本文選題：犬 + 急性腎衰竭�。� 參考：《內(nèi)蒙古農(nóng)業(yè)大學(xué)》2015年碩士論文

【摘要】：本實驗的目的是通過動物實驗與臨床病例,探討超聲評價犬急性腎衰竭的意義。本實驗使用8只實驗犬,肌肉注射50%甘油(10ml/kg),建立急性腎衰竭動物模型。在造模前、造模后6h、造模后24h對左側(cè)腎臟進行B型超聲、多普勒超聲、超聲造影檢查。在超聲檢查前,抽血化驗血清肌酐與血清尿素氮。在造模后6h與造模后24h進行病理學(xué)檢查。造模前后腎臟長度與寬度變化不明顯。造模后6h葉間動脈阻力指數(shù)升高不明顯,造模后24h阻力指數(shù)與造模前相比明顯升高。造模后6h與造模后24h,達峰時間與曲線下面積與造模前相比明顯升高。造模前后造影劑到達時間無明顯變化。造模后6h血清肌酐含量與造模前相比明顯升高,血清尿素氮與造模前相比無明顯變化。造模后24h血清肌酐與尿素氮含量與造模前相比均明顯升高。造模后6h腎臟病理改變不明顯,造模后24h可見明顯腎小管壞死病理改變。對8只臨床上患有急性腎衰竭的犬進行B型超聲及多普勒超聲檢查,并與8只健康犬做對比。病例組犬腎臟長度與寬度明顯大于對照組。急性腎衰竭患犬腎臟阻力指數(shù)明顯大于對照組。結(jié)果證明：超聲造影與多普勒超聲是早期診斷犬急性腎衰竭的敏感方法。
[Abstract]:The purpose of this experiment is to explore the significance of ultrasonic evaluation of acute renal failure in dogs through animal experiments and clinical cases. In this experiment, 8 experimental dogs were used and 50% glycerol (10ml/kg) was injected into the muscles to establish an animal model of acute renal failure. Before making the model, the model was 6h, and after the model was built, the left kidney was treated with B ultrasound, Doppler ultrasound, and ultrasound contrast examination. The serum creatinine and serum urea nitrogen were tested before the ultrasound examination. After the model 6h and the model 24h, the renal length and width were not significantly changed. The resistance index of the 6h interleaf artery was not significantly increased after the model, and the resistance index of the 24h was significantly higher than that before the model. After the model, the 6h and the model after making the model were 24h, up to 24h, up to the model after modeling. The peak time and the area under the curve were significantly higher than that before the model. The serum creatinine content in the 6h serum was significantly higher than before the model, and the serum urea nitrogen was not significantly changed before the model. The content of serum creatinine and urea nitrogen in the 24h serum was significantly higher than that before the model. The renal pathological changes were not obvious in the posterior 6h, and the pathological changes of renal tubular necrosis were observed in 24h after the model. 8 dogs with acute renal failure were examined by B ultrasound and Doppler ultrasound, and compared with 8 healthy dogs. The kidney length and width of the dog in the case group were significantly greater than those in the control group. The renal resistance index of acute renal failure was obvious. Compared with the control group, the results showed that contrast echocardiography and Doppler ultrasound were sensitive methods for early diagnosis of acute renal failure in dogs.

【學(xué)位授予單位】：內(nèi)蒙古農(nóng)業(yè)大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2015
【分類號】：S858.292

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本文編號：1872752