本文選題：舒芬太尼　切入點(diǎn)：芬太尼　出處：《中國內(nèi)鏡雜志》2017年05期 　論文類型：期刊論文

【摘要】：目的觀察舒芬太尼在兒童全麻腸鏡檢查中的臨床效果和安全性。方法擇期全麻下行腸鏡檢查患兒80例,年齡5~10歲,體重18~35 kg,隨機(jī)分為舒芬太尼組(S組)和芬太尼組(F組),每組40例。S組靜注舒芬太尼0.2μg/kg,F組靜注芬太尼2.0μg/kg,隨后兩組均靜注丙泊酚2.50 mg/kg,置入雙腔喉罩,丙泊酚6.00~8.00 mg/(kg·h)泵注復(fù)合七氟醚2%~3%維持麻醉。記錄麻醉誘導(dǎo)前(T_0)、放置喉罩時(shí)(T_1)、腸鏡至回盲瓣時(shí)(T_2)及手術(shù)結(jié)束時(shí)(T_3)等時(shí)點(diǎn)的心率(HR)、平均動脈壓(MAP)、脈搏氧飽和度(Sp O_2)及呼吸頻率(RR),同時(shí)記錄蘇醒時(shí)間、注射部位疼痛、術(shù)中體動、術(shù)中有無返流、術(shù)后舌后墜、惡心嘔吐、咽喉部疼痛及躁動等情況。結(jié)果 F組在T1和T2時(shí)HR、MAP高于麻醉誘導(dǎo)前(P0.05),而S組HR、MAP差異無統(tǒng)計(jì)學(xué)意義(P0.05)。T_1時(shí)兩組RR均較誘導(dǎo)前明顯降低(P0.05),組間比較差異無統(tǒng)計(jì)學(xué)意義(P0.05)。T_1、T_2時(shí)S組HR和MAP明顯低于F組(P0.05)。S組注射疼、誘導(dǎo)及蘇醒時(shí)間、術(shù)后躁動發(fā)生率均較F組低(P0.05)。結(jié)論舒芬太尼用于靜吸復(fù)合全麻雙腔喉罩通氣下行小兒腸鏡檢查安全有效,麻醉效果滿意,術(shù)中呼吸循環(huán)更穩(wěn)定,術(shù)后蘇醒質(zhì)量高。
[Abstract]:Objective to observe the clinical effect and safety of sufentanil in children with general anesthesia. The rats were randomly divided into sufentanil group (n = 40) and fentanyl group (n = 40) and fentanyl group (n = 40). Sufentanil 0.2 渭 g / kg / kg F group was given fentanyl 2.0 渭 g / kg, and then propofol 2.50 mg / kg / kg was injected intravenously. Propofol 6. 00 mg/(kg 路h) pump combined with sevoflurane 2% maintenance anaesthesia. Record the heart rate HRR, mean arterial pressure (MAPP), pulse oxygen saturation (SPO 2), pulse oxygen saturation (SPO 2), pulse oxygen saturation (SPO 2) at the time points such as T 0, T 1, T 2) when the laryngeal mask is placed, and T 2 at the end of the operation and at the end of the operation. At the same time, the time of awakening was recorded. Injection site pain, intraoperative body movement, intraoperative reflux, postoperative tongue drop, nausea and vomiting, Results HRMAP at T1 and T2 in group F was higher than that before anesthesia induction, but there was no significant difference in HRMAP between group S and group S (P 0.05). The RR of group T 1 was significantly lower than that of group B (P 0.05), but there was no significant difference between the two groups. HR and MAP in group S were significantly lower than those in group F (P 0.05). The incidence of postoperative restlessness in group F was lower than that in group F. ConclusionSufentanil is safe and effective in the examination of pediatric colonoscopy under double lumen laryngeal mask ventilation with intravenous inhalation and general anesthesia, and the effect of anesthesia is satisfactory, and the respiration and circulation are more stable during operation. The quality of postoperative recovery is high.
【作者單位】： 南京醫(yī)科大學(xué)附屬兒童醫(yī)院麻醉科;
【分類號】：R726.1

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