本文選題：呼出氣一氧化氮　切入點：學(xué)齡前期　出處：《中國實用兒科雜志》2017年03期 　論文類型：期刊論文

【摘要】：目的對比3~5歲兒童清醒狀態(tài)下,使用面罩潮氣呼吸法和口腔潮氣呼吸法所測出的呼出氣一氧化氮(Fe NO),探討3~5歲兒童Fe NO的檢測方法。方法將廣州市婦女兒童醫(yī)療中心2016年1月至2016年8月符合入選標(biāo)準的55例兒童作為研究對象,分別使用面罩潮氣呼吸法和口腔潮氣呼吸法進行Fe NO檢測,并對結(jié)果進行對比分析。結(jié)果無咳喘癥狀兒童無論有無鼻炎,使用口腔潮氣呼吸法測出的Fe NO均明顯低于面罩潮氣呼吸法所測結(jié)果:分別使用口腔潮氣呼吸法和面罩潮氣呼吸法測Fe NO,有鼻炎患兒為(7.8±10.6)×10~(-9)和(15.8±9.9)×10~(-9);無鼻炎患兒為(5.0±4.5)×10~(-9)和(14.0±10.0)×10~(-9),均P0.05;有咳喘癥狀兒童,無論有無鼻炎,使用口腔潮氣呼吸法測出Fe NO明顯低于面罩潮氣呼吸法所測結(jié)果;分別使用口腔潮氣呼吸法和面罩潮氣呼吸法測Fe NO,有鼻炎患兒為6.1×10~(-9)[(2.1~16.3)×10~(-9)]和11.6×10~(-9)[(4.1~26.5)×10~(-9)],無鼻炎患兒為4.6×10~(-9)[(1.9~9.9)×10~(-9)]和11.5×10~(-9)[(6.5~25.8)×10~(-9)],均P0.05。結(jié)論 3~5歲兒童使用潮氣呼吸法進行Fe NO檢測時,口腔潮氣呼吸法比面罩潮氣呼吸法更能正確反應(yīng)氣道炎癥真實情況。~
[Abstract]:Objective to compare the awake state of children aged 3 to 5 years old, Using mask tidal breathing method and oral tidal breathing method to detect the exhalation nitric oxide (no) and nitric oxide (FNO) in children aged 3 to 5 years, the method of detecting Fe no in children aged 3 ~ 5 years was studied. Methods the Guangzhou Medical Center for Women and Children from January 2016 to August 2016 was enrolled in the study. A total of 55 children were selected as subjects. Fe no was detected by mask tidal breathing method and oral tidal breathing method, and the results were compared and analyzed. Results No cough and asthma symptoms were found in children with or without rhinitis. Fe no measured by oral tidal breathing method was significantly lower than that measured by mask tidal breathing method: in children with rhinitis, it was 7.8 鹵10.6 脳 10 ~ (-9) 脳 10 ~ (9) and 15.8 鹵9.9) 脳 10 ~ (10) ~ (-9), and that in children without rhinitis was 5.0 鹵4.5 脳 10 ~ (10 ~ (-9)) and 10 ~ (10 ~ (-9)) in children without rhinitis, respectively, and in children without rhinitis it was 5.0 鹵4.5 脳 10 ~ (-9)), and that in children without rhinitis was 5.0 鹵4.5 脳 10 ~ (-9)). 14. 0 鹵10. 0) 脳 10 ~ (-9) (P < 0. 05). With or without rhinitis, the measurement of FeNO by oral tidal breathing method was significantly lower than that by mask tidal breathing method. The determination of Fe _ (no) in children with rhinitis by oral tidal breathing method and mask tidal breathing method was 6.1 脳 10 ~ (-9) [2.1g ~ (16.3) 脳 10 ~ (-9)) and 11.6 脳 10 ~ (-9) ~ (9)) respectively. Conclusion when children without rhinitis use tidal breathing method, they are 4.6 脳 10 ~ (-9)) [1.99 ~ (9) 脳 10 ~ (-9)) and 10 脳 10 ~ (-9) ~ 9) [6.525.8) 脳 10 ~ (-9)). Oral tidal breathing is a more accurate response to airway inflammation than mask tidal breathing.
【作者單位】： 廣州醫(yī)科大學(xué)附屬廣州市婦女兒童醫(yī)療中心;
【基金】：國家衛(wèi)計委衛(wèi)生行業(yè)科研專項(201502025)
【分類號】：R725.6

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