本文選題：手足口病　切入點(diǎn)：危重癥　出處：《南昌大學(xué)》2012年碩士論文

【摘要】：目的：探討無(wú)創(chuàng)正壓通氣輔助治療重癥手足口病的療效。 方法：對(duì)我院2011年1月至2011年12月就診的65例重癥手足口病患者（2期、3期），觀察組30例，對(duì)照組35例。對(duì)照組按常規(guī)方法治療（米力農(nóng)、甲潑尼龍、丙種球蛋白等），觀察組在常規(guī)治療的基礎(chǔ)上加經(jīng)鼻持續(xù)氣道正壓。觀察兩組血?dú)�、心率、血壓、血糖、白�?xì)胞、住院時(shí)間、病情進(jìn)展、有創(chuàng)機(jī)械通氣等情況。 結(jié)果：觀察組和對(duì)照組的PaO2分別為（83.6±19.4）mmHg和（71.7±17.5）mmHg兩者有顯著性差異(P 0.05)；觀察組和對(duì)照組的PaCO2分別為（33.4±11.5）mmHg和（36.3±12.8）mmHg兩者有顯著性差異(P 0.05);觀察組和對(duì)照組SaO2分別為（94.5±15.4）%和（89.3±17.6）%兩者有顯著性差異(P 0.05)；觀察組和對(duì)照組的心率分別為（112.3±12.2）次/分和（125.5±13.4）次/分，兩者有顯著性差異(P 0.05)；血壓觀察組（90.3±10.7）/（52.5±6.8）mmHg，和對(duì)照組（108.2±9.9）/（64.3±5.5）兩者有顯著性差異(P 0.05)；觀察組和對(duì)照組的白細(xì)胞計(jì)數(shù)分別為（9.3±2.3）x109.L-1和（9.2±3.6）x109.L-1，兩者無(wú)顯著性差異（P0.05）；觀察組和對(duì)照組的血糖分別為（5.3±1.7）c/mmpl.L1和（5.5±1.2）c/mmpl.L1兩者無(wú)顯著性差異（P0.05）；觀察組和對(duì)照組住院時(shí)間（9.2±2.1）天和（13.2±4.6）天；兩者有顯著性差異(P 0.05);觀察組和對(duì)照組的病情進(jìn)展:2期觀察組有0例進(jìn)入3期，對(duì)照組有7例進(jìn)入3期，兩者有顯著性差異(P 0.05)；觀察組和對(duì)照組的病情進(jìn)展:3期觀察組0例進(jìn)入4期，對(duì)照組有8例進(jìn)入4期，兩者有顯著性差異(P 0.05)；觀察組和對(duì)照組有創(chuàng)機(jī)械通氣使用率分別為0%和20%，兩者有顯著性差異(P 0.05)。 結(jié)論：常規(guī)治療的基礎(chǔ)上加用經(jīng)鼻持續(xù)氣道正壓通氣治療重癥手足口病,在改善低氧血癥及循環(huán)功能，，縮短住院時(shí)間，減少有創(chuàng)機(jī)械通氣，阻止重癥病例向危重癥發(fā)展有重要作用。
[Abstract]:Objective: To explore the therapeutic effect of noninvasive positive pressure ventilation in the treatment of severe hand foot and mouth disease.
Methods: 65 patients with severe hand foot in our hospital from January 2011 to December 2011 were mouth disease (2, 3), 30 cases in the observation group, 35 cases in the control group. The control group was treated by conventional methods (milrinone, methylprednisolone, gamma globulin and so on), the observation group based on routine treatment combined with nasal continuous positive airway pressure. Observe two groups of blood gas, heart rate, blood pressure, blood glucose, white blood cells, hospitalization time, disease progression, invasive mechanical ventilation.
緇撴灉錛氳瀵熺粍鍜屽鐓х粍鐨凱aO2鍒嗗埆涓

本文編號(hào)：1709346