【摘要】：目的了解山東省生豬屠宰感染沙門氏菌耐藥狀況,指導(dǎo)臨床用藥。方法利用沙門氏菌血清型快速分型試劑盒鑒定血清型,微量肉湯稀釋法對(duì)298株沙門氏菌進(jìn)行8大類13種藥物的藥敏試驗(yàn)。結(jié)果鑒定出9種血清型,以德爾卑、鼠傷寒沙門氏菌為主;298株沙門氏菌對(duì)13種藥物的耐藥狀況不同,對(duì)四環(huán)素類藥物多西環(huán)素、四環(huán)素的耐藥率較高,分別為97.99%(292/298)、80.20%(239/298),對(duì)粘桿菌素E最為敏感,耐藥率僅為2.01%(6/298),其次為奧格門丁和氧氟沙星,耐藥率分別為2.35%(7/298)和4.03%(12/298),多重耐藥率為81.88%(244/298),優(yōu)勢(shì)耐藥譜型為四環(huán)素-多西環(huán)素。結(jié)論山東省生豬屠宰環(huán)節(jié)沙門菌優(yōu)勢(shì)血清型為德爾卑沙門氏菌,對(duì)不同藥物的耐藥情況不同,不同屠宰環(huán)節(jié)的耐藥性存在顯著差異,多重耐藥現(xiàn)象嚴(yán)重,耐藥譜型種類繁多。
[Abstract]:Objective to investigate the drug resistance of salmonella infection in live pigs in Shandong Province and to guide clinical drug use. Methods Salmonella serotype rapid typing kit was used to identify the serotype and 298 strains of Salmonella were tested by broth dilution method. Results 9 serotypes were identified. The resistance of 298 strains of Salmonella typhimurium to 13 drugs was different, and the resistance rate of tetracycline to doxycycline and tetracycline was higher. They were 97.99% (292 / 298) and 80.20% (239 / 298), respectively, which were the most sensitive to mucin E, and the resistance rate was only 2.01% (6 / 298), followed by Ogmentine and ofloxacin, the resistance rates were 2.35% (7 / 298) and 4.03% (12 / 298), the multidrug resistance rate was 81.88% (244 / 298), and the dominant drug resistance type was tetracyclin-doxycycline (244 / 298). Conclusion the predominant serotype of salmonella in live pigs in Shandong Province is Salmonella delpeifolia. The drug resistance to different drugs is different, and there are significant differences in drug resistance in different slaughtering links. The phenomenon of multiple drug resistance is serious, and there are many kinds of drug resistance spectrum.
【作者單位】： 中國動(dòng)物衛(wèi)生與流行病學(xué)中心動(dòng)物產(chǎn)品安全監(jiān)測(cè)室;青島農(nóng)業(yè)大學(xué);黃島出入境檢驗(yàn)檢疫局;
【基金】：國家農(nóng)產(chǎn)品質(zhì)量安全風(fēng)險(xiǎn)評(píng)估專項(xiàng)(No.GJFP2016 00703)~~
【分類號(hào)】：S852.61
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本文編號(hào)：2239905