【摘要】：為了解雞內(nèi)源性抗菌肽NK-lysin的基本信息,試驗選擇雞NK-lysin的氨基酸序列通過軟件對NK-lysin的生物信息學進行了分析。結果表明:NK-lysin的等電點為5.87,分子質(zhì)量為15 231.3 u,為穩(wěn)定蛋白和親水蛋白,定位于細胞質(zhì)內(nèi),有1個跨膜區(qū)和1個信號肽,沒有糖基化位點,但有2個磷酸化位點,二級結構由α螺旋、延伸鏈、β折疊和無規(guī)則卷曲組成,存在多個抗原表位。說明雞抗菌肽NK-lysin可作用于細胞膜或某些生物分子,使菌體死亡。
[Abstract]:In order to understand the basic information of chicken endogenous antimicrobial peptide (NK-lysin), the amino acid sequence of chicken NK-lysin was selected to analyze the bioinformatics of NK-lysin by software. The results showed that the isoelectric point and molecular weight of 1: NK-lysin were 5.87 and 15 231.3 u. they were stable proteins and hydrophilic proteins, located in the cytoplasm, with a transmembrane region and a signal peptide, no glycosylation sites, but two phosphorylation sites. The secondary structure consists of 偽 helix, extension chain, 尾 -fold and irregular crimp, and there are many antigenic epitopes. The results showed that chicken antimicrobial peptide NK-lysin could act on the cell membrane or some biomolecules and kill the bacteria.
【作者單位】： 河南科技學院動物科技學院;河南省新鄉(xiāng)市畜產(chǎn)品質(zhì)量監(jiān)測檢驗中心;
【分類號】：S852.4

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