本文選題：嬰兒 + 早產(chǎn)��； 參考：《中國感染控制雜志》2017年09期

【摘要】：目的了解早產(chǎn)兒真菌血癥患兒臨床特點。方法回顧性分析2011年1月—2015年12月某兒童醫(yī)院重癥監(jiān)護病房早產(chǎn)兒真菌血癥的臨床特點,比較早產(chǎn)兒的一般情況、實驗室相關指標及藥敏結果。結果 2011年1月—2015年12月該院收治確診的真菌血癥早產(chǎn)兒42例,其中白假絲酵母菌22例(占52.38%),近平滑假絲酵母菌13例(占30.95%),克柔假絲酵母菌3例,其他4例。按感染的主要病原菌進行分組,分為近平滑假絲酵母菌組和白假絲酵母菌組。白假絲酵母菌組母親泌尿生殖系感染率、真菌性腦膜炎的發(fā)生率均為27.27%,高于近平滑假絲酵母菌組(分別為7.69%、0.00%),白假絲酵母菌組經(jīng)外周靜脈置入中心靜脈導管(PICC)置管率低于近平滑假絲酵母菌組(22.73%vs 69.23%),近平滑假絲酵母菌組血小板計數(shù)低于白假絲酵母菌組,差異均有統(tǒng)計學意義(均P0.05)。結論早產(chǎn)兒真菌血癥感染病原菌以近平滑假絲酵母菌和白假絲酵母菌為主,母親孕期生殖系感染易導致白假絲酵母菌血癥的發(fā)生,白假絲酵母菌血癥早產(chǎn)兒更易患真菌性腦膜炎;PICC置管更易導致近平滑假絲酵母菌血癥的發(fā)生,血小板的下降更明顯。
[Abstract]:Objective to investigate the clinical characteristics of mycemia in premature infants. Methods the clinical features of mycemia of premature infants in intensive care unit of a children's hospital from January 2011 to December 2015 were analyzed retrospectively. The general situation, laboratory indexes and drug sensitivity of premature infants were compared. Results from January 2011 to December 2015, 42 cases of mycemia were diagnosed in our hospital, including 22 cases (52.38%) of Candida albicans, 13 cases (30.955%) of mycelia, 3 cases of Candida cerevisiae and 4 cases of others. According to the main pathogens of infection, they were divided into two groups: near smooth Candida cerevisiae group and Candida albicans group. Infection rate of genitourinary system in mothers of Candida albicans group, The incidence of fungal meningitis was 27.27%, which was higher than that in the near smooth Candida cerevisiae group (7.69%, respectively). The rate of PICCCimplantation in the white candida group was lower than that in the near smooth Candida cerevisiae group (22.73 vs 69.23%). The platelet count in the yeast group was lower than that in the Candida albicans group. The difference was statistically significant (P 0.05). Conclusion the pathogens of mycemia infection in premature infants are mycelia near smooth and Candida albicans. The infection of reproductive system during pregnancy may lead to the occurrence of Candida albicans. Preterm infants with mycelia were more likely to suffer from fungal meningitis and PICC catheterization was more likely to lead to the occurrence of near smooth Candida cerevisiaemia and the decrease of platelet was more obvious.
【作者單位】： 湖南省兒童醫(yī)院;
【分類號】：R722.6

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