療效及其對(duì)肺功能的影響。方法選擇2013年8月到2016年4月在我院進(jìn)行診治的嬰幼兒喘息性疾病94例,隨機(jī)分為觀察組與對(duì)照組各47例。對(duì)照組給予酚妥拉明治療,觀察組給予酚妥拉明聯(lián)合黨參補(bǔ)肺湯治療,兩組均治療7 d。結(jié)果治療后觀察組與對(duì)照組的總有效率分別為97.9%和85.1%,觀察組的總有效率明顯高于對(duì)照組(P0.05)。觀察組呼吸困難、咳嗽、發(fā)熱等癥狀的消失時(shí)間明顯快于對(duì)照組(P0.05)。觀察組面色潮紅、煩躁不安、心動(dòng)過速、惡心嘔吐等不良反應(yīng)總發(fā)生率為17.0%,對(duì)照組為19.1%,兩組對(duì)比無明顯差異(P0.05)。觀察組與對(duì)照組治療后的CD4+值明顯低于治療前(P0.05),而CD8+值明顯高于治療前(P0.05),治療后觀察組的CD4+和CD8+值與對(duì)照組對(duì)比差異也有統(tǒng)計(jì)學(xué)意義(P0.05)。觀察組與對(duì)照組治療后的FVC值分別為(83.55±15.29)%和(75.20±11.49)%,都明顯高于治療前的(68.24±15.20)%和(69.01±14.03)%(P0.05),觀察組治療后的FVC值也明顯高于對(duì)照組(P0.05)。結(jié)論酚妥拉明聯(lián)合黨參補(bǔ)肺湯治療嬰幼兒喘息性疾病具有良好的安全性,能改善臨床癥狀和免疫功能,從而促進(jìn)肺功能和治療效果的改善。
[Abstract]:Objective to investigate the clinical effect of phentoid Lemine combined with Codonopsis decoction (Astragalus, Codonopsis, Atractylodes macrocephala, etc.) in the treatment of infant wheezing diseases and its effect on lung function. Methods from August 2013 to April 2016, 94 infants with wheezing diseases were randomly divided into two groups: the observation group (n = 47) and the control group (n = 47). The control group was treated with Phenotol Lemine, the observation group was treated with phentoid Lemine combined with Codonopsis decoction for 7 days. Results the total effective rates of the observation group and the control group were 97.9% and 85.1%, respectively. The total effective rate of the observation group was significantly higher than that of the control group (P0.05). The time of disappearance of dyspnea, cough and fever in the observation group was significantly faster than that in the control group (P0.05). The total incidence of adverse reactions such as flushing, restlessness, tachycardia, nausea and vomiting was 17.0 in the observation group and 19.1in the control group. There was no significant difference between the two groups (P0.05). The CD4 value of observation group and control group after treatment was significantly lower than that before treatment (P0.05), while CD8 value was significantly higher than that before treatment (P0.05). After treatment, the CD4 and CD8 values of observation group were significantly different from those of control group (P0.05). The FVC values of the observation group and the control group were (83.55 鹵15.29)% and (75.20 鹵11.49), respectively, which were significantly higher than those before the treatment (68.24 鹵15.20)% and (69.01 鹵14.03)% (P0.05). The FVC value of the observation group was also significantly higher than that of the control group (P0.05). Conclusion Phenotol Lemine combined with Codonopsis decoction has good safety in the treatment of infant wheezing diseases and can improve clinical symptoms and immune function, thus promoting the improvement of lung function and therapeutic effect.
【作者單位】： 河北省中醫(yī)院兒科;滄州中西醫(yī)結(jié)合醫(yī)院呼吸科;
【基金】：河北省科技廳項(xiàng)目(15277712D)
【分類號(hào)】：R725.6

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