本文選題：過敏性紫癜 + 腎臟損害�。� 參考：《遼寧中醫(yī)藥大學(xué)》2012年碩士論文

【摘要】：目的：通過對(duì)225例過敏性紫癜（HSP）住院患兒的回顧性調(diào)查分析，觀察過敏性紫癜患兒的舌象與腎損害發(fā)生的相關(guān)性，從而更好地辨別過敏性紫癜腎損害（HSPN）的致病因素，為HSPN的辯證治療提供更準(zhǔn)確的依據(jù)，為以后的臨床應(yīng)用及研究提供資料。 方法：采用回顧性研究方法，對(duì)2008年12月至2010年12月在遼寧中醫(yī)藥大學(xué)附屬醫(yī)院兒科住院的初發(fā)或復(fù)發(fā)的HSP患兒按照是否有腎臟損害進(jìn)行分組，選取性別、年齡、發(fā)病季節(jié)、誘因、舌象作為研究因素，所得數(shù)據(jù)應(yīng)用SPSS15.0統(tǒng)計(jì)軟件處理，單因素分析采用χ2檢驗(yàn)，多因素分析采用非條件二分類變量的Logistic回歸分析。 結(jié)果：1.患兒的一般資料：本組225例患兒中發(fā)生腎損害患兒91例，未發(fā)生腎損害患兒134例；其中男性患兒113例，女性患兒112例，男女比例約為1:1；患兒年齡分布在3~16歲，平均8.458±0.113歲；本組病例的發(fā)病季節(jié)呈四季散發(fā)，但以冬春季節(jié)略為多發(fā)，各季節(jié)所占比例分別為：春季30%，夏季18%，秋季24%，冬季28%；發(fā)病多為無明確誘因，，共140例，有明確誘因者共85例，其中上呼吸道感染最多，共75例；西醫(yī)臨床分型：腎型患兒所占比例較大，占28.9%；單純皮膚型16%；腹型25.3%；關(guān)節(jié)型10.7%；混型19.1%；中醫(yī)證型比較：風(fēng)熱傷絡(luò)型4.9%；血熱妄行型55.6%；濕熱瘀阻31.6%；陰虛火旺4.0%；氣不攝血4.0%。2.對(duì)設(shè)定的研究因素進(jìn)行單因素分析，χ2檢驗(yàn)結(jié)果顯示：兩組的性別構(gòu)成、發(fā)病誘因、季節(jié)構(gòu)成無明顯差別（P0.05）；年齡7歲（包括7歲）、發(fā)病季節(jié)冬季、舌質(zhì)紅舌、舌苔黃苔及厚膩苔與腎臟損害的發(fā)生有密切關(guān)系，有統(tǒng)計(jì)學(xué)意義（P0.05或P0.083）。3.對(duì)性別、年齡、誘因、季節(jié)、舌質(zhì)紅舌、舌苔黃苔及厚膩苔等7項(xiàng)相關(guān)因素進(jìn)行非條件二分類變量的Logistic回歸分析，結(jié)果顯示：年齡≥7歲、冬季、紅舌、厚膩苔可能是HSP患兒發(fā)生腎臟損害的重要相關(guān)因素。 結(jié)論：1.過敏性紫癜腎損害的發(fā)生可能與年齡≥7歲、冬季、紅舌、厚膩苔有相關(guān)性。2.濕邪、熱邪為過敏性紫癜腎損害的主要致病因素。3.熱邪為過敏性紫癜非腎損害的主要致病因素。
[Abstract]:Objective: to observe the correlation between tongue appearance and renal damage in 225 hospitalized children with Henoch-Schonlein purpura (HSPN), so as to better identify the pathogenic factors of HSPNs in Henoch-Schonlein purpura (Henoch-Schonlein purpura).To provide a more accurate basis for the dialectical treatment of HSPN, and to provide data for clinical application and research in the future.Methods: a retrospective study was carried out on children with HSP who were hospitalized in pediatrics department of Liaoning University of traditional Chinese Medicine from December 2008 to December 2010 according to whether they had kidney damage or not. Sex, age, onset season were selected.The data were processed by SPSS15.0 software, 蠂 2 test was used for univariate analysis and Logistic regression analysis was used for multivariate analysis.The result is 1: 1.General data of children: there were 91 cases of renal damage and 134 cases of no renal damage in this group, including 113 cases of male and 112 cases of female, the ratio of male to female was about 1: 1, the age of the children was 8.458 鹵0.113 years old (mean, 8.458 鹵0.113 years).The incidence season of this group of cases is seasonal sporadic, but slightly more frequent in winter and spring seasons. The proportion of each season is 30 in spring, 18 in summer, 24 in autumn and 28 in winter, the incidence of which is mostly without definite inducement, 140 cases, 85 cases with definite inducement, the proportion of each season is: 30 in spring, 18 in summer, 24 in autumn and 28 in winter.There were 75 cases of upper respiratory tract infection, the clinical classification of western medicine: the proportion of children with renal type was large.28. 9; skin type 16; abdominal type 25. 3; joint type 10. 7; mixed type 19. 1; TCM syndromes comparison: wind and heat injury collateral type 4. 9; blood heat type 55.6; damp-heat stasis 31. 6; Yin deficiency fire flourishing 4. 0; qi not absorbing blood 4. 0. 2.Univariate analysis showed that there were no significant differences in sex composition, onset inducement and seasonal composition between the two groups, age 7 years (including 7 years old, onset season and winter), tongue red tongue, and the age of 7 years old (including 7 years old, onset season and winter) were not significantly different between the two groups.Yellow tongue coating and thick greasy coating were closely related to the occurrence of renal damage, with statistical significance (P0.05) or P0.083 ~ (3). 3.The factors related to sex, age, inducement, season, tongue red tongue, yellow tongue coating and thick and greasy tongue coating were analyzed by Logistic regression analysis. The results showed that age 鈮

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