發(fā)布時(shí)間：2018-04-17 16:56

  本文選題：早產(chǎn)兒 + 暫時(shí)性　； 參考：《青島大學(xué)》2012年碩士論文

【摘要】：目的研究早產(chǎn)兒暫時(shí)性甲狀腺功能減退(TH)的發(fā)生率與胎齡、出生體重、疾病的關(guān)系及其臨床表現(xiàn)。 方法選取196例早產(chǎn)兒,于生后第7天應(yīng)用電化學(xué)發(fā)光法檢測(cè)其甲狀腺素(T4)、游離甲狀腺素(FT4)、三碘甲狀腺原氨酸(T3)、游離三碘甲狀腺原氨酸(FT3)、促甲狀腺激素(TSH),并分析其與出生胎齡、出生體重關(guān)系,同時(shí)調(diào)查2周時(shí)恢復(fù)出生體重例數(shù)、規(guī)律排便例數(shù)以及新生兒黃疸嚴(yán)重程度,進(jìn)行比較。 結(jié)果1.本組研究TH陽(yáng)性率為35.7%(70/196)。 2.男、女性之間TH陽(yáng)性率無(wú)差異(p0.05)。極低出生體重組與對(duì)照組之間TH陽(yáng)性率有差異(p0.05)、小胎齡組與大胎齡組之間TH陽(yáng)性率有差異(p0.01)、新生兒缺氧缺血性腦病(HIE)組與非HIE組之間TH陽(yáng)性率有差異(p0.01)、新生兒呼吸窘迫(NRDS)組與非NRDS組之間TH陽(yáng)性率有差異(p0.01)、感染組與非感染組之間TH陽(yáng)性率有差異(p0.01)、多種疾病組與對(duì)照組之間TH陽(yáng)性率有差異(p0.01) 3.TH組的胎齡和出生體重明顯低于非TH組(兩組均p0.01)。 4.在TH組,生后14天恢復(fù)出生體重率(p0.005)、規(guī)律自主排便率(p0.01))均低于非TH組,新生兒黃疸存在數(shù)兩組無(wú)差異(P0.05)。 結(jié)論：本組調(diào)查表明早產(chǎn)兒TH的發(fā)生率為35.7%,本病的發(fā)生與胎齡、出生體重密切相關(guān),患有疾病(HIE、NRDS、感染、多種疾病)的早產(chǎn)兒其發(fā)生率更高。
[Abstract]:Objective to study the relationship between the incidence of transient hypothyroidism and gestational age, birth weight, disease and its clinical manifestations in premature infants.Methods on the 7th day after birth, 196 premature infants were detected by electrochemiluminescence (ECL) for thyroxine, free thyroxine, triiodothyronine, free triiodothyronine, free triiodothyronine, thyrotropin and TSHN, and their age at birth was analyzed.The relationship between birth weight and recovery of birth weight, regular defecation and the severity of jaundice in newborns were investigated at the same time.Result 1.The positive rate of th in this study was 35.7%.2.There was no difference in th positive rate between male and female.There were significant differences in th positive rate between very low birth weight group and control group, between small gestational age group and large gestational age group, between small gestational age group and large gestational age group, and between HIE group and non HIE group.There was significant difference in th positive rate between NRDS group and non-NRDS group, between infected group and non-infected group, between infected group and non-infected group (p0.01), and between various disease groups and control group (p0.01).The gestational age and birth weight of 3.TH group were significantly lower than that of non th group (p0.01).4.In th group, the recovery rate of birth weight and regular spontaneous defecation rate at 14 days after birth were lower than those in non-TH group. There was no difference in the number of neonatal jaundice between the two groups (P 0.05).Conclusion: the incidence of th in premature infants is 35.70.The incidence of th is closely related to gestational age, birth weight, and the incidence of HIENRDS (infection, multiple diseases) is higher in preterm infants.
【學(xué)位授予單位】：青島大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2012
【分類號(hào)】：R722.6

【參考文獻(xiàn)】

相關(guān)期刊論文 前10條

1 宋嘉;姚秀俊;楊波;李雪波;;早產(chǎn)兒甲狀腺功能的臨床研究[J];中國(guó)兒童保健雜志;2009年06期

2 李耘 ,周偉 ,張U，

本文編號(hào)：1764448