補脾益肺固表方治療小兒反復呼吸道感染的臨床研究
本文選題:補脾益肺固表方 + 小兒反復呼吸道感染。 參考:《南京中醫(yī)藥大學》2017年碩士論文
【摘要】:目的:本研究通過觀察運用補脾益肺固表方治療小兒反復呼吸道感染肺脾氣虛證,并與對照組(口服匹多莫德分散片)比較,客觀的評價補脾益肺固表方治療復感兒的臨床療效。方法:本研究采用隨機平行對照的方法,將符合納入標準的60例復感兒作為受試者,分為治療組、對照組各30例。治療組予補脾益肺固表方內(nèi)服,對照組予匹多莫德分散片口服,兩組分別治療2個月。隨訪6個月,最后對統(tǒng)計數(shù)據(jù)進行分析,客觀評價兩種方案治療后的臨床療效。結(jié)果:(1)在證候療效方面,治療組總有效率為90.00%,高于對照組(76.67%),差異具有統(tǒng)計學意義(P0.05);在疾病療效方面,治療組總有效率為93.33%;高于對照組(86.67%),差異具有統(tǒng)計學意義(P0.05)。(2)在中醫(yī)證候積分評價方面:治療前2個月,兩組患兒各癥狀積分改善不明顯,對比無統(tǒng)計學差異(P0.05);在治療后隨訪的第3個月,治療組主癥積分改善較前差異有統(tǒng)計學意義,且同等時間在改善多汗、惡風寒等癥狀方面與對照組比較有統(tǒng)計學差異;治療6個月后主癥指標(面色、懶言、飲食)、次癥指標(精神、睡眠)等積分兩組間比較有統(tǒng)計學差異(P0.05),其中多汗、懶言、大便異常等癥狀積分兩組間比較,有顯著統(tǒng)計學意義(P0.01)。(3)在改善病程、病種、發(fā)病次數(shù)等方面,兩組比較差異具有統(tǒng)計學差異(P0.05);與治療前比較,兩組均可改善上呼吸道感染次數(shù),差異有統(tǒng)計學意義(P0.05)。結(jié)論:補脾益肺固表方總體療效較好,是治療小兒反復呼吸道感染的有效方法,可明顯減少呼吸道感染次數(shù),也可以改善患兒臨床癥狀,可應用于臨床,以進一步發(fā)揮中醫(yī)藥治療小兒疾病的特色與優(yōu)勢。
[Abstract]:Objective: to observe the treatment of deficiency of lung and spleen qi in children with recurrent respiratory tract infection by using the prescription of tonifying the spleen and supplementing the lung, and compare it with that of the control group (oral pidomod dispersible tablets). Objective to evaluate the clinical effect of tonifying the spleen and supplementing the lung to treat the children with complex sensation. Methods: in this study, 60 children with complex sensation were divided into treatment group (n = 30) and control group (n = 30). The treatment group was given internal administration of Bupi Yifei Gubiao recipe, the control group was treated with Pidomod dispersible tablets for 2 months respectively. Follow-up for 6 months. Finally, the statistical data were analyzed to evaluate the clinical efficacy of the two regimens. Results the total effective rate of the treatment group was 90.00g, which was higher than that of the control group 76.677.The difference was statistically significant (P 0.05), and the curative effect of the treatment group was higher than that of the control group (P < 0.05). The total effective rate of the treatment group was 93.33, which was higher than that of the control group (86.67%). The difference was statistically significant (P 0.05). In the evaluation of TCM syndromes, two months before treatment, there was no significant improvement in the symptom scores of the two groups. In the third month of follow-up, the improvement of the main symptom score in the treatment group was statistically significant compared with the control group, and there was statistical difference between the treatment group and the control group in improving hyperhidrosis and wind-cold symptoms at the same time. After 6 months of treatment, there were significant differences between the two groups in the score of the main symptoms (facial appearance, lazy speech, diet, secondary symptom index (spirit, sleep) and so on). There was a significant difference between the two groups in the score of hyperhidrosis, lazy speech, abnormal stool and other symptoms, among them, there was a significant difference between the two groups in the score of symptoms such as excessive sweating, lazy speech and abnormal stool. There was significant statistical difference between the two groups in improving the course of disease, disease species, incidence times and so on. Compared with before treatment, the two groups could improve the times of upper respiratory tract infection, and the difference was statistically significant. Conclusion: the prescription of tonifying spleen and invigorating the lung is an effective method for the treatment of recurrent respiratory tract infection in children. It can significantly reduce the number of respiratory tract infections, improve the clinical symptoms of children, and can be used in clinical practice. In order to further give play to the characteristics and advantages of traditional Chinese medicine in the treatment of pediatric diseases.
【學位授予單位】:南京中醫(yī)藥大學
【學位級別】:碩士
【學位授予年份】:2017
【分類號】:R272
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