【摘要】：試驗(yàn)選取6峰12歲健康雙峰母駝,試驗(yàn)組與對照組各3峰。周期14d,分為一期(感染前,1~3d)、二期(發(fā)病期間,4~12d)、三期(蠅蛆落地后,12~14d),每天采集血液獲得血清保存,于第4天對試驗(yàn)組進(jìn)行人工感染蠅蛆。結(jié)果顯示:對照組一期與試驗(yàn)組一期3種細(xì)胞因子含量均無顯著性差異(P0.05);對照組二期與試驗(yàn)組二期IL-10、IFN-γ含量差異顯著(P0.05),試驗(yàn)組含量較高,IL-4含量差異不顯著(P0.05);在三期中,試驗(yàn)組IL-4含量較低,IFN-γ含量較高且與對照組比較均差異顯著(P0.05)。對照組一、二、三期之間3種細(xì)胞因子含量差異均不顯著(P0.05);試驗(yàn)組IL-4含量一、二、三期間無顯著性差異(P0.05),IL-10二期含量高于一期且差異顯著(P0.05),IFN-γ二、三期含量均高于一期且差異顯著(P0.05)。結(jié)果表明:陰道蠅蛆病對雙峰駝外周血清中IL-4含量基本沒影響,但會使IL-10、IFN-γ含量升高,在蠅蛆落地后IL-10含量會降低,IFN-γ仍維持在較高水平。
[Abstract]:Six peaks and 12 years old healthy bimodal female camels were selected in the experiment. The test group and the control group each had 3 peaks. The period of 14 days was divided into one stage (1 / 3 days before infection), two stages (412 days after onset) and three (1214 days after the maggots fell to the ground). The blood samples were collected every day to obtain serum preservation, and the experimental group was artificially infected with fly maggots on the 4th day. The results showed that there was no significant difference in the contents of three cytokines between the control group and the experimental group (P0.05), while the content of IL-10,IFN- 緯 in the control group was significantly different from that in the experimental group (P0.05), but the content of IL-4 in the experimental group was higher than that in the control group (P0.05). The content of IL-4 in the experimental group was lower and the content of IFN- 緯 was higher than that in the control group (P0.05). There was no significant difference in the contents of three cytokines between the first, second and third phases of the control group (P0.05), but there was no significant difference in the content of IL-4 in the first, second and third periods (P0.05). The content of IL-10 in the second phase was higher than that in the first stage and the difference was significant (P0.05). The content of IFN- 緯 in the third phase was higher than that in the first stage and the difference was significant (P0.05). The results showed that vaginal myiasis had no effect on the IL-4 content in serum of Bactrian camel, but it would increase the content of IL-10,IFN- 緯, and the content of IL-10 would decrease after the maggots hit the ground.
【作者單位】： 內(nèi)蒙古農(nóng)業(yè)大學(xué)獸醫(yī)學(xué)院/農(nóng)業(yè)部動物疾病臨床診療技術(shù)重點(diǎn)實(shí)驗(yàn)室;內(nèi)蒙古阿拉善左旗農(nóng)牧業(yè)局獸醫(yī)局;阿拉善經(jīng)濟(jì)開發(fā)區(qū)農(nóng)牧業(yè)服務(wù)中心;內(nèi)蒙古阿拉善盟農(nóng)牧業(yè)綜合行政執(zhí)法支隊(duì);內(nèi)蒙古呼倫貝爾額爾古納市獸醫(yī)局;
【基金】：國家自然科學(xué)基金資助項(xiàng)目(31360591) 內(nèi)蒙古自治區(qū)自然科學(xué)基金資助項(xiàng)目(2012MS0421) 留學(xué)回國人員科研啟動基金資助項(xiàng)目(教外司留[2011]1139號)
【分類號】：S858.24

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