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上海市松江區(qū)中小學(xué)生乙型肝炎血清流行病學(xué)調(diào)查

發(fā)布時(shí)間:2018-04-24 06:46

  本文選題:乙型肝炎 + 血清流行病學(xué) ; 參考:《中國公共衛(wèi)生》2017年02期


【摘要】:目的了解上海市松江區(qū)中小學(xué)生乙肝病毒(HBV)感染現(xiàn)狀,為中小學(xué)生乙型肝炎的預(yù)防控制提供參考依據(jù)。方法于2015年3—5月,采用隨機(jī)整群抽樣方法在上海市松江區(qū)抽取2 280名中小學(xué)生進(jìn)行問卷調(diào)查,并采集血樣進(jìn)行乙肝病毒表面抗原(HBsAg)、乙肝病毒表面抗體(HBsAb)、乙肝病毒核心抗體(HBcAb)、乙肝病毒e抗原(HBeAg)和乙肝病毒e抗體(HBeAb)檢測(cè)。結(jié)果上海市松江區(qū)2 280名中小學(xué)生乙肝疫苗接種率為99.87%,HBsAg、HBsAb、HBcAb、HBeAg和HBeAb陽性率分別為0.57%、26.67%、9.39%、0.22%和0.18%。不同特征中小學(xué)生比較,男生HBcAb陽性率(7.53%)低于女生(11.34%);年齡6~10歲中小學(xué)生HBsAg陽性率(34.55%)均高于11~15歲學(xué)生(26.04%)和16~20歲學(xué)生(21.86%);小學(xué)生HBsAb陽性率(31.45%)均高于初中生(23.26%)和高中生(22.01%);高中生HBcAb陽性率(11.54%)均高于小學(xué)生(9.23%)和初中生(6.34%);本地戶籍中小學(xué)生HBsAg、HBsAb和HBeAg陽性率(0.33%、19.89%和0)均低于外地戶籍學(xué)生(1.03%、39.77%和0.64%),HBcAb陽性率(10.38%)高于外地戶籍學(xué)生(7.46%),差異均有統(tǒng)計(jì)學(xué)意義(均P0.05)。結(jié)論上海市松江區(qū)中小學(xué)生乙肝接種率較高,HBsAg陽性率已降至1%。
[Abstract]:Objective to investigate the status of hepatitis B virus (HBV) infection in primary and middle school students in Songjiang District, Shanghai, and to provide reference for prevention and control of hepatitis B in primary and secondary school students. Methods A total of 2 280 primary and middle school students in Songjiang District of Shanghai were investigated by random cluster sampling from May to May 2015. Blood samples were collected for detection of HBsAg, HBsAg, HBcAb, HBeAg and HBeAb. Results the hepatitis B vaccine vaccination rates of 2 280 primary and middle school students in Songjiang District of Shanghai were 99.87% and 0.18% respectively. The positive rates of HBcAbHBeAg and HBeAb were 0.577.26.67 and 9.390.22% and 0.18%, respectively.The results showed that the hepatitis B vaccine coverage rate of 2 280 primary and middle school students in Songjiang District of Shanghai was 99.87% and 0.18% respectively. Comparison of different characteristics of Primary and Middle School students, The positive rate of HBcAb in boys (7.53) was lower than that in girls (11.34); the positive rate of HBsAg in primary and middle school students aged 6 ~ 10 years was higher than that in students aged 11 ~ 15 years (n = 34.55); it was higher in students aged 16 ~ 20 years than in students aged 16 ~ 20 years. The positive rate of HBsAb in primary school students was higher than that in junior high school students (23.26)) and the positive rate of HBcAb in high school students was 11.54) higher than that in junior high school students. The positive rates of HBcAb and HBeAg in local primary and middle school students were 0.3319.89% and 0, respectively, which were lower than those of non-resident students (1.03%, 39.77% and 0.64%), and the positive rates of HBcAb were significantly higher than those of non-resident students (all P 0.05%, P 0.05), and the positive rates of HBcAb in primary school students and junior high school students were 6.34% and 6.34%, respectively, and the difference was statistically significant (P 0.05%, P < 0.05), and the positive rate of HBcAb was significantly higher than that of non-resident students (P < 0.05%, P < 0.05). Conclusion the high HBsAg positive rate of primary and middle school students in Songjiang District of Shanghai has been reduced to 1.
【作者單位】: 復(fù)旦大學(xué)公共衛(wèi)生學(xué)院衛(wèi)生微生物學(xué)教研室;復(fù)旦大學(xué)公共衛(wèi)生學(xué)院教育部公共衛(wèi)生重點(diǎn)實(shí)驗(yàn);復(fù)旦大學(xué)衛(wèi)生部衛(wèi)生技術(shù)評(píng)估重點(diǎn)實(shí)驗(yàn)室;上海市松江區(qū)疾病預(yù)防控制中心;上海市疾病預(yù)防控制中心免疫規(guī)劃科;國民健康社會(huì)風(fēng)險(xiǎn)預(yù)警協(xié)同創(chuàng)新中心;
【基金】:國家自然科學(xué)基金面上項(xiàng)目(81373065) 上海市教育委員會(huì)科研創(chuàng)新重點(diǎn)項(xiàng)目(14ZZ015)
【分類號(hào)】:R512.62;R181.3

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