本文選題：小兒咳嗽變異性哮喘 + 中醫(yī)藥��； 參考：《遼寧中醫(yī)藥大學(xué)》2012年碩士論文

【摘要】：研究目的：本文系統(tǒng)評(píng)價(jià)以中醫(yī)藥為主治療小兒咳嗽變異性哮喘的療效及安全性。 研究方法：通過(guò)檢索2001～2011年發(fā)表在國(guó)內(nèi)各大期刊關(guān)于中醫(yī)藥治療小兒咳嗽變異性哮喘的隨機(jī)對(duì)照臨床研究文獻(xiàn)，采用Meta分析等方法統(tǒng)計(jì)相關(guān)數(shù)據(jù)，對(duì)中醫(yī)藥治療小兒咳嗽變異性哮喘的療效以及用藥的安全性進(jìn)行系統(tǒng)的評(píng)價(jià)。 結(jié)果：通過(guò)對(duì)國(guó)內(nèi)的各大期刊的文獻(xiàn)檢索后，共檢索出相關(guān)文獻(xiàn)約302篇。其中僅有43篇滿足本研究的納入標(biāo)準(zhǔn)，應(yīng)用修改后的Jadad質(zhì)量評(píng)價(jià)表評(píng)定納入研究的文獻(xiàn)質(zhì)量普遍偏低。Meta分析結(jié)果顯示兩組在臨床總有效率、安全性以及復(fù)發(fā)率方面差異有統(tǒng)計(jì)學(xué)意義，在改善患兒肺功能方面無(wú)顯著性差異。 結(jié)論：通過(guò)對(duì)已發(fā)表的關(guān)于中醫(yī)藥治療小兒咳嗽變異性哮喘的文獻(xiàn)進(jìn)行Meta分析，初步證實(shí)中醫(yī)藥治療小兒咳嗽變異性哮喘的有效性及安全性。但因納入的文獻(xiàn)缺乏高質(zhì)量的研究，所以現(xiàn)有的評(píng)價(jià)結(jié)果不能得出肯定的結(jié)論，故對(duì)本評(píng)價(jià)的結(jié)果應(yīng)謹(jǐn)慎對(duì)待。尚需遵循“多中心，大樣本，前瞻性，，隨機(jī)對(duì)照，雙盲”科研原則，設(shè)計(jì)實(shí)施良好的臨床隨機(jī)對(duì)照試驗(yàn)，提高試驗(yàn)的質(zhì)量，為臨床研究提供指導(dǎo)及充足的證據(jù)。
[Abstract]:Research purposes: This article systematically evaluated the efficacy and safety of Chinese medicine in the treatment of infantile cough variant asthma.
Methods: a randomized controlled clinical study published on Chinese medicine for 2001~2011 years to treat children with cough variant asthma was published in 2001~2011 years. The relevant data were statistically analyzed by using the method of analysis and so on. The efficacy of Chinese medicine in treating children with cough variant asthma and the safety of drug use were systematically evaluated.
Results: About 302 articles were retrieved through the literature retrieval of the major journals in China. Only 43 of them met the inclusion criteria of this study, and the revised Jadad quality assessment table was used to assess the general low quality of the literature included in the study. The results of the.Meta analysis showed that the two groups were in the total clinical efficiency, safety and recurrence rate. The difference was statistically significant, and there was no significant difference in improving lung function in children.
Conclusion: through the Meta analysis of the published literature on the treatment of cough variant asthma in children with Chinese medicine, the effectiveness and safety of Chinese medicine in treating children with cough variant asthma are preliminarily confirmed. However, due to the lack of high quality research in the literature, the existing evaluation results can not reach a positive conclusion. The results should be treated carefully. The principle of "multi center, large sample, prospective, randomized controlled, double blind" scientific research should be followed, and a good clinical randomized controlled trial is designed and implemented to improve the quality of the test and provide guidance and sufficient evidence for clinical research.
【學(xué)位授予單位】：遼寧中醫(yī)藥大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2012
【分類號(hào)】：R272

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