本文選題：新生兒 + 缺氧缺血性腦病　； 參考：《山東大學(xué)》2012年碩士論文

【摘要】：目的 通過對109例新生兒缺氧缺血性腦病(HIE)患兒進(jìn)行CT檢查、診斷及復(fù)查,探討新生兒缺氧缺血性腦病的CT診斷價(jià)值及其分度與預(yù)后的關(guān)系。 方法 將109例(輕度61例、中度35例、重度組13例)有窒息缺氧病史,臨床診斷為HIE的患兒行顱腦CT檢查,初次CT掃描時(shí)間為生后5小時(shí)～15天,并按影像分級標(biāo)準(zhǔn)分輕、中、重三度,其中有76例在生后1-6個月內(nèi)進(jìn)行了CT復(fù)查。 結(jié)果 ①109例HIE患兒腦CT平掃均有不同程度的腦水腫征象,CT值在8～18Hu之間。診斷為輕度HIE的66例；中度HIE的為31例,合并顱內(nèi)出血9例；重度HIE的為12例,合并顱內(nèi)出血7例。并將臨床分度與CT分度資料經(jīng)統(tǒng)計(jì)學(xué)處理進(jìn)行比較分析,經(jīng)統(tǒng)計(jì)學(xué)處理r=0.775,(P0.01),認(rèn)為CT分級與臨床分級之間有密切的相關(guān)性。②隨訪復(fù)查：最后一次CT復(fù)查所見,正常45例,單純腦溝加深13例,硬膜下積液7例,腦軟化7例,腦積水3例,腦萎縮3例,死亡2例。 結(jié)論 CT掃描檢查是診斷HIE的主要手段,能夠準(zhǔn)確的顯示病變和范圍,確定是否合并顱內(nèi)出血及出血類型,為臨床診斷和治療提供客觀的依據(jù),對HIE預(yù)后有較好的評估價(jià)值。
[Abstract]:PurposeThrough CT examination, diagnosis and reexamination of 109 neonates with hypoxic-ischemic encephalopathy (HIEs), the value of CT diagnosis and the relationship between grading and prognosis of neonates with hypoxic-ischemic encephalopathy (HIE) were discussed.MethodOne hundred and nine children (61 mild, 35 moderate, 13 severe) had a history of asphyxia and anoxia. The children diagnosed as HIE were examined by craniocerebral CT. The first CT scan time was 5 hours and 15 days after living. According to the imaging grading standard, the children were divided into mild, moderate and severe degrees.Among them, 76 cases underwent CT reexamination within 1-6 months after birth.Result1109 children with HIE had different degrees of cerebral edema on plain CT scan and the CT value was between 8~18Hu.66 cases were diagnosed as mild HIE, 31 cases with moderate HIE, 9 cases with intracranial hemorrhage, 12 cases with severe HIE and 7 cases with intracranial hemorrhage.The data of clinical grading and CT grading were compared and analyzed by statistical analysis. The results showed that there was a close correlation between CT grading and clinical grade in 45 cases.There were 13 cases of sulcus deepening, 7 cases of subdural effusion, 7 cases of encephalomalacia, 3 cases of hydrocephalus, 3 cases of cerebral atrophy and 2 cases of death.ConclusionCt scan is the main method for the diagnosis of HIE, which can accurately show the lesion and range, determine whether the intracranial hemorrhage and the type of hemorrhage, provide an objective basis for clinical diagnosis and treatment, and have a good value in evaluating the prognosis of HIE.
【學(xué)位授予單位】：山東大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2012
【分類號】：R722.1

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