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芪楂口服液藥渣發(fā)酵前后對(duì)斷奶仔豬血漿生化參數(shù)和抗氧化能力的影響

發(fā)布時(shí)間:2018-06-23 10:30

  本文選題:芪楂口服液藥渣 + 發(fā)酵。 參考:《動(dòng)物營(yíng)養(yǎng)學(xué)報(bào)》2017年06期


【摘要】:為了探討中藥渣用于斷奶仔豬養(yǎng)殖的可行性,比較研究了芪楂口服液藥渣發(fā)酵前和發(fā)酵后對(duì)斷奶仔豬血漿生化參數(shù)和抗氧化能力的影響。試驗(yàn)選用21日齡斷奶仔豬120頭,隨機(jī)分為4組,分別為空白對(duì)照組(不添加抗生素和氧化鋅)、芪楂口服液藥渣組(添加5 kg/t芪楂口服液藥渣)、發(fā)酵芪楂口服液藥渣組(添加5 kg/t發(fā)酵芪楂口服液藥渣)和陽(yáng)性對(duì)照組(添加0.04 kg/t維吉尼亞霉素+0.2 kg/t硫酸黏桿菌素+3 000 mg/kg氧化鋅),每組5個(gè)重復(fù),每個(gè)重復(fù)6頭仔豬。試驗(yàn)期28 d。分別于試驗(yàn)第7和28天采血并測(cè)定血漿生化參數(shù)和抗氧化指標(biāo)。結(jié)果表明:試驗(yàn)第7天,發(fā)酵芪楂口服液藥渣組血漿總蛋白(TP)和球蛋白(GLB)含量顯著高于2個(gè)對(duì)照組(P0.05),白蛋白/球蛋白(ALB/GLB)值顯著低于2個(gè)對(duì)照組(P0.05),天冬氨酸氨基轉(zhuǎn)移酶活性顯著低于空白對(duì)照組(P0.05),堿性磷酸酶活性顯著低于芪楂口服液藥渣組和陽(yáng)性對(duì)照組(P0.05),甘油三酯含量顯著高于陽(yáng)性對(duì)照組(P0.05);試驗(yàn)第28天,芪楂口服液藥渣組血漿TP、總膽固醇含量顯著高于陽(yáng)性對(duì)照組(P0.05),ALB/GLB值顯著低于陽(yáng)性對(duì)照組(P0.05),發(fā)酵芪楂口服液藥渣組血漿高密度脂蛋白膽固醇含量和超氧化物歧化酶(SOD)活性顯著低于芪楂口服液藥渣組(P0.05),谷胱甘肽過氧化物酶(GSH-Px)活性顯著低于芪楂口服液藥渣組和空白對(duì)照組(P0.05)。與試驗(yàn)第7天相比,試驗(yàn)第28天芪楂口服液藥渣組血漿過氧化氫酶活性、發(fā)酵芪楂口服液藥渣組血漿TP和GLB含量以及GSH-Px活性顯著降低(P0.05),2個(gè)對(duì)照組血漿TP、GLB和ALB含量均顯著降低(P0.05),芪楂口服液藥渣組血漿SOD活性、發(fā)酵芪楂口服液藥渣組和陽(yáng)性對(duì)照組的ALB/GLB值均顯著升高(P0.05)。綜上所述,飼糧添加芪楂口服液藥渣可以提高仔豬免疫力,芪楂口服液藥渣發(fā)酵前后均對(duì)肝臟無不利影響,可作為飼料添加劑用于養(yǎng)豬生產(chǎn)。
[Abstract]:In order to explore the feasibility of Chinese medicine residue used in weaning piglets, the effects of Chinese medicine residue on plasma biochemical parameters and antioxidant capacity of weaned piglets before and after fermentation were compared. 120 weaned piglets of 21 days old were randomly divided into 4 groups. The two groups were blank control group (no antibiotics and zinc oxide), astragalus oral liquid residue group (adding 5 kg/t Qihaw oral liquid residue), fermenting QiHawthorn oral liquid drug residue group (adding 5 kg/t fermented Qihaw oral liquid medicine residue) and positive reaction. Irradiation group (0. 04 kg/t Virginia mycomycin 0.2 kg/t mucin sulfate 3 000 mg/kg zinc oxide), 5 repeats in each group, There were 6 piglets per repeat. The trial period was 28 days. Blood samples were collected on the 7th and 28th days of the experiment and plasma biochemical parameters and antioxidant indexes were measured. The results showed that on the 7th day of the experiment, The contents of plasma total protein (TP) and globulin (GLB), albumin / globulin (ALB / GLB), aspartate aminotransferase (AST) activity and aspartate aminotransferase activity were significantly higher in the fermented Qizaw oral liquid group than in the two control groups (P0.05), respectively (P0.05), and the ALB / GLB values were significantly lower than those in the control group (P0.05). In the irradiation group (P0.05), the activity of alkaline phosphatase was significantly lower than that of the residue group and the positive control group (P0.05), and the content of triglyceride was significantly higher than that of the positive control group (P0.05). The levels of plasma TPand total cholesterol in Qichaw oral liquid group were significantly higher than those in the positive control group (P0.05). The levels of plasma high density lipoprotein cholesterol and superoxide dismutase (SOD) were significantly lower in the fermented Qihaw oral liquid group than in the positive control group (P0.05). The activity of Glutathione peroxidase (GSH-Px) was significantly lower than that of Qi-Hawthorn oral liquid (P0.05) and the activity of glutathione peroxidase (GSH-Px) was significantly lower than that of Qi-Hawthorn oral liquid and blank control group (P0.05). Compared with the 7th day of the experiment, the plasma catalase activity of Qi-Hawthorn oral liquid group on the 28th day was compared with that of the control group. The contents of plasma TP, GLB and GSH-Px activity were significantly decreased (P0.05), the plasma TPH-GLB and ALB contents of two control groups were significantly decreased (P0.05), and the plasma SOD activity of Qi-Hawthorn oral liquid group was significantly lower than that of the control group (P0.05). The ALB / GLB values of the fermented Qizaegaw oral liquid group and the positive control group were significantly increased (P0.05). To sum up, the addition of Qi-Hawthorn oral liquid residue into diet could improve the immunity of piglets, and it had no adverse effect on liver before and after fermentation, and could be used as feed additive in pig production.
【作者單位】: 河南科技大學(xué)動(dòng)物科技學(xué)院;中國(guó)科學(xué)院亞熱帶農(nóng)業(yè)生態(tài)研究所湖南省畜禽健康養(yǎng)殖工程技術(shù)研究中心農(nóng)業(yè)部中南動(dòng)物營(yíng)養(yǎng)與飼料科學(xué)觀測(cè)實(shí)驗(yàn)站;湖南省植物功能成分利用協(xié)同創(chuàng)新中心;瀏陽(yáng)市畜牧獸醫(yī)水產(chǎn)局;
【基金】:湖南省戰(zhàn)略性新興產(chǎn)業(yè)科技攻關(guān)項(xiàng)目(2014GK1007) 中央駐湘科研機(jī)構(gòu)技術(shù)創(chuàng)新發(fā)展專項(xiàng)(2013TF3006) 中國(guó)工程院咨詢研究項(xiàng)目(2015-XY-41)
【分類號(hào)】:S828.5

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