本文選題：嬰幼兒 + 喘息�。� 參考：《寧夏醫(yī)學雜志》2015年02期

【摘要】：目的分析嬰幼兒喘息與其血清總Ig E、肺功能及社會因素的關系,為臨床早期診治提供理論依據(jù)。方法收集住院患兒(28 d年齡≤3歲)共300例,其中喘息性疾病(包括毛細支氣管炎、喘息性支氣管炎、嬰幼兒哮喘)患兒150例為病例組,同期住院的下呼吸道感染而無喘息癥狀患兒150例為對照組,檢測其血清總Ig E值、行肺功能檢查,比較2組其差異性;并對入選患兒行流調(diào)問卷調(diào)查,從中分析引起嬰幼兒喘息的相關因素。結(jié)果病例組中喘息性支氣管炎、嬰幼兒哮喘患兒的血清總Ig E水平明顯高于對照組患兒,TEF 25%、TEF 50%、TPTEF/Te、VPTEF/Ve均明顯低于對照組;病例組患兒喘息與反復呼吸道感染病史、個人過敏疾病史、家族哮喘或過敏病史、既往使用抗生素、被動吸煙、家中養(yǎng)花草有關。結(jié)論嬰幼兒喘息時其血清總Ig E水平明顯升高,肺功能水平明顯下降;嬰幼兒喘息的相關因素為反復呼吸道感染病史、個人過敏疾病史、家族哮喘或過敏病史、既往使用抗生素、被動吸煙、家中養(yǎng)花草。
[Abstract]:Objective to analyze the relationship between infant wheezing and serum IgE, pulmonary function and social factors so as to provide theoretical basis for early clinical diagnosis and treatment. Methods A total of 300 hospitalized children aged less than 3 years (28 days old) were collected. 150 cases of asthmatic diseases (including bronchiolitis, wheezing bronchitis and infantile asthma) were selected as the case group. 150 children with lower respiratory tract infection and no wheezing symptoms in the same period were taken as control group. The serum IgE value and pulmonary function were measured, and the difference between the two groups was compared. The related factors of infant wheezing were analyzed. Results the serum levels of IgE in asthmatic bronchitis and asthmatic infants were significantly higher than those in the control group, and the levels of TEF25 and TEF50 were significantly lower than those in the control group, and the history of wheezing and recurrent respiratory tract infection and individual allergic diseases were significantly lower in the case group than in the control group. Family history of asthma or allergies, previous use of antibiotics, passive smoking, home gardening. Conclusion the levels of serum IgE and pulmonary function in infants with wheezing were significantly increased, and the related factors of infant wheezing were history of recurrent respiratory tract infection, history of individual allergic disease, family history of asthma or allergic disease. Previous use of antibiotics, passive smoking, home gardening.
【作者單位】： 寧夏醫(yī)科大學;寧夏醫(yī)科大學總醫(yī)院兒科;
【基金】：寧夏自然科學基金資助項目(NZ1217)
【分類號】：R725.6

【參考文獻】

相關期刊論文 前5條

1 馬秀麗;甄艷芬;;支氣管哮喘兒童血清25-(OH)D_3和總免疫球蛋白E的變化[J];中國當代兒科雜志;2011年07期

2 諸留珍,黃杰,葛蕾,李曉南;哮喘兒童PBMC培養(yǎng)上清中IL-13變化及其與嗜酸細胞計數(shù)、IgE關系探討[J];臨床兒科雜志;2005年09期

3 朱春梅;陳慧中;劉傳合;任紅雁;李碩;宋欣;趙京;;潮氣呼吸肺功能在嬰幼兒喘息性疾病診斷中的作用[J];臨床兒科雜志;2008年09期

4 張寅平;李百戰(zhàn);黃晨;楊旭;錢華;鄧啟紅;趙卓慧;李安桂;趙加寧;張昕;屈芳;胡宇;陽琴;王娟;張銘;王芳;鄭曉紅;路嬋;劉志堅;孫越霞;莫金漢;趙宜麗;劉煒;王婷婷;NORB，

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