本文選題：咳嗽變異性哮喘 + 中醫(yī)藥　； 參考：《湖南中醫(yī)藥大學(xué)》2013年碩士論文

【摘要】：目的：觀察中醫(yī)分期治療咳嗽變異性哮喘(Cough variant asthma,CVA)患兒肺功能的變化,探討中藥治療CVA的作用機(jī)理。 方法：將60例CVA患兒隨機(jī)分為治療組和對(duì)照組,每組30例。治療組采用中醫(yī)分期(發(fā)作期口服溫肺化痰飲,緩解期口服補(bǔ)肺健脾飲)治療；對(duì)照組(孟魯司特鈉嚼服,發(fā)作期加服用氨茶堿),兩組總療程均為3個(gè)月。兩組分別在治療前、后行肺功能檢查。 結(jié)果：1.疾病療效：治療組總有效率96.67%,對(duì)照組總有效率93.33%,結(jié)果示兩組差異無統(tǒng)計(jì)學(xué)意義(P0.05),兩組疾病療效相當(dāng)。2.中醫(yī)證候療效：治療組總有效率96.67%,對(duì)照組總有效率86.67%,結(jié)果示兩組差異有顯著統(tǒng)計(jì)學(xué)意義(P0.01),治療組明顯優(yōu)于對(duì)照組。3.肺功能各項(xiàng)指標(biāo)治療組和對(duì)照組治療后比較兩組間差異無統(tǒng)計(jì)學(xué)意義(P0.05),其中反映大氣道功能的的指標(biāo)(FVC、 FEV1、 FEV1/FVC、PEF)兩組治療前后比較差異無統(tǒng)計(jì)學(xué)意義(P0.05),反映小氣道功能的指標(biāo)(FEF25、 FEF50、FEF75)兩組治療前后比較差異有顯著性差異(P0.01) 結(jié)論：中醫(yī)分期論治CVA與西藥組比較其疾病療效相當(dāng)；但中醫(yī)癥候療效明顯優(yōu)于西藥組；CVA主要表現(xiàn)為小氣道功能障礙,兩組均具有改善小氣道功能障礙的作用。
[Abstract]:Objective: to observe the changes of lung function in children with cough variant asthma (CVA) treated by stages with traditional Chinese medicine (TCM), and to explore the mechanism of TCM in the treatment of CVA. Methods: 60 children with CVA were randomly divided into treatment group (n = 30) and control group (n = 30). The treatment group was treated by traditional Chinese medicine stages (Wenfei Huatan decoction in attack period and Bufei Jianpi decoction in remission period), while in control group (montelukast sodium chewing, aminophylline plus aminophylline in attack period, the total course of treatment was 3 months). Lung function tests were performed before and after treatment in both groups. The result is 1: 1. The total effective rate of the treatment group was 96.67 and that of the control group was 93.33.The results showed that there was no significant difference between the two groups (P 0.05). The curative effect of the two groups was equal to that of the control group (P 0.05). The curative effect of TCM syndrome: the total effective rate of the treatment group was 96.67 and the total effective rate of the control group was 86.67.The results showed that the difference between the two groups was statistically significant (P 0.01), and the treatment group was obviously superior to the control group. 3. There was no significant difference in pulmonary function between the two groups after treatment. There was no significant difference between the two groups before and after treatment, and there was no significant difference between the two groups before and after treatment (P 0.05), which reflected the function of the small airway, including FVC, FEV1, FEV1 / FVCnPEF. FEF25, FEF50 and FEF75) there was significant difference between the two groups before and after treatment (P 0.01). Conclusion: compared with the western medicine group, the curative effect of CVA treated by stages in TCM is similar to that in the western medicine group, but the curative effect of TCM syndrome is obviously superior to that of the western medicine group. The main manifestation of TCM is small airway dysfunction, and both groups have the effect of improving the small airway dysfunction.
【學(xué)位授予單位】：湖南中醫(yī)藥大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2013
【分類號(hào)】：R272

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